Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC/cglC   Type   Machinery gene
Locus tag   EQH37_RS09755 Genome accession   NZ_CP035243
Coordinates   1929487..1929813 (-) Length   108 a.a.
NCBI ID   WP_000738629.1    Uniprot ID   A0AAW9W4H4
Organism   Streptococcus pneumoniae strain TVO_1901946     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1924487..1934813
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH37_RS09715 (EQH37_10255) rnpA 1924514..1924885 (-) 372 WP_000739244.1 ribonuclease P protein component -
  EQH37_RS10880 - 1924902..1925033 (-) 132 WP_000768904.1 hypothetical protein -
  EQH37_RS09720 (EQH37_10260) - 1925034..1926224 (-) 1191 WP_000167756.1 acetate kinase -
  EQH37_RS09725 (EQH37_10265) comYH 1926275..1927228 (-) 954 WP_061367493.1 class I SAM-dependent methyltransferase Machinery gene
  EQH37_RS09730 - 1927289..1927876 (-) 588 Protein_1917 class I SAM-dependent methyltransferase -
  EQH37_RS09735 (EQH37_10280) comGG/cglG 1928013..1928423 (-) 411 WP_000265621.1 competence type IV pilus minor pilin ComGG Machinery gene
  EQH37_RS09740 (EQH37_10285) comGF/cglF 1928401..1928862 (-) 462 WP_000250540.1 competence type IV pilus minor pilin ComGF Machinery gene
  EQH37_RS09745 (EQH37_10290) comGE/cglE 1928825..1929127 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  EQH37_RS09750 (EQH37_10295) comGD/cglD 1929090..1929494 (-) 405 WP_000588013.1 competence type IV pilus minor pilin ComGD Machinery gene
  EQH37_RS09755 (EQH37_10300) comGC/cglC 1929487..1929813 (-) 327 WP_000738629.1 comG operon protein ComGC Machinery gene
  EQH37_RS09760 (EQH37_10305) comGB/cglB 1929815..1930831 (-) 1017 WP_074017570.1 competence type IV pilus assembly protein ComGB Machinery gene
  EQH37_RS09765 (EQH37_10310) comGA/cglA/cilD 1930779..1931720 (-) 942 WP_000249548.1 competence type IV pilus ATPase ComGA Machinery gene
  EQH37_RS09770 (EQH37_10315) - 1931796..1932161 (-) 366 WP_000286415.1 DUF1033 family protein -
  EQH37_RS09775 (EQH37_10320) - 1932312..1933370 (-) 1059 WP_050145166.1 zinc-dependent alcohol dehydrogenase family protein -
  EQH37_RS09780 (EQH37_10325) nagA 1933533..1934684 (-) 1152 WP_061367521.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence

Protein


Download         Length: 108 a.a.        Molecular weight: 12228.43 Da        Isoelectric Point: 10.1877

>NTDB_id=337241 EQH37_RS09755 WP_000738629.1 1929487..1929813(-) (comGC/cglC) [Streptococcus pneumoniae strain TVO_1901946]
MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLEKNEDASLRKLQV
DGRITEEQAKAYKEYHDKNGGANRKVND

Nucleotide


Download         Length: 327 bp        

>NTDB_id=337241 EQH37_RS09755 WP_000738629.1 1929487..1929813(-) (comGC/cglC) [Streptococcus pneumoniae strain TVO_1901946]
ATGAAAAAAATGATGACATTCTTGAAAAAAGCTAAGGTTAAAGCTTTTACATTGGTGGAAATGTTGGTGGTCTTGCTGAT
TATCAGCGTGCTTTTCTTGCTCTTTGTACCTAATCTGACCAAGCAAAAAGAAGCAGTCAATGACAAAGGAAAAGCAGCTG
TTGTTAAGGTGGTGGAAAGCCAGGCAGAACTTTATAGCTTAGAAAAGAATGAAGATGCTAGCCTAAGAAAGTTACAAGTA
GATGGACGCATCACGGAAGAACAGGCTAAAGCTTATAAAGAATACCATGATAAAAATGGAGGAGCAAATCGTAAAGTCAA
TGATTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(11-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus pneumoniae Rx1

99.074

100

0.991
  comGC/cglC Streptococcus pneumoniae D39

99.074

100

0.991
  comGC/cglC Streptococcus pneumoniae R6

99.074

100

0.991
  comGC/cglC Streptococcus pneumoniae TIGR4

98.148

100

0.981
  comGC/cglC Streptococcus mitis SK321

93.519

100

0.935
  comGC/cglC Streptococcus mitis NCTC 12261

91.176

94.444

0.861
  comYC Streptococcus gordonii str. Challis substr. CH1

66.99

95.37

0.639
  comYC Streptococcus mutans UA140

61.765

94.444

0.583
  comYC Streptococcus mutans UA159

61.765

94.444

0.583
  comYC Streptococcus suis isolate S10

69.136

75

0.519
  comGC Lactococcus lactis subsp. cremoris KW2

53.922

94.444

0.509
  comGC Staphylococcus aureus MW2

48.837

79.63

0.389
  comGC Staphylococcus aureus N315

48.837

79.63

0.389
  comGC Latilactobacillus sakei subsp. sakei 23K

45.349

79.63

0.361

Multiple sequence alignment