Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilT   Type   Machinery gene
Locus tag   MCR_RS01565 Genome accession   NC_014147
Coordinates   351699..352748 (-) Length   349 a.a.
NCBI ID   WP_003658879.1    Uniprot ID   Q5URQ6
Organism   Moraxella catarrhalis BBH18     
Function   type IV pilus retraction (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 346699..357748
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MCR_RS01545 (MCR_0330) - 348666..349553 (-) 888 WP_003662705.1 LysR family transcriptional regulator -
  MCR_RS01550 (MCR_0331) - 349811..350443 (+) 633 WP_036335617.1 DedA family protein -
  MCR_RS01555 (MCR_0332) - 350507..350875 (-) 369 WP_003657805.1 outer membrane protein assembly factor BamE -
  MCR_RS01560 (MCR_0333) fur 351109..351549 (+) 441 WP_003657811.1 ferric iron uptake transcriptional regulator -
  MCR_RS01565 (MCR_0335) pilT 351699..352748 (-) 1050 WP_003658879.1 type IV pilus twitching motility protein PilT Machinery gene
  MCR_RS01570 (MCR_0336) - 353066..353776 (+) 711 WP_003658880.1 YggS family pyridoxal phosphate-dependent enzyme -
  MCR_RS01575 (MCR_0337) - 353830..355521 (-) 1692 WP_003669375.1 NAD+ synthase -
  MCR_RS01580 (MCR_0338) - 355770..356045 (+) 276 WP_003658884.1 hypothetical protein -
  MCR_RS01585 (MCR_0339) - 356107..356454 (-) 348 WP_003657819.1 cell division protein ZapA -
  MCR_RS01590 (MCR_0340) - 356490..356849 (-) 360 WP_003657821.1 hypothetical protein -

Sequence

Protein


Download         Length: 349 a.a.        Molecular weight: 38773.67 Da        Isoelectric Point: 6.8269

>NTDB_id=37186 MCR_RS01565 WP_003658879.1 351699..352748(-) (pilT) [Moraxella catarrhalis BBH18]
MNTPDLMGLLRFAHQKNASDLHLSAQQPIMLRIDGNLLPMDITPIDTDGIMQMLRLVMDDTDYHQWQHNLEHDFVLSLDG
IARFRVNVFFQAHGAAAVFRVIKTHIPSLQQLSYDEYVYDSMLKIAKLQAGLVLITGATGSGKSTTLASFIDHINQHQKK
HIITIEDPIEYEHSSKLSLINQRQVGKDTRSFQNALRSALREDPDVILVGELRDLETIRLALTAAETGHLVLATLHTVNA
PKSIDRIIEVFDAGEKHMIRTMLADSLKAVVAQRLLPAQGGGRVAAFEILTHTPAVAHLIRENKISQLPSVIQTSLAQGM
IDLTQSLSRLAETGKITPATANEQINMLR

Nucleotide


Download         Length: 1050 bp        

>NTDB_id=37186 MCR_RS01565 WP_003658879.1 351699..352748(-) (pilT) [Moraxella catarrhalis BBH18]
ATGAATACGCCTGATTTGATGGGGTTATTAAGATTTGCCCATCAAAAAAACGCTTCAGATTTACATTTATCCGCCCAACA
GCCCATTATGCTGCGTATTGATGGCAATCTTTTGCCCATGGACATCACGCCCATTGATACAGATGGTATCATGCAGATGC
TACGCCTTGTGATGGATGACACAGATTATCATCAATGGCAACACAATCTTGAACATGATTTTGTACTTTCGCTTGATGGC
ATCGCTCGCTTTCGGGTGAATGTATTTTTTCAGGCACACGGTGCGGCGGCTGTTTTTCGGGTGATAAAAACACACATTCC
CAGCCTACAACAGTTAAGCTATGATGAATATGTTTATGATAGTATGCTAAAAATAGCCAAGCTTCAGGCAGGCTTAGTAC
TCATCACAGGAGCAACAGGCTCAGGCAAATCAACGACACTTGCCAGTTTCATCGACCACATCAACCAACACCAAAAAAAG
CACATTATCACCATTGAAGATCCCATTGAATATGAGCATAGCTCCAAGCTTTCGCTGATTAATCAAAGGCAAGTCGGTAA
AGATACCCGAAGCTTTCAAAATGCCCTACGCTCAGCGTTGCGTGAAGATCCTGATGTGATCTTAGTTGGCGAACTTCGTG
ATCTTGAGACCATTCGCTTGGCACTGACAGCTGCCGAAACTGGGCATTTGGTGCTGGCAACCTTGCACACGGTCAACGCC
CCAAAGAGCATTGACCGTATCATTGAGGTGTTTGATGCTGGCGAAAAACACATGATTCGCACGATGCTCGCCGACTCACT
AAAGGCAGTGGTCGCCCAAAGGCTATTGCCTGCCCAAGGCGGTGGTCGTGTGGCAGCGTTTGAGATTCTCACGCATACGC
CTGCGGTTGCCCATTTGATTCGTGAAAATAAAATTTCTCAGCTACCTTCTGTCATTCAGACCAGTTTGGCCCAAGGTATG
ATTGATTTGACGCAATCTTTATCACGCTTGGCTGAAACAGGCAAAATTACGCCAGCCACTGCCAACGAACAAATCAATAT
GCTGCGATAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(13-277)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q5URQ6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilT Vibrio cholerae O1 biovar El Tor strain E7946

52.478

98.281

0.516
  pilT Vibrio cholerae strain A1552

52.478

98.281

0.516
  pilT Acinetobacter baylyi ADP1

53.116

96.562

0.513
  pilT Neisseria meningitidis 8013

53.593

95.702

0.513
  pilT Legionella pneumophila strain Lp02

52.802

97.135

0.513
  pilT Legionella pneumophila strain ERS1305867

52.802

97.135

0.513
  pilT Neisseria gonorrhoeae MS11

53.293

95.702

0.51
  pilT Acinetobacter baumannii strain A118

51.632

96.562

0.499
  pilT Acinetobacter baumannii D1279779

51.632

96.562

0.499
  pilT Acinetobacter nosocomialis M2

51.632

96.562

0.499
  pilT Pseudomonas stutzeri DSM 10701

50.588

97.421

0.493
  pilT Pseudomonas aeruginosa PAK

49.706

97.421

0.484
  pilT Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539

48.318

93.696

0.453
  pilU Pseudomonas stutzeri DSM 10701

41.818

94.556

0.395
  pilU Acinetobacter baylyi ADP1

40.118

97.135

0.39
  pilU Vibrio cholerae strain A1552

39.877

93.41

0.372

Multiple sequence alignment