Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   BWR56_RS08855 Genome accession   NZ_CP019562
Coordinates   1788428..1788730 (-) Length   100 a.a.
NCBI ID   WP_192832458.1    Uniprot ID   -
Organism   Streptococcus oralis strain S.MIT/ORALIS-351     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1783428..1793730
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BWR56_RS08825 (BWR56_1747) rnpA 1784216..1784587 (-) 372 WP_000748120.1 ribonuclease P protein component -
  BWR56_RS08830 (BWR56_1748) - 1784737..1785927 (-) 1191 WP_049505568.1 acetate kinase -
  BWR56_RS08835 (BWR56_1749) comYH 1785978..1786931 (-) 954 WP_049505567.1 class I SAM-dependent methyltransferase Machinery gene
  BWR56_RS08840 (BWR56_1750) - 1786990..1787580 (-) 591 WP_049505566.1 class I SAM-dependent methyltransferase -
  BWR56_RS08845 (BWR56_1751) comGG/cglG 1787613..1788026 (-) 414 WP_049505565.1 competence type IV pilus minor pilin ComGG Machinery gene
  BWR56_RS08850 (BWR56_1752) comGF/cglF 1788004..1788465 (-) 462 WP_049505564.1 competence type IV pilus minor pilin ComGF Machinery gene
  BWR56_RS08855 (BWR56_1753) comGE/cglE 1788428..1788730 (-) 303 WP_192832458.1 competence type IV pilus minor pilin ComGE Machinery gene
  BWR56_RS08860 (BWR56_1754) comGD/cglD 1788693..1789127 (-) 435 WP_049505563.1 competence type IV pilus minor pilin ComGD Machinery gene
  BWR56_RS08865 (BWR56_1755) comGC/cglC 1789090..1789413 (-) 324 WP_000735800.1 competence type IV pilus major pilin ComGC Machinery gene
  BWR56_RS08870 (BWR56_1756) comGB/cglB 1789415..1790431 (-) 1017 WP_076984831.1 competence type IV pilus assembly protein ComGB Machinery gene
  BWR56_RS08875 (BWR56_1757) comGA/cglA/cilD 1790379..1791320 (-) 942 WP_049505562.1 competence type IV pilus ATPase ComGA Machinery gene
  BWR56_RS08880 (BWR56_1758) - 1791390..1791755 (-) 366 WP_000286399.1 DUF1033 family protein -
  BWR56_RS08885 (BWR56_1759) nagA 1791909..1793060 (-) 1152 WP_076984832.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence

Protein


Download         Length: 100 a.a.        Molecular weight: 11125.03 Da        Isoelectric Point: 7.0152

>NTDB_id=216349 BWR56_RS08855 WP_192832458.1 1788428..1788730(-) (comGE/cglE) [Streptococcus oralis strain S.MIT/ORALIS-351]
MEKLNALRKQKIKAVILLEAVVALAVFASIATLLLGQIQKNRQEEAEILQKEEVLRVAKMALQTGQNQVNINGVEVQVFA
SEKGLEVYHGSDKLLDLKEQ

Nucleotide


Download         Length: 303 bp        

>NTDB_id=216349 BWR56_RS08855 WP_192832458.1 1788428..1788730(-) (comGE/cglE) [Streptococcus oralis strain S.MIT/ORALIS-351]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAAGGCAGTGATCTTACTAGAAGCAGTAGTAGCTTTGGCTGTGTT
TGCCAGCATTGCGACCCTTCTTTTGGGACAAATTCAGAAAAATAGACAAGAAGAGGCAGAAATCTTGCAAAAGGAAGAAG
TCTTGCGTGTGGCGAAGATGGCCTTGCAAACAGGTCAAAATCAGGTAAACATAAACGGAGTGGAGGTTCAGGTGTTTGCT
AGTGAAAAGGGATTGGAGGTCTACCATGGTTCAGATAAGTTGCTCGACCTTAAAGAGCAGTAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(16-96)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus mitis NCTC 12261

89.899

99

0.89
  comGE/cglE Streptococcus pneumoniae Rx1

89.899

99

0.89
  comGE/cglE Streptococcus pneumoniae D39

89.899

99

0.89
  comGE/cglE Streptococcus pneumoniae R6

89.899

99

0.89
  comGE/cglE Streptococcus pneumoniae TIGR4

89.899

99

0.89
  comGE/cglE Streptococcus mitis SK321

88.889

99

0.88
  comYE Streptococcus mutans UA140

43.478

92

0.4
  comYE Streptococcus mutans UA159

43.478

92

0.4

Multiple sequence alignment