Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   SK637_RS01030 Genome accession   NZ_CP028415
Coordinates   209724..210026 (+) Length   100 a.a.
NCBI ID   WP_272898261.1    Uniprot ID   -
Organism   Streptococcus mitis strain SK637     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 204724..215026
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SK637_RS01000 (SK637_00199) - 205486..206544 (+) 1059 WP_033688031.1 zinc-dependent alcohol dehydrogenase family protein -
  SK637_RS01005 (SK637_00200) - 206690..207055 (+) 366 WP_033688032.1 DUF1033 family protein -
  SK637_RS01010 (SK637_00201) comGA/cglA/cilD 207131..208072 (+) 942 WP_033688033.1 competence type IV pilus ATPase ComGA Machinery gene
  SK637_RS01015 (SK637_00202) comGB/cglB 208020..209036 (+) 1017 WP_080710441.1 competence type IV pilus assembly protein ComGB Machinery gene
  SK637_RS01020 (SK637_00203) comGC/cglC 209038..209364 (+) 327 WP_033688035.1 competence type IV pilus major pilin ComGC Machinery gene
  SK637_RS01025 (SK637_00204) comGD/cglD 209357..209761 (+) 405 WP_000588010.1 competence type IV pilus minor pilin ComGD Machinery gene
  SK637_RS01030 (SK637_00205) comGE/cglE 209724..210026 (+) 303 WP_272898261.1 competence type IV pilus minor pilin ComGE Machinery gene
  SK637_RS01035 (SK637_00206) comGF/cglF 209989..210450 (+) 462 WP_033688037.1 competence type IV pilus minor pilin ComGF Machinery gene
  SK637_RS01040 (SK637_00207) comGG/cglG 210428..210838 (+) 411 WP_033688038.1 competence type IV pilus minor pilin ComGG Machinery gene
  SK637_RS01045 (SK637_00208) - 210871..211458 (+) 588 WP_033688039.1 class I SAM-dependent methyltransferase -
  SK637_RS01050 (SK637_00209) comYH 211519..212472 (+) 954 WP_033688040.1 class I SAM-dependent methyltransferase Machinery gene
  SK637_RS01055 (SK637_00210) - 212522..213712 (+) 1191 WP_033688041.1 acetate kinase -
  SK637_RS01060 (SK637_00211) rnpA 213862..214233 (+) 372 WP_033688042.1 ribonuclease P protein component -

Sequence

Protein


Download         Length: 100 a.a.        Molecular weight: 11145.17 Da        Isoelectric Point: 10.0522

>NTDB_id=284677 SK637_RS01030 WP_272898261.1 209724..210026(+) (comGE/cglE) [Streptococcus mitis strain SK637]
MEKLNALRKQKIRAVILLEALVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKIALQTGQNQVKINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide


Download         Length: 303 bp        

>NTDB_id=284677 SK637_RS01030 WP_272898261.1 209724..210026(+) (comGE/cglE) [Streptococcus mitis strain SK637]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCATTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCAACCCTCCTTTTGGGACAAATTCAGAAAAATAGGCAAGAAGAAGCAAAAATATTGCAAAAGGAAGAAG
TATTGCGGGTAGCTAAGATTGCCTTGCAGACAGGTCAAAATCAGGTAAAGATAAACGGAGTGGAGATTCAGGTGTTTTCT
AGTGAAAAAGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(16-97)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus mitis SK321

97

100

0.97
  comGE/cglE Streptococcus pneumoniae Rx1

97

100

0.97
  comGE/cglE Streptococcus pneumoniae D39

97

100

0.97
  comGE/cglE Streptococcus pneumoniae R6

97

100

0.97
  comGE/cglE Streptococcus pneumoniae TIGR4

97

100

0.97
  comGE/cglE Streptococcus mitis NCTC 12261

96

100

0.96
  comYE Streptococcus mutans UA140

43.333

90

0.39
  comYE Streptococcus mutans UA159

43.333

90

0.39

Multiple sequence alignment