Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   EXT04_RS00180 Genome accession   NZ_CP035944
Coordinates   33922..34512 (+) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain AR24.2b     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 28922..39512
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EXT04_RS22875 ysdE 29893..29967 (+) 75 WP_211180519.1 protein YsdE -
  EXT04_RS00155 (EXT04_00155) tisB 30230..30319 (-) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  EXT04_RS00160 (EXT04_00160) - 30507..31204 (+) 698 WP_094096600.1 IS1-like element IS1A family transposase -
  EXT04_RS00165 (EXT04_00165) ivbL 31661..31759 (+) 99 WP_001315912.1 ilvB operon leader peptide IvbL -
  EXT04_RS00170 (EXT04_00170) ilvB 31865..33553 (+) 1689 WP_000168480.1 acetolactate synthase large subunit -
  EXT04_RS00175 (EXT04_00175) ilvN 33557..33847 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  EXT04_RS00180 (EXT04_00180) letA 33922..34512 (+) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  EXT04_RS00185 (EXT04_00185) uhpB 34512..36014 (+) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  EXT04_RS00190 (EXT04_00190) uhpC 36024..37343 (+) 1320 WP_000936566.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  EXT04_RS00195 (EXT04_00195) uhpT 37481..38872 (+) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=306556 EXT04_RS00180 WP_000633668.1 33922..34512(+) (letA) [Escherichia coli strain AR24.2b]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=306556 EXT04_RS00180 WP_000633668.1 33922..34512(+) (letA) [Escherichia coli strain AR24.2b]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAACTGCTAAGCCAGCTGCCGAAAGGTATGGCGACAATAATGCTCTCTGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTCTCCAAACGCTGTAGCCCTGACGA
ACTGATTGCGGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGCGAACGGCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCTGCC
GAACTGGGCTTGTCGCCGAAAACGGTGCACGTCCATCGCGCCAACCTGATGGAAAAACTGGGTGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378

Multiple sequence alignment