Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   EQH37_RS09745 Genome accession   NZ_CP035243
Coordinates   1928825..1929127 (-) Length   100 a.a.
NCBI ID   WP_000413382.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901946     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1923825..1934127
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH37_RS09715 (EQH37_10255) rnpA 1924514..1924885 (-) 372 WP_000739244.1 ribonuclease P protein component -
  EQH37_RS10880 - 1924902..1925033 (-) 132 WP_000768904.1 hypothetical protein -
  EQH37_RS09720 (EQH37_10260) - 1925034..1926224 (-) 1191 WP_000167756.1 acetate kinase -
  EQH37_RS09725 (EQH37_10265) comYH 1926275..1927228 (-) 954 WP_061367493.1 class I SAM-dependent methyltransferase Machinery gene
  EQH37_RS09730 - 1927289..1927876 (-) 588 Protein_1917 class I SAM-dependent methyltransferase -
  EQH37_RS09735 (EQH37_10280) comGG/cglG 1928013..1928423 (-) 411 WP_000265621.1 competence type IV pilus minor pilin ComGG Machinery gene
  EQH37_RS09740 (EQH37_10285) comGF/cglF 1928401..1928862 (-) 462 WP_000250540.1 competence type IV pilus minor pilin ComGF Machinery gene
  EQH37_RS09745 (EQH37_10290) comGE/cglE 1928825..1929127 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  EQH37_RS09750 (EQH37_10295) comGD/cglD 1929090..1929494 (-) 405 WP_000588013.1 competence type IV pilus minor pilin ComGD Machinery gene
  EQH37_RS09755 (EQH37_10300) comGC/cglC 1929487..1929813 (-) 327 WP_000738629.1 comG operon protein ComGC Machinery gene
  EQH37_RS09760 (EQH37_10305) comGB/cglB 1929815..1930831 (-) 1017 WP_074017570.1 competence type IV pilus assembly protein ComGB Machinery gene
  EQH37_RS09765 (EQH37_10310) comGA/cglA/cilD 1930779..1931720 (-) 942 WP_000249548.1 competence type IV pilus ATPase ComGA Machinery gene
  EQH37_RS09770 (EQH37_10315) - 1931796..1932161 (-) 366 WP_000286415.1 DUF1033 family protein -
  EQH37_RS09775 (EQH37_10320) - 1932312..1933370 (-) 1059 WP_050145166.1 zinc-dependent alcohol dehydrogenase family protein -

Sequence

Protein


Download         Length: 100 a.a.        Molecular weight: 11108.08 Da        Isoelectric Point: 9.7273

>NTDB_id=337239 EQH37_RS09745 WP_000413382.1 1928825..1929127(-) (comGE/cglE) [Streptococcus pneumoniae strain TVO_1901946]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVSINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide


Download         Length: 303 bp        

>NTDB_id=337239 EQH37_RS09745 WP_000413382.1 1928825..1929127(-) (comGE/cglE) [Streptococcus pneumoniae strain TVO_1901946]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCCTGCAGACGGGGCAAAATCAGGTAAGCATCAACGGAGTTGAGATTCAGGTATTTTCT
AGTGAAAAAGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(16-97)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus pneumoniae Rx1

100

100

1
  comGE/cglE Streptococcus pneumoniae D39

100

100

1
  comGE/cglE Streptococcus pneumoniae R6

100

100

1
  comGE/cglE Streptococcus pneumoniae TIGR4

100

100

1
  comGE/cglE Streptococcus mitis NCTC 12261

98

100

0.98
  comGE/cglE Streptococcus mitis SK321

98

100

0.98
  comYE Streptococcus mutans UA140

44.444

90

0.4
  comYE Streptococcus mutans UA159

44.444

90

0.4

Multiple sequence alignment