Detailed information    

experimental Experimentally validated

Overview

Name   spo0J   Type   Regulator
Locus tag   SMU_RS09895 Genome accession   NC_004350
Coordinates   2032144..2032917 (+) Length   257 a.a.
NCBI ID   WP_011074697.1    Uniprot ID   Q8DRQ5
Organism   Streptococcus mutans UA159     
Function   require for competence development   
Competence regulation

Function

The htrA and spo0J genes were shown to be both individually transcribed and cotranscribed and probably have a functional connection in competence development.


Genomic Context

Location: 2027144..2037917
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMU_RS09880 (SMU.2161c) - 2028771..2029433 (-) 663 WP_002262652.1 YoaK family protein -
  SMU_RS09885 (SMU.2162c) rlmH 2029776..2030255 (-) 480 WP_002262651.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  SMU_RS09890 (SMU.2164) htrA 2030461..2031669 (+) 1209 WP_002262650.1 S1C family serine protease Regulator
  SMU_RS09895 (SMU.2165) spo0J 2032144..2032917 (+) 774 WP_011074697.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 257 a.a.        Molecular weight: 29641.37 Da        Isoelectric Point: 10.1578

>NTDB_id=382 SMU_RS09895 WP_011074697.1 2032144..2032917(+) (spo0J) [Streptococcus mutans UA159]
MMTEQLKYLNTKDINPNPYQPRLQFKTKELEELAQSIKENGLIQPIIVRKSDIFGYDLVAGERRLKAAKLAGLNKIPVII
KKISDDDSMKQAIIENLQRSDLNPIEEAKAYQNLINRNHMTHDDIAKVIGKSRPYITNSIRLLNLPLHISQALEKGLISQ
GHARLLLSIEKQDLQDKWFQKILTEQLSVHQIERALKSQTKKEKKTSKDIFLAEKEKELSQSLGLPVVIHYNKKHQGQLK
ISFSSEEDFNRLMNKLN

Nucleotide


Download         Length: 774 bp        

>NTDB_id=382 SMU_RS09895 WP_011074697.1 2032144..2032917(+) (spo0J) [Streptococcus mutans UA159]
ATGATGACTGAACAATTAAAATATCTTAATACTAAAGATATTAATCCAAATCCCTATCAACCTCGACTGCAATTTAAAAC
TAAAGAATTGGAAGAGTTAGCACAATCTATTAAAGAAAATGGCTTAATTCAACCCATTATTGTTCGAAAATCTGATATTT
TTGGCTACGATTTGGTTGCAGGAGAAAGGCGCTTAAAAGCAGCAAAATTAGCTGGATTAAATAAGATTCCTGTTATTATC
AAAAAAATTTCTGATGATGACAGTATGAAGCAAGCTATTATCGAAAATTTACAACGTTCTGATCTTAATCCTATTGAAGA
AGCCAAAGCTTACCAAAATCTCATTAATAGAAATCATATGACTCATGATGATATTGCTAAAGTAATTGGAAAATCAAGAC
CATATATTACTAACAGTATCAGATTGTTAAATCTTCCTCTGCACATCAGCCAAGCTCTTGAAAAAGGTCTAATTTCTCAA
GGACACGCACGACTTCTTTTAAGTATAGAAAAGCAAGACTTACAAGATAAATGGTTCCAAAAAATTCTTACTGAACAGTT
AAGTGTGCATCAAATTGAAAGAGCACTTAAAAGTCAAACAAAGAAAGAAAAAAAAACTTCAAAAGACATTTTTCTGGCAG
AAAAAGAAAAAGAGCTAAGTCAATCATTAGGCTTACCTGTTGTTATTCATTATAATAAAAAACATCAAGGTCAACTTAAA
ATTTCTTTTTCGTCCGAAGAAGACTTCAACAGATTAATGAACAAGTTAAACTAG

Domains

Predicted by InterproScan.

ParB/Sulfiredoxin domain (ParB_N)

(8-96)

HTH domain found in ParB protein (HTH_ParB)

(149-197)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q8DRQ5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value

References

[1] Sang-Joon Ahn et al. (2005) Role of HtrA in growth and competence of Streptococcus mutans UA159. Journal of Bacteriology 187(9):3028-38. [PMID: 15838029]