Detailed information NTG0216348

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: BWR56_RS08850
• Genome accession: NZ_CP019562
• Coordinates: 1788004..1788465 (-)
• Length: 153 a.a.
• NCBI ID: WP_049505564.1
• Uniprot ID: -
• Organism: Streptococcus oralis strain S.MIT/ORALIS-351
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1783004..1793465

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BWR56_RS08820 (BWR56_1746)	-	1783414..1784241 (-)	828	WP_000728097.1	membrane protein insertase YidC	-
BWR56_RS08825 (BWR56_1747)	rnpA	1784216..1784587 (-)	372	WP_000748120.1	ribonuclease P protein component	-
BWR56_RS08830 (BWR56_1748)	-	1784737..1785927 (-)	1191	WP_049505568.1	acetate kinase	-
BWR56_RS08835 (BWR56_1749)	comYH	1785978..1786931 (-)	954	WP_049505567.1	class I SAM-dependent methyltransferase	Machinery gene
BWR56_RS08840 (BWR56_1750)	-	1786990..1787580 (-)	591	WP_049505566.1	class I SAM-dependent methyltransferase	-
BWR56_RS08845 (BWR56_1751)	comGG/cglG	1787613..1788026 (-)	414	WP_049505565.1	competence type IV pilus minor pilin ComGG	Machinery gene
BWR56_RS08850 (BWR56_1752)	comGF/cglF	1788004..1788465 (-)	462	WP_049505564.1	competence type IV pilus minor pilin ComGF	Machinery gene
BWR56_RS08855 (BWR56_1753)	comGE/cglE	1788428..1788730 (-)	303	WP_192832458.1	competence type IV pilus minor pilin ComGE	Machinery gene
BWR56_RS08860 (BWR56_1754)	comGD/cglD	1788693..1789127 (-)	435	WP_049505563.1	competence type IV pilus minor pilin ComGD	Machinery gene
BWR56_RS08865 (BWR56_1755)	comGC/cglC	1789090..1789413 (-)	324	WP_000735800.1	competence type IV pilus major pilin ComGC	Machinery gene
BWR56_RS08870 (BWR56_1756)	comGB/cglB	1789415..1790431 (-)	1017	WP_076984831.1	competence type IV pilus assembly protein ComGB	Machinery gene
BWR56_RS08875 (BWR56_1757)	comGA/cglA/cilD	1790379..1791320 (-)	942	WP_049505562.1	competence type IV pilus ATPase ComGA	Machinery gene
BWR56_RS08880 (BWR56_1758)	-	1791390..1791755 (-)	366	WP_000286399.1	DUF1033 family protein	-
BWR56_RS08885 (BWR56_1759)	nagA	1791909..1793060 (-)	1152	WP_076984832.1	N-acetylglucosamine-6-phosphate deacetylase	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17761.43 Da
• Isoelectric Point: 9.6237

>NTDB_id=216348 BWR56_RS08850 WP_049505564.1 1788004..1788465(-) (comGF/cglF) [Streptococcus oralis strain S.MIT/ORALIS-351]
MVQISCSTLKSSKVRAFTLLESLIALIVISGGLLLFQAMSQLLISEVRYQQQSEQKEWLLFVDQLEAELERSQFEKVEGN
RLYMKQDGKNISIGKSKSDDFRKTDTSGRGYQPMVYGLKSAQITEENQLVRFRFQFQKGLEREFIYRVEKTKS

Nucleotide

• Length: 462 bp

>NTDB_id=216348 BWR56_RS08850 WP_049505564.1 1788004..1788465(-) (comGF/cglF) [Streptococcus oralis strain S.MIT/ORALIS-351]
ATGGTTCAGATAAGTTGCTCGACCTTAAAGAGCAGTAAGGTAAGAGCGTTCACTCTATTAGAATCTCTGATTGCCCTTAT
CGTCATTAGCGGAGGCTTGCTCCTCTTTCAGGCTATGAGTCAGCTCCTCATTTCAGAAGTTCGTTACCAGCAGCAAAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGGATCAACTGGAGGCAGAGTTAGAGCGTTCGCAGTTTGAAAAGGTAGAAGGCAAT
CGCCTCTACATGAAACAAGATGGTAAGAATATCTCTATAGGGAAGTCTAAATCGGATGATTTTCGAAAAACGGATACCAG
CGGACGGGGCTACCAACCTATGGTTTATGGACTCAAATCAGCTCAAATTACAGAGGAAAATCAATTGGTTCGCTTTCGTT
TCCAATTTCAAAAGGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAACAAAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (45-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus mitis SK321	90.196	100	0.902
comGF/cglF	Streptococcus mitis NCTC 12261	89.542	100	0.895
comGF/cglF	Streptococcus pneumoniae Rx1	87.582	100	0.876
comGF/cglF	Streptococcus pneumoniae D39	87.582	100	0.876
comGF/cglF	Streptococcus pneumoniae R6	87.582	100	0.876
comGF/cglF	Streptococcus pneumoniae TIGR4	87.582	100	0.876
comGF	Lactococcus lactis subsp. cremoris KW2	41.429	91.503	0.379