Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA/cglA/cilD   Type   Machinery gene
Locus tag   BWR56_RS08875 Genome accession   NZ_CP019562
Coordinates   1790379..1791320 (-) Length   313 a.a.
NCBI ID   WP_049505562.1    Uniprot ID   -
Organism   Streptococcus oralis strain S.MIT/ORALIS-351     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1785379..1796320
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BWR56_RS08835 (BWR56_1749) comYH 1785978..1786931 (-) 954 WP_049505567.1 class I SAM-dependent methyltransferase Machinery gene
  BWR56_RS08840 (BWR56_1750) - 1786990..1787580 (-) 591 WP_049505566.1 class I SAM-dependent methyltransferase -
  BWR56_RS08845 (BWR56_1751) comGG/cglG 1787613..1788026 (-) 414 WP_049505565.1 competence type IV pilus minor pilin ComGG Machinery gene
  BWR56_RS08850 (BWR56_1752) comGF/cglF 1788004..1788465 (-) 462 WP_049505564.1 competence type IV pilus minor pilin ComGF Machinery gene
  BWR56_RS08855 (BWR56_1753) comGE/cglE 1788428..1788730 (-) 303 WP_192832458.1 competence type IV pilus minor pilin ComGE Machinery gene
  BWR56_RS08860 (BWR56_1754) comGD/cglD 1788693..1789127 (-) 435 WP_049505563.1 competence type IV pilus minor pilin ComGD Machinery gene
  BWR56_RS08865 (BWR56_1755) comGC/cglC 1789090..1789413 (-) 324 WP_000735800.1 competence type IV pilus major pilin ComGC Machinery gene
  BWR56_RS08870 (BWR56_1756) comGB/cglB 1789415..1790431 (-) 1017 WP_076984831.1 competence type IV pilus assembly protein ComGB Machinery gene
  BWR56_RS08875 (BWR56_1757) comGA/cglA/cilD 1790379..1791320 (-) 942 WP_049505562.1 competence type IV pilus ATPase ComGA Machinery gene
  BWR56_RS08880 (BWR56_1758) - 1791390..1791755 (-) 366 WP_000286399.1 DUF1033 family protein -
  BWR56_RS08885 (BWR56_1759) nagA 1791909..1793060 (-) 1152 WP_076984832.1 N-acetylglucosamine-6-phosphate deacetylase -
  BWR56_RS08890 (BWR56_1760) - 1793201..1795018 (-) 1818 WP_076984833.1 acyltransferase family protein -
  BWR56_RS08895 (BWR56_1761) tgt 1795152..1796294 (-) 1143 WP_001285237.1 tRNA guanosine(34) transglycosylase Tgt -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35501.42 Da        Isoelectric Point: 5.4331

>NTDB_id=216353 BWR56_RS08875 WP_049505562.1 1790379..1791320(-) (comGA/cglA/cilD) [Streptococcus oralis strain S.MIT/ORALIS-351]
MVQEIAQKIIATAKEKKAQDIYFIPKEKSYELHMRVGDERCLVDSYEFDILAAVISHFKFVAGMNVGEKRRSQLGSCDYQ
HGEKVSSLRLSTVGDYRGHESLVIRLLHDEEQDLHFWFQDMNELGEQYRQRGLYLFAGPVGSGKTTLMHELAKSLFKGQQ
VMSIEDPVEIKQEDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVVRASLTGATVFSTIHAKSIRGVY
ERLLELGVTEEELAVVLQGVCYQRLIGGGGIVDFANKDYQEHQPTSWNEQIGQLLKDGYITSLQAETEKISYS

Nucleotide


Download         Length: 942 bp        

>NTDB_id=216353 BWR56_RS08875 WP_049505562.1 1790379..1791320(-) (comGA/cglA/cilD) [Streptococcus oralis strain S.MIT/ORALIS-351]
ATGGTACAAGAAATTGCACAGAAAATTATTGCTACTGCGAAAGAAAAGAAGGCTCAGGATATCTATTTTATCCCCAAGGA
AAAGTCCTACGAACTTCACATGCGGGTTGGAGACGAACGGTGTCTAGTTGACTCCTATGAGTTTGATATTTTAGCTGCAG
TGATTAGTCATTTCAAGTTTGTGGCGGGTATGAATGTAGGGGAGAAGAGACGTAGTCAGCTGGGATCTTGCGACTATCAG
CATGGGGAGAAGGTGTCTTCTCTGCGTTTGTCCACCGTAGGAGATTATCGGGGACATGAGAGTTTGGTCATTCGTTTGTT
GCACGATGAGGAACAGGACCTGCATTTCTGGTTTCAGGATATGAACGAACTGGGTGAGCAGTACAGGCAACGGGGCCTCT
ATCTCTTTGCTGGTCCGGTCGGCAGTGGCAAGACGACTCTGATGCACGAATTAGCCAAGTCTCTGTTTAAAGGACAGCAG
GTTATGTCCATTGAAGATCCTGTCGAGATCAAGCAGGAAGACATGCTCCAGTTGCAGTTGAATGAGGCGATTGGATTGAC
CTATGAAAATCTGATCAAACTGTCTCTTCGGCATCGCCCTGACCTCTTGATTATCGGTGAAATTCGGGATAGCGAGACGG
CGCGTGCAGTAGTTAGAGCCAGTTTGACAGGGGCGACAGTCTTTTCAACTATTCATGCCAAGAGTATCCGAGGTGTTTAT
GAACGCCTTCTGGAGTTGGGTGTGACGGAGGAGGAACTAGCAGTTGTCCTGCAAGGAGTCTGCTACCAGAGATTAATCGG
GGGAGGAGGAATCGTTGACTTTGCAAACAAAGACTATCAAGAACACCAGCCAACTAGCTGGAATGAGCAGATTGGTCAGC
TTCTTAAAGATGGATATATCACAAGTCTTCAGGCTGAAACGGAAAAAATTAGCTACAGCTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

89.137

100

0.891
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

88.179

100

0.882
  comGA/cglA/cilD Streptococcus pneumoniae D39

88.179

100

0.882
  comGA/cglA/cilD Streptococcus pneumoniae R6

88.179

100

0.882
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

88.179

100

0.882
  comYA Streptococcus gordonii str. Challis substr. CH1

77.742

99.042

0.77
  comYA Streptococcus mutans UA159

66.881

99.361

0.665
  comYA Streptococcus mutans UA140

66.881

99.361

0.665
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

60

99.042

0.594
  comGA Lactococcus lactis subsp. cremoris KW2

55.128

99.681

0.55
  comGA Latilactobacillus sakei subsp. sakei 23K

43.726

84.026

0.367

Multiple sequence alignment