Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/comD1   Type   Regulator
Locus tag   SGGB_RS10195 Genome accession   NC_017576
Coordinates   2050561..2051868 (-) Length   435 a.a.
NCBI ID   WP_012962514.1    Uniprot ID   -
Organism   Streptococcus gallolyticus subsp. gallolyticus ATCC 43143     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 2045561..2056868
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SGGB_RS10150 (SGGB_1990) - 2045944..2046144 (-) 201 WP_009854991.1 hypothetical protein -
  SGGB_RS10155 (SGGB_1991) comD/comD3 2046276..2047640 (-) 1365 WP_012962511.1 sensor histidine kinase Regulator
  SGGB_RS10160 (SGGB_1992) comE/comE2 2047653..2048381 (-) 729 WP_012962512.1 LytR/AlgR family response regulator transcription factor Regulator
  SGGB_RS10165 (SGGB_1993) - 2048480..2048773 (-) 294 WP_009854994.1 bacteriocin immunity protein -
  SGGB_RS10170 (SGGB_1994) - 2048824..2049051 (-) 228 WP_009854995.1 hypothetical protein -
  SGGB_RS10175 (SGGB_1995) - 2049321..2049632 (-) 312 WP_003066564.1 bacteriocin immunity protein -
  SGGB_RS10180 (SGGB_1996) - 2049644..2049793 (-) 150 WP_009854997.1 hypothetical protein -
  SGGB_RS10185 (SGGB_1997) - 2049803..2050102 (-) 300 WP_009854998.1 DUF3884 family protein -
  SGGB_RS10190 (SGGB_1998) - 2050402..2050539 (+) 138 WP_009854999.1 hypothetical protein -
  SGGB_RS10195 (SGGB_1999) comD/comD1 2050561..2051868 (-) 1308 WP_012962514.1 sensor histidine kinase Regulator
  SGGB_RS10200 (SGGB_2000) comE/comE1 2051876..2052607 (-) 732 WP_009855001.1 response regulator transcription factor Regulator
  SGGB_RS10205 (SGGB_2001) - 2052624..2052908 (-) 285 WP_231101259.1 LytTR family DNA-binding domain-containing protein -
  SGGB_RS10210 (SGGB_2002) - 2053151..2053351 (-) 201 WP_009855003.1 hypothetical protein -
  SGGB_RS10220 (SGGB_2003) - 2053672..2054685 (-) 1014 WP_009855005.1 bacteriocin biosynthesis protein -
  SGGB_RS10225 (SGGB_2005) - 2055743..2055940 (-) 198 WP_009855009.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  SGGB_RS10230 (SGGB_2006) - 2055959..2056210 (-) 252 WP_009855010.1 bacteriocin class II family protein -
  SGGB_RS10235 (SGGB_2007) - 2056457..2056714 (+) 258 WP_009855011.1 hypothetical protein -

Sequence

Protein


Download         Length: 435 a.a.        Molecular weight: 51129.95 Da        Isoelectric Point: 7.0511

>NTDB_id=39585 SGGB_RS10195 WP_012962514.1 2050561..2051868(-) (comD/comD1) [Streptococcus gallolyticus subsp. gallolyticus ATCC 43143]
MSNYLSELAYYPVIMLIYSNVRGAKLKLWEIVTIAVTFFVIDFTWFYTIIGRILILMLLSYLRDKTLPFSLYVFYGSIPW
VIESAFKRIISFFIIPFFNFSYTDLDKNNLLFVIVEFSIILMYFMMVKLFKINFQTFIALSEIKNLRKKLIFTDVTMMFY
YVMIEFLTGMEVYGGVPNLVYRQWLVILYFIFFVLMLFYMNRSYQNWLEKEVSLAREQELHSLSVYSKQIEGLYEELRAF
RHDYANILASLKEGIDQDDMSMVRNIYNAVLEDSGKFIQHSRFNIGRLTNIDNDAIKSLLSAKFLEAESHHIEVELEVKD
KIGAPDIPLLDYVRLVSILCDNAIEAAIEAEKPAMIIACFYQGDDYLLIIDNTTKEERVPVELIYQKNYSSKGFGRGVGL
KTVNQMLKKYPNMSVQTSSKNYHFRQTIRIKKSFD

Nucleotide


Download         Length: 1308 bp        

>NTDB_id=39585 SGGB_RS10195 WP_012962514.1 2050561..2051868(-) (comD/comD1) [Streptococcus gallolyticus subsp. gallolyticus ATCC 43143]
ATGAGCAATTATCTAAGTGAACTAGCTTACTATCCTGTGATTATGTTGATTTACTCTAATGTTAGAGGAGCAAAGCTGAA
ATTGTGGGAAATAGTAACGATAGCTGTTACTTTCTTTGTCATTGATTTCACATGGTTTTACACTATTATCGGTCGTATTT
TAATTTTGATGCTTCTATCTTATTTGAGAGATAAAACCTTGCCTTTTTCTCTATACGTATTTTATGGGAGTATTCCATGG
GTTATAGAGAGTGCTTTTAAAAGAATTATTAGCTTCTTCATTATTCCATTTTTTAATTTTAGTTATACCGATTTAGATAA
AAATAATTTATTATTTGTCATTGTAGAATTTTCAATAATTCTGATGTATTTTATGATGGTGAAGTTGTTTAAAATTAACT
TTCAAACTTTTATTGCACTAAGTGAGATAAAAAATCTACGAAAGAAACTAATATTTACAGATGTAACAATGATGTTTTAC
TATGTCATGATTGAATTTCTAACAGGTATGGAAGTTTATGGTGGTGTCCCAAACTTGGTTTATCGCCAATGGTTAGTTAT
TCTTTATTTTATCTTTTTTGTTTTGATGTTATTTTATATGAATCGCTCTTATCAAAATTGGCTTGAGAAAGAAGTATCAT
TAGCGCGAGAACAAGAACTGCATTCTTTGTCGGTATATAGCAAGCAAATCGAAGGCTTATATGAAGAACTAAGAGCTTTT
CGTCATGATTATGCTAATATCTTAGCGAGTTTAAAAGAGGGAATTGACCAAGATGATATGAGCATGGTGAGAAATATTTA
TAATGCCGTTTTAGAGGATTCTGGAAAGTTTATTCAGCATAGTCGCTTCAATATTGGACGATTGACTAATATTGATAATG
ATGCGATAAAAAGCCTTTTATCAGCTAAATTTTTAGAAGCGGAATCTCATCATATTGAGGTAGAATTAGAAGTTAAAGAT
AAAATTGGAGCTCCAGATATTCCTTTGTTAGATTATGTGCGGCTCGTCTCCATTTTATGTGACAATGCGATTGAAGCGGC
TATTGAAGCTGAAAAGCCTGCCATGATTATTGCTTGTTTCTATCAAGGGGATGACTATTTACTAATTATCGATAACACCA
CAAAAGAAGAGCGAGTTCCTGTGGAATTGATTTATCAGAAGAATTATTCAAGTAAGGGCTTTGGACGAGGTGTTGGTCTT
AAAACGGTTAACCAGATGTTGAAAAAATATCCAAATATGTCGGTACAAACATCAAGTAAAAATTATCATTTCAGACAAAC
AATACGAATCAAAAAATCATTCGACTGA

Domains

Predicted by InterProScan.

GHKL domain (HATPase_c_5)

(330-430)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/comD1 Streptococcus equinus JB1

78.017

53.333

0.416

Multiple sequence alignment