Detailed information    

insolico Bioinformatically predicted

Overview


Name   comGC/cglC   Type   Machinery gene
Locus tag   SK637_RS01020 Genome accession   NZ_CP028415
Coordinates   209038..209364 (+) Length   108 a.a.
NCBI ID   WP_033688035.1    Uniprot ID   -
Organism   Streptococcus mitis strain SK637     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 204038..214364
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SK637_RS00995 (SK637_00198) nagA 204172..205323 (+) 1152 WP_033688030.1 N-acetylglucosamine-6-phosphate deacetylase -
  SK637_RS01000 (SK637_00199) - 205486..206544 (+) 1059 WP_033688031.1 zinc-dependent alcohol dehydrogenase family protein -
  SK637_RS01005 (SK637_00200) - 206690..207055 (+) 366 WP_033688032.1 DUF1033 family protein -
  SK637_RS01010 (SK637_00201) comGA/cglA/cilD 207131..208072 (+) 942 WP_033688033.1 competence type IV pilus ATPase ComGA Machinery gene
  SK637_RS01015 (SK637_00202) comGB/cglB 208020..209036 (+) 1017 WP_080710441.1 competence type IV pilus assembly protein ComGB Machinery gene
  SK637_RS01020 (SK637_00203) comGC/cglC 209038..209364 (+) 327 WP_033688035.1 competence type IV pilus major pilin ComGC Machinery gene
  SK637_RS01025 (SK637_00204) comGD/cglD 209357..209761 (+) 405 WP_000588010.1 competence type IV pilus minor pilin ComGD Machinery gene
  SK637_RS01030 (SK637_00205) comGE/cglE 209724..210026 (+) 303 WP_272898261.1 competence type IV pilus minor pilin ComGE Machinery gene
  SK637_RS01035 (SK637_00206) comGF/cglF 209989..210450 (+) 462 WP_033688037.1 competence type IV pilus minor pilin ComGF Machinery gene
  SK637_RS01040 (SK637_00207) comGG/cglG 210428..210838 (+) 411 WP_033688038.1 competence type IV pilus minor pilin ComGG Machinery gene
  SK637_RS01045 (SK637_00208) - 210871..211458 (+) 588 WP_033688039.1 class I SAM-dependent methyltransferase -
  SK637_RS01050 (SK637_00209) comYH 211519..212472 (+) 954 WP_033688040.1 class I SAM-dependent methyltransferase Machinery gene
  SK637_RS01055 (SK637_00210) - 212522..213712 (+) 1191 WP_033688041.1 acetate kinase -
  SK637_RS01060 (SK637_00211) rnpA 213862..214233 (+) 372 WP_033688042.1 ribonuclease P protein component -

Sequence


Protein


Download         Length: 108 a.a.        Molecular weight: 12080.26 Da        Isoelectric Point: 10.2400

>NTDB_id=284675 SK637_RS01020 WP_033688035.1 209038..209364(+) (comGC/cglC) [Streptococcus mitis strain SK637]
MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLLLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLDKNEDASLSKLQA
DGRITKEQAKAYNEYYTKNGGANRKVND

Nucleotide


Download         Length: 327 bp        

>NTDB_id=284675 SK637_RS01020 WP_033688035.1 209038..209364(+) (comGC/cglC) [Streptococcus mitis strain SK637]
ATGAAAAAAATGATGACATTCTTGAAAAAAGCGAAAGTGAAGGCTTTCACACTTGTGGAAATGTTGGTGGTCTTGCTCAT
CATCAGCGTGCTTCTATTACTTTTTGTACCTAATCTGACCAAGCAAAAAGAAGCAGTCAACGACAAAGGAAAAGCTGCTG
TTGTTAAGGTGGTGGAAAGCCAGGCAGAACTTTATAGCTTAGATAAAAATGAAGATGCTAGCCTAAGCAAGTTACAAGCA
GATGGGCGAATCACAAAAGAACAGGCTAAAGCCTATAATGAATACTATACAAAAAATGGAGGGGCAAATCGTAAAGTCAA
TGATTAA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus mitis SK321

98.148

100

0.981

  comGC/cglC Streptococcus pneumoniae Rx1

93.519

100

0.935

  comGC/cglC Streptococcus pneumoniae D39

93.519

100

0.935

  comGC/cglC Streptococcus pneumoniae R6

93.519

100

0.935

  comGC/cglC Streptococcus pneumoniae TIGR4

93.519

100

0.935

  comGC/cglC Streptococcus mitis NCTC 12261

95.918

90.741

0.87

  comYC Streptococcus gordonii str. Challis substr. CH1

68.932

95.37

0.657

  comYC Streptococcus mutans UA140

64.706

94.444

0.611

  comYC Streptococcus mutans UA159

64.706

94.444

0.611

  comGC Lactococcus lactis subsp. cremoris KW2

55.882

94.444

0.528

  comYC Streptococcus suis isolate S10

69.136

75

0.519

  comGC Staphylococcus aureus MW2

50

79.63

0.398

  comGC Staphylococcus aureus N315

50

79.63

0.398


Multiple sequence alignment