Detailed information NTG0302936

Bioinformatically predicted

Overview

• Name: ruvB
• Type: Machinery gene
• Locus tag: ETT50_RS00340
• Genome accession: NZ_CP035449
• Coordinates: 54013..55011 (+)
• Length: 332 a.a.
• NCBI ID: WP_014407198.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain emm56
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 49013..60011

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ETT50_RS00325 (ETT50_00325)	-	50021..51439 (+)	1419	WP_011888524.1	hypothetical protein	-
ETT50_RS00330 (ETT50_00330)	purB	51459..52751 (+)	1293	WP_030126529.1	adenylosuccinate lyase	-
ETT50_RS00335 (ETT50_00335)	comR	52882..53793 (+)	912	WP_032464762.1	XRE family transcriptional regulator	Regulator
ETT50_RS09480	comS	53884..53982 (+)	99	WP_020833188.1	quorum-sensing system DWW-type pheromone	Regulator
ETT50_RS00340 (ETT50_00340)	ruvB	54013..55011 (+)	999	WP_014407198.1	Holliday junction branch migration DNA helicase RuvB	Machinery gene
ETT50_RS00345 (ETT50_00345)	-	55149..55586 (+)	438	WP_014635221.1	low molecular weight protein-tyrosine-phosphatase	-
ETT50_RS00350 (ETT50_00350)	-	55609..56010 (+)	402	WP_002986671.1	MORN repeat-containing protein	-
ETT50_RS00355 (ETT50_00355)	-	56007..57782 (+)	1776	WP_032464763.1	acyltransferase family protein	-

Sequence

Protein

• Length: 332 a.a.
• Molecular weight: 37581.11 Da
• Isoelectric Point: 5.3005

>NTDB_id=302936 ETT50_RS00340 WP_014407198.1 54013..55011(+) (ruvB) [Streptococcus pyogenes strain emm56]
MARILDNNVMGNEEFSDRTLRPQYLHEYIGQDKVKEQFAIFIEAAKRRDESLDHVLLFGPPGLGKTTMAFVIANELGVNL
KQTSGPAVEKAGDLVAILNELEPGDILFIDEIHRMPMSVEEVLYSAMEDFYIDIMIGAGDTSRSIHLDLPPFTLIGATTR
AGMLSNPLRARFGITGHMEYYQEKDLTEIVERTATIFEIKIDHEAARKLACRSRGTPRIANRLLKRVRDYAQIIGDGIIT
SQITDRALTMLDVDREGLDYIDQKILRTMIEMYQGGPVGLGTLSVNIAEERNTVEEMYEPYLIQKGFLMRTRTGRVATQK
AYRHLGYPYQNT

Nucleotide

• Length: 999 bp

>NTDB_id=302936 ETT50_RS00340 WP_014407198.1 54013..55011(+) (ruvB) [Streptococcus pyogenes strain emm56]
ATGGCTAGAATTTTAGACAATAATGTAATGGGAAATGAGGAGTTTTCGGATCGGACTCTTCGCCCTCAATATCTACACGA
ATATATTGGACAAGATAAAGTTAAGGAACAATTCGCTATTTTTATAGAAGCAGCTAAAAGACGTGACGAATCTTTAGACC
ATGTTTTATTATTTGGACCTCCAGGACTGGGAAAAACAACAATGGCATTTGTGATTGCCAATGAATTGGGAGTTAATTTA
AAGCAAACTTCAGGTCCTGCCGTTGAGAAAGCTGGAGATTTGGTAGCTATTTTAAATGAATTAGAACCAGGGGATATTTT
GTTTATTGATGAAATTCACCGCATGCCAATGTCTGTCGAGGAAGTACTATATAGTGCTATGGAAGACTTCTATATTGATA
TTATGATTGGCGCTGGAGATACTAGTCGTAGTATTCATTTGGATCTGCCTCCATTTACATTGATTGGTGCTACTACACGT
GCAGGCATGTTATCTAATCCCCTCAGAGCTCGTTTTGGTATCACTGGTCACATGGAATACTATCAAGAAAAGGATTTGAC
AGAGATTGTGGAGCGTACAGCTACTATTTTTGAAATAAAAATAGACCATGAAGCTGCACGGAAATTAGCTTGTCGCAGTA
GAGGAACGCCCCGCATTGCTAATCGATTACTAAAACGAGTGCGTGACTATGCTCAAATTATTGGTGATGGCATCATAACG
TCTCAAATAACTGATAGAGCTTTGACTATGTTAGATGTTGACCGCGAAGGTCTCGATTACATTGATCAGAAAATTTTACG
AACGATGATTGAGATGTATCAGGGAGGACCAGTTGGTTTGGGGACATTATCTGTGAATATTGCCGAGGAGCGTAATACAG
TTGAAGAGATGTATGAACCCTACTTAATTCAAAAAGGCTTTCTCATGCGAACACGAACAGGTCGTGTAGCGACGCAAAAG
GCTTATCGTCATCTTGGCTATCCCTATCAAAACACTTAA

Domains

Predicted by InterProScan.

• RuvB C-terminal winged helix domain (WHD_RuvB) (256-325)

• RuvB AAA lid domain (AAA_lid_4) (181-254)

• Holliday junction DNA helicase RuvB P-loop domain (RuvB_N) (20-178)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ruvB	Streptococcus pneumoniae R6	84.848	99.398	0.843
ruvB	Streptococcus pneumoniae D39	84.848	99.398	0.843
ruvB	Streptococcus pneumoniae TIGR4	84.545	99.398	0.84
ruvB	Bacillus subtilis subsp. subtilis str. 168	58.824	97.289	0.572
ruvB	Helicobacter pylori 26695	48.936	99.096	0.485
ruvB	Synechocystis sp. PCC 6803	50.16	94.277	0.473