Detailed information NTG0337238

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: EQH37_RS09740
• Genome accession: NZ_CP035243
• Coordinates: 1928401..1928862 (-)
• Length: 153 a.a.
• NCBI ID: WP_000250540.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain TVO_1901946
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1923401..1933862

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH37_RS09710 (EQH37_10250)	-	1923715..1924539 (-)	825	WP_201454401.1	membrane protein insertase YidC	-
EQH37_RS09715 (EQH37_10255)	rnpA	1924514..1924885 (-)	372	WP_000739244.1	ribonuclease P protein component	-
EQH37_RS10880	-	1924902..1925033 (-)	132	WP_000768904.1	hypothetical protein	-
EQH37_RS09720 (EQH37_10260)	-	1925034..1926224 (-)	1191	WP_000167756.1	acetate kinase	-
EQH37_RS09725 (EQH37_10265)	comYH	1926275..1927228 (-)	954	WP_061367493.1	class I SAM-dependent methyltransferase	Machinery gene
EQH37_RS09730	-	1927289..1927876 (-)	588	Protein_1917	class I SAM-dependent methyltransferase	-
EQH37_RS09735 (EQH37_10280)	comGG/cglG	1928013..1928423 (-)	411	WP_000265621.1	competence type IV pilus minor pilin ComGG	Machinery gene
EQH37_RS09740 (EQH37_10285)	comGF/cglF	1928401..1928862 (-)	462	WP_000250540.1	competence type IV pilus minor pilin ComGF	Machinery gene
EQH37_RS09745 (EQH37_10290)	comGE/cglE	1928825..1929127 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
EQH37_RS09750 (EQH37_10295)	comGD/cglD	1929090..1929494 (-)	405	WP_000588013.1	competence type IV pilus minor pilin ComGD	Machinery gene
EQH37_RS09755 (EQH37_10300)	comGC/cglC	1929487..1929813 (-)	327	WP_000738629.1	comG operon protein ComGC	Machinery gene
EQH37_RS09760 (EQH37_10305)	comGB/cglB	1929815..1930831 (-)	1017	WP_074017570.1	competence type IV pilus assembly protein ComGB	Machinery gene
EQH37_RS09765 (EQH37_10310)	comGA/cglA/cilD	1930779..1931720 (-)	942	WP_000249548.1	competence type IV pilus ATPase ComGA	Machinery gene
EQH37_RS09770 (EQH37_10315)	-	1931796..1932161 (-)	366	WP_000286415.1	DUF1033 family protein	-
EQH37_RS09775 (EQH37_10320)	-	1932312..1933370 (-)	1059	WP_050145166.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17850.40 Da
• Isoelectric Point: 8.0016

>NTDB_id=337238 EQH37_RS09740 WP_000250540.1 1928401..1928862(-) (comGF/cglF) [Streptococcus pneumoniae strain TVO_1901946]
MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQTMSQLLISEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGN
RLYMKQDGKDIAIGKSKSDDFRKTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEKS

Nucleotide

• Length: 462 bp

>NTDB_id=337238 EQH37_RS09740 WP_000250540.1 1928401..1928862(-) (comGF/cglF) [Streptococcus pneumoniae strain TVO_1901946]
ATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAAGGTCAAGGCTTTTACCTTGTTAGAATCCCTACTTGCCCTCAT
TGTCATCAGTGGGGGATTACTCCTTTTTCAAACTATGAGTCAGCTCCTCATTTCAGAAGTTCGCTACCAGCAACAAAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGGACCAACTTGAGGCAGAATTAGACCGTTCGCAGTTCGAAAAAGTAGAAGGCAAT
CGCCTATACATGAAGCAAGATGGCAAGGACATCGCCATCGGTAAGTCAAAGTCAGACGATTTTCGTAAAACCGATGCTAG
TGGACGGGGGTATCAGCCTATGGTTTATGGCCTCAAATCAGCTCAGATTACAGAGGACAATCAACTGGTTCATTTTCGTT
TCCAGTTTCAAAAAGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGAAAAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (45-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	94.771	100	0.948
comGF/cglF	Streptococcus pneumoniae D39	94.771	100	0.948
comGF/cglF	Streptococcus pneumoniae R6	94.771	100	0.948
comGF/cglF	Streptococcus pneumoniae TIGR4	94.771	100	0.948
comGF/cglF	Streptococcus mitis SK321	93.464	100	0.935
comGF/cglF	Streptococcus mitis NCTC 12261	92.157	100	0.922