Detailed information NTG0038008

Bioinformatically predicted

Overview

• Name: comB4
• Type: Machinery gene
• Locus tag: HPIN_RS03725
• Genome accession: NC_017372
• Coordinates: 793196..795778 (-)
• Length: 860 a.a.
• NCBI ID: WP_000462622.1
• Uniprot ID: -
• Organism: Helicobacter pylori India7
• Function: transformation-associated type IV transport system (predicted from homology) DNA binding and uptake

Genomic Context

Location: 788196..800778

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HPIN_RS03705 (HPIN_03855)	comB10	789112..790314 (-)	1203	WP_000814201.1	DNA type IV secretion system protein ComB10	Machinery gene
HPIN_RS03710 (HPIN_03860)	-	790311..791906 (-)	1596	WP_000621684.1	TrbG/VirB9 family P-type conjugative transfer protein	-
HPIN_RS03715 (HPIN_03865)	-	791903..793072 (-)	1170	WP_000067671.1	type IV secretion system protein	-
HPIN_RS03720 (HPIN_03870)	-	793065..793199 (-)	135	WP_000738747.1	hypothetical protein	-
HPIN_RS03725 (HPIN_03875)	comB4	793196..795778 (-)	2583	WP_000462622.1	VirB4 family type IV secretion/conjugal transfer ATPase	Machinery gene
HPIN_RS03730 (HPIN_03880)	-	795778..796014 (-)	237	WP_001183709.1	hypothetical protein	-
HPIN_RS03735 (HPIN_03885)	comB3	796025..796288 (-)	264	WP_001177712.1	hypothetical protein	Machinery gene
HPIN_RS03740 (HPIN_03890)	comB2	796299..796583 (-)	285	WP_000736106.1	TrbC/VirB2 family protein	Machinery gene
HPIN_RS03745 (HPIN_03895)	-	796580..797059 (-)	480	WP_000571127.1	hypothetical protein	-
HPIN_RS03750 (HPIN_03900)	-	797163..797951 (-)	789	WP_001140590.1	hypothetical protein	-
HPIN_RS03755 (HPIN_03905)	-	797938..798834 (-)	897	Protein_738	DEAD/DEAH box helicase family protein	-
HPIN_RS03760 (HPIN_03910)	-	798989..799549 (-)	561	WP_000388041.1	2-oxoacid:acceptor oxidoreductase family protein	-
HPIN_RS03765 (HPIN_03915)	-	799549..800370 (-)	822	WP_000885320.1	2-oxoglutarate ferredoxin oxidoreductase subunit beta	-

Sequence

Protein

• Length: 860 a.a.
• Molecular weight: 98990.04 Da
• Isoelectric Point: 8.4299

>NTDB_id=38008 HPIN_RS03725 WP_000462622.1 793196..795778(-) (comB4) [Helicobacter pylori India7]
MFENALKYCKEKAIDLLTGFVPKTYSMTEECNILGLYDDTFIITKQENLVAIMSLQGLSYSNLMQKDLEGYFDTRQNVLN
TISKDIQLRIVAKRRKEFINQSPNIDNPYANAIITQFESKEIYKTEYFLVFESITSNVKSFFEKKKLEMTTSINEELEES
SKENKQENENISNETHSNTSSNKDKKNKFKKKTTFSATSKRALLIQTIERVKNALREFKPTLLNSKEVLNFYAEYINGKY
IAFNPKLKRLSDSYIASNIHFKKDYFIIEFQNQSTFCACVGIKNYESEEISSLPISTLLHTQIELDLIFHIRSLGQFESL
NFLKTKKKLTLSKIVKNDIDDYIELVQANRLSMQECALNLVLRAKSKAKLDKSLKEILSLLNNAGLGSVTETIGLKPSYF
SFFPNNANINPRMRNQTSQVIASLILFEKNNTGFRANSWGDMPLSVFKNLDHSPYLFNFHNQEVKHKGVLAHNVARVVGH
TMIIGATGAGKTTLISYLMMSALKYPNIDILALDRLNGLYSFTKYFDGIYNEGESFHINPFSLEDSASNRAFLLHFYAQM
AKVDSYDKHNDKIEDRTALLNAIDTMYRNYNDEVKQAKFSNQELPLPFDLKEFVNSIVKTNTNILDSSFEYYLKSSLFSS
RMDSLDFKTRISTINTDSILHNDDDAGLLAYYVFHKMIDRALKINRGFLCFIDEFKSYAQNEMMNKKINEIITQARKANG
VIVLALQDINQLSEVKNAQSFIKNMGQLILYPQRNIDTKDLNDKFGIRLSDTEKHFLENTAVNEYKVLLKNMNDGSSNII
DVSLSSLGNYLQIFSSNSSMVEHIENLIKHYPTTWKEVFINNTYQKFDDKKHLEKVLCPT

Nucleotide

• Length: 2583 bp

>NTDB_id=38008 HPIN_RS03725 WP_000462622.1 793196..795778(-) (comB4) [Helicobacter pylori India7]
ATGTTTGAAAACGCTCTTAAATATTGTAAAGAAAAAGCCATAGACCTTTTAACAGGTTTTGTTCCAAAAACCTATTCTAT
GACAGAAGAATGCAATATTTTAGGCTTGTATGATGATACTTTCATCATCACTAAACAAGAAAATTTAGTCGCTATTATGT
CTTTACAAGGACTAAGTTATTCAAACTTAATGCAAAAAGATTTGGAGGGCTATTTTGATACAAGGCAAAATGTTTTAAAC
ACCATTAGTAAAGACATTCAATTAAGGATTGTCGCTAAAAGGCGTAAAGAATTTATCAACCAAAGCCCAAATATTGATAA
CCCATACGCAAACGCTATTATCACGCAATTTGAGAGCAAGGAAATCTACAAAACAGAGTATTTTTTAGTGTTTGAGAGCA
TTACTTCTAATGTCAAATCTTTCTTTGAGAAAAAGAAATTAGAAATGACTACTTCAATCAATGAAGAATTAGAAGAAAGC
TCTAAAGAGAATAAACAAGAGAATGAAAATATCTCCAATGAGACCCATTCAAATACAAGCTCTAACAAAGACAAGAAAAA
CAAGTTCAAAAAAAAGACAACCTTTAGTGCCACAAGTAAAAGAGCCTTACTCATTCAAACCATAGAAAGAGTGAAAAACG
CATTAAGGGAGTTTAAACCCACTCTTTTAAATTCTAAAGAAGTGTTGAATTTTTATGCAGAATATATCAATGGCAAATAC
ATCGCCTTTAATCCTAAACTAAAGCGACTAAGCGATAGCTATATCGCTAGTAATATCCATTTTAAAAAAGATTATTTCAT
CATTGAATTTCAAAATCAAAGCACTTTTTGTGCGTGTGTGGGGATTAAAAACTATGAGAGTGAAGAAATTTCTTCACTCC
CCATTTCCACCCTTTTACACACTCAAATTGAATTAGATTTAATCTTTCATATCCGCTCTTTAGGGCAATTTGAAAGCTTG
AATTTTTTAAAAACCAAGAAAAAGCTCACGCTTTCTAAAATCGTTAAAAATGATATTGATGATTATATAGAATTGGTGCA
AGCCAATCGTTTGAGTATGCAAGAGTGTGCCTTAAACTTAGTTTTAAGAGCTAAAAGTAAAGCAAAACTAGATAAGTCTT
TAAAAGAGATTTTATCTTTACTCAATAACGCTGGACTAGGCAGTGTTACAGAAACCATAGGGCTAAAACCATCCTATTTT
TCTTTTTTTCCTAATAACGCCAATATCAATCCTAGAATGAGAAATCAAACTTCCCAAGTGATTGCCTCTTTGATCTTGTT
TGAGAAAAATAATACAGGTTTTAGAGCAAATTCATGGGGGGATATGCCATTATCTGTGTTTAAGAACCTAGACCATAGCC
CTTATTTGTTTAACTTCCACAACCAAGAAGTCAAACATAAAGGCGTGTTAGCCCATAATGTGGCACGAGTGGTAGGACAT
ACCATGATTATTGGCGCAACAGGAGCTGGTAAAACCACGCTCATTAGCTATTTGATGATGAGTGCTTTAAAATACCCTAA
CATTGACATTCTAGCTCTTGATAGATTAAATGGCTTGTATTCTTTTACCAAGTATTTTGATGGGATTTATAATGAAGGCG
AAAGCTTTCATATTAATCCTTTTTCATTAGAAGATAGCGCAAGTAACAGAGCCTTTTTATTGCATTTTTATGCCCAAATG
GCAAAAGTAGATAGCTATGACAAACATAATGATAAGATAGAAGATAGAACAGCCCTTTTAAACGCTATTGATACCATGTA
TAGAAATTATAATGATGAAGTCAAACAAGCCAAATTTAGCAACCAAGAATTACCACTCCCTTTTGATTTAAAAGAGTTTG
TCAATTCCATTGTTAAAACCAATACAAACATTTTAGATAGCAGTTTTGAATACTATTTAAAATCTTCCTTATTTTCTAGC
CGAATGGATAGCCTAGATTTTAAAACTCGTATTAGCACCATAAATACTGATAGCATTTTACACAATGATGATGACGCTGG
GCTTTTAGCTTATTATGTGTTTCATAAGATGATTGATAGAGCTTTGAAGATCAATCGTGGGTTTTTATGTTTTATTGATG
AGTTTAAATCTTACGCTCAAAATGAAATGATGAATAAAAAAATCAATGAAATCATCACGCAAGCTAGAAAGGCTAATGGG
GTCATTGTTCTAGCCTTACAAGACATTAACCAACTTAGTGAAGTGAAAAACGCTCAAAGCTTTATTAAAAATATGGGGCA
ATTAATTTTGTATCCCCAAAGAAATATTGATACCAAAGATTTAAACGATAAATTTGGCATTAGACTAAGCGATACAGAAA
AACATTTTTTAGAAAACACCGCCGTTAATGAATACAAAGTCTTACTCAAAAACATGAATGATGGCTCATCTAACATTATA
GATGTGAGCCTTAGCTCTTTGGGTAATTACTTACAAATCTTTAGCTCCAATTCTAGCATGGTAGAACATATTGAAAATCT
TATTAAGCATTACCCTACTACTTGGAAAGAAGTCTTTATCAATAACACCTATCAAAAATTTGATGACAAAAAACACTTAG
AAAAGGTGCTTTGCCCAACATGA

Domains

Predicted by InterProScan.

• FtsK/SpoIIIE family (FtsK_SpoIIIE) (437-504)

• CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB) (214-412)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comB4	Helicobacter pylori 26695	47.325	97.791	0.463