Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC/cglC   Type   Machinery gene
Locus tag   BWR56_RS08865 Genome accession   NZ_CP019562
Coordinates   1789090..1789413 (-) Length   107 a.a.
NCBI ID   WP_000735800.1    Uniprot ID   A0A0F2DUU0
Organism   Streptococcus oralis strain S.MIT/ORALIS-351     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1784090..1794413
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BWR56_RS08825 (BWR56_1747) rnpA 1784216..1784587 (-) 372 WP_000748120.1 ribonuclease P protein component -
  BWR56_RS08830 (BWR56_1748) - 1784737..1785927 (-) 1191 WP_049505568.1 acetate kinase -
  BWR56_RS08835 (BWR56_1749) comYH 1785978..1786931 (-) 954 WP_049505567.1 class I SAM-dependent methyltransferase Machinery gene
  BWR56_RS08840 (BWR56_1750) - 1786990..1787580 (-) 591 WP_049505566.1 class I SAM-dependent methyltransferase -
  BWR56_RS08845 (BWR56_1751) comGG/cglG 1787613..1788026 (-) 414 WP_049505565.1 competence type IV pilus minor pilin ComGG Machinery gene
  BWR56_RS08850 (BWR56_1752) comGF/cglF 1788004..1788465 (-) 462 WP_049505564.1 competence type IV pilus minor pilin ComGF Machinery gene
  BWR56_RS08855 (BWR56_1753) comGE/cglE 1788428..1788730 (-) 303 WP_192832458.1 competence type IV pilus minor pilin ComGE Machinery gene
  BWR56_RS08860 (BWR56_1754) comGD/cglD 1788693..1789127 (-) 435 WP_049505563.1 competence type IV pilus minor pilin ComGD Machinery gene
  BWR56_RS08865 (BWR56_1755) comGC/cglC 1789090..1789413 (-) 324 WP_000735800.1 competence type IV pilus major pilin ComGC Machinery gene
  BWR56_RS08870 (BWR56_1756) comGB/cglB 1789415..1790431 (-) 1017 WP_076984831.1 competence type IV pilus assembly protein ComGB Machinery gene
  BWR56_RS08875 (BWR56_1757) comGA/cglA/cilD 1790379..1791320 (-) 942 WP_049505562.1 competence type IV pilus ATPase ComGA Machinery gene
  BWR56_RS08880 (BWR56_1758) - 1791390..1791755 (-) 366 WP_000286399.1 DUF1033 family protein -
  BWR56_RS08885 (BWR56_1759) nagA 1791909..1793060 (-) 1152 WP_076984832.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence

Protein


Download         Length: 107 a.a.        Molecular weight: 11835.95 Da        Isoelectric Point: 10.0527

>NTDB_id=216351 BWR56_RS08865 WP_000735800.1 1789090..1789413(-) (comGC/cglC) [Streptococcus oralis strain S.MIT/ORALIS-351]
MKKLMTNLKKAKVKAFTLVEMLVVLLIISVLLLLFVPNLTKQKDAVDDKGKAAVVKVVESQAELYSLDKNEDASLSKLQA
DGRITAEQAKAYKDYHAKQKTSQTVAD

Nucleotide


Download         Length: 324 bp        

>NTDB_id=216351 BWR56_RS08865 WP_000735800.1 1789090..1789413(-) (comGC/cglC) [Streptococcus oralis strain S.MIT/ORALIS-351]
ATGAAAAAACTCATGACAAATTTAAAAAAAGCCAAGGTTAAAGCTTTCACTTTGGTAGAAATGTTAGTCGTCCTTTTAAT
CATCAGTGTTCTTCTCTTGCTCTTTGTGCCCAATTTGACCAAGCAAAAGGATGCCGTAGATGATAAAGGAAAAGCTGCTG
TTGTCAAGGTCGTAGAAAGCCAGGCAGAGCTCTATAGTCTGGACAAGAATGAAGATGCTAGCCTTAGCAAATTACAAGCA
GACGGTCGTATCACAGCTGAGCAAGCTAAAGCTTATAAAGACTACCATGCAAAACAAAAAACAAGTCAAACTGTTGCAGA
TTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(11-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0F2DUU0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus mitis NCTC 12261

93.458

100

0.935
  comGC/cglC Streptococcus mitis SK321

90.909

92.523

0.841
  comGC/cglC Streptococcus pneumoniae R6

88.889

92.523

0.822
  comGC/cglC Streptococcus pneumoniae Rx1

88.889

92.523

0.822
  comGC/cglC Streptococcus pneumoniae D39

88.889

92.523

0.822
  comGC/cglC Streptococcus pneumoniae TIGR4

87.879

92.523

0.813
  comYC Streptococcus gordonii str. Challis substr. CH1

67.619

98.131

0.664
  comYC Streptococcus mutans UA140

69.072

90.654

0.626
  comYC Streptococcus mutans UA159

69.072

90.654

0.626
  comYC Streptococcus suis isolate S10

67.045

82.243

0.551
  comGC Lactococcus lactis subsp. cremoris KW2

56.436

94.393

0.533

Multiple sequence alignment