Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB/cglB   Type   Machinery gene
Locus tag   BWR56_RS08870 Genome accession   NZ_CP019562
Coordinates   1789415..1790431 (-) Length   338 a.a.
NCBI ID   WP_076984831.1    Uniprot ID   -
Organism   Streptococcus oralis strain S.MIT/ORALIS-351     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1784415..1795431
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BWR56_RS08830 (BWR56_1748) - 1784737..1785927 (-) 1191 WP_049505568.1 acetate kinase -
  BWR56_RS08835 (BWR56_1749) comYH 1785978..1786931 (-) 954 WP_049505567.1 class I SAM-dependent methyltransferase Machinery gene
  BWR56_RS08840 (BWR56_1750) - 1786990..1787580 (-) 591 WP_049505566.1 class I SAM-dependent methyltransferase -
  BWR56_RS08845 (BWR56_1751) comGG/cglG 1787613..1788026 (-) 414 WP_049505565.1 competence type IV pilus minor pilin ComGG Machinery gene
  BWR56_RS08850 (BWR56_1752) comGF/cglF 1788004..1788465 (-) 462 WP_049505564.1 competence type IV pilus minor pilin ComGF Machinery gene
  BWR56_RS08855 (BWR56_1753) comGE/cglE 1788428..1788730 (-) 303 WP_192832458.1 competence type IV pilus minor pilin ComGE Machinery gene
  BWR56_RS08860 (BWR56_1754) comGD/cglD 1788693..1789127 (-) 435 WP_049505563.1 competence type IV pilus minor pilin ComGD Machinery gene
  BWR56_RS08865 (BWR56_1755) comGC/cglC 1789090..1789413 (-) 324 WP_000735800.1 competence type IV pilus major pilin ComGC Machinery gene
  BWR56_RS08870 (BWR56_1756) comGB/cglB 1789415..1790431 (-) 1017 WP_076984831.1 competence type IV pilus assembly protein ComGB Machinery gene
  BWR56_RS08875 (BWR56_1757) comGA/cglA/cilD 1790379..1791320 (-) 942 WP_049505562.1 competence type IV pilus ATPase ComGA Machinery gene
  BWR56_RS08880 (BWR56_1758) - 1791390..1791755 (-) 366 WP_000286399.1 DUF1033 family protein -
  BWR56_RS08885 (BWR56_1759) nagA 1791909..1793060 (-) 1152 WP_076984832.1 N-acetylglucosamine-6-phosphate deacetylase -
  BWR56_RS08890 (BWR56_1760) - 1793201..1795018 (-) 1818 WP_076984833.1 acyltransferase family protein -

Sequence

Protein


Download         Length: 338 a.a.        Molecular weight: 38476.58 Da        Isoelectric Point: 9.6792

>NTDB_id=216352 BWR56_RS08870 WP_076984831.1 1789415..1790431(-) (comGB/cglB) [Streptococcus oralis strain S.MIT/ORALIS-351]
MDISQVFRLKRKKLATAKQKKIITLFNNLFSSGFHLVEIISFLGRSALLEKDYVAQMHQGLSQGKSFSEMMASLGFSSAI
VTQLSLAEVHGNLHLSLGKIEEYLDNLSKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATQIIGNLPQIF
LGLVLVCSLSVLLALTFYKRSSKMRVFSMLARIPFLGIFVQTYLTAYYAREWGNMISQGMELTQIFQIMQEQGSQLFKEI
GQDMAQALQNGREFSQTIATYPFFKKELSLIIEYGEVKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIV
LLYAAMLMPMYQNMEVNF

Nucleotide


Download         Length: 1017 bp        

>NTDB_id=216352 BWR56_RS08870 WP_076984831.1 1789415..1790431(-) (comGB/cglB) [Streptococcus oralis strain S.MIT/ORALIS-351]
ATGGATATATCACAAGTCTTCAGGCTGAAACGGAAAAAATTAGCTACAGCTAAGCAGAAGAAAATCATCACCTTGTTTAA
CAATCTCTTCTCCAGCGGCTTTCATTTGGTGGAAATTATTTCTTTTTTGGGCAGAAGTGCCCTGCTGGAAAAGGACTATG
TGGCCCAGATGCACCAAGGCTTGTCTCAGGGTAAATCATTCTCAGAAATGATGGCTAGTTTAGGCTTTTCAAGTGCTATT
GTGACCCAGTTATCTCTAGCTGAAGTGCATGGAAATCTTCACCTGAGTCTGGGGAAGATAGAAGAATATCTGGATAATTT
GTCCAAGGTCAAGAAAAAGTTAATCGAAGTAGCGACCTATCCTTTGATTTTGCTGGGATTTCTCCTGCTAATCATGCTGG
GGTTGAGAAACTATCTACTTCCCCAACTGGACAGTAGCAATATCGCCACCCAAATCATTGGAAATCTGCCACAAATATTT
CTGGGACTAGTGTTGGTTTGCTCTCTATCTGTACTTTTAGCCCTCACTTTCTACAAAAGAAGTTCCAAGATGCGGGTCTT
CTCAATGTTAGCACGGATTCCCTTTCTGGGAATCTTTGTCCAGACCTATCTGACGGCCTATTATGCGCGTGAATGGGGCA
ATATGATTTCGCAGGGAATGGAGCTGACGCAGATTTTTCAGATCATGCAGGAACAAGGTTCCCAGCTCTTTAAAGAAATC
GGTCAAGATATGGCTCAAGCCCTGCAAAATGGCCGCGAATTTTCTCAAACCATAGCGACCTATCCTTTCTTTAAAAAGGA
GTTGAGTCTCATCATCGAGTATGGGGAAGTCAAGTCCAAGCTGGGGAGTGAGTTGGAAATCTATGCTGAAAAAACTTGGG
AAGCCTTTTTTACCCGAGTCAACCGCACTATGAACTTAGTGCAGCCACTGGTTTTTATCTTTGTGGCCCTGATTATCGTT
TTACTTTATGCGGCAATGCTTATGCCCATGTATCAAAATATGGAGGTAAATTTTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(24-141)

Type II secretion system (T2SS), protein F (T2SSF)

(209-329)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB/cglB Streptococcus mitis SK321

93.491

100

0.935
  comGB/cglB Streptococcus mitis NCTC 12261

93.491

100

0.935
  comGB/cglB Streptococcus pneumoniae Rx1

90.828

100

0.908
  comGB/cglB Streptococcus pneumoniae D39

90.828

100

0.908
  comGB/cglB Streptococcus pneumoniae R6

90.828

100

0.908
  comGB/cglB Streptococcus pneumoniae TIGR4

90.828

100

0.908
  comYB Streptococcus gordonii str. Challis substr. CH1

73.512

99.408

0.731
  comYB Streptococcus mutans UA140

59.561

94.379

0.562
  comYB Streptococcus mutans UA159

59.561

94.379

0.562
  comGB Lactococcus lactis subsp. cremoris KW2

51.775

100

0.518

Multiple sequence alignment