Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/sigX/comX2/sigX2   Type   Regulator
Locus tag   Spy49_1569c Genome accession   CP000829
Coordinates   1542131..1542388 (-) Length   85 a.a.
NCBI ID   ACI61829.1    Uniprot ID   -
Organism   Streptococcus pyogenes NZ131     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1537131..1547388
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Spy49_1564 - 1538267..1539112 (+) 846 ACI61824.1 Conserved hypothetical protein, possible mechanosensitive ion channel -
  Spy49_1565c - 1539177..1539737 (-) 561 ACI61825.1 hypothetical protein -
  Spy49_1566c - 1539751..1540221 (-) 471 ACI61826.1 Conserved hypothetical protein -
  Spy49_1567c thiD 1540211..1540975 (-) 765 ACI61827.1 Phosphomethylpyrimidine kinase -
  Spy49_1568c truA 1540965..1541714 (-) 750 ACI61828.1 tRNA pseudouridine synthase A -
  Spy49_1569c comX/sigX/comX2/sigX2 1542131..1542388 (-) 258 ACI61829.1 ComX2 alternate sigma factor Regulator

Sequence

Protein


Download         Length: 85 a.a.        Molecular weight: 10544.29 Da        Isoelectric Point: 9.6063

>NTDB_id=20163 Spy49_1569c ACI61829.1 1542131..1542388(-) (comX/sigX/comX2/sigX2) [Streptococcus pyogenes NZ131]
MSIETRAAFEKVKPIILKLKRHYYIQLWDRDDWLQEGHIILLQLLERYPELIEEEERLYRYFKTKFSSYLKDLLRRQEKS
KASVP

Nucleotide


Download         Length: 258 bp        

>NTDB_id=20163 Spy49_1569c ACI61829.1 1542131..1542388(-) (comX/sigX/comX2/sigX2) [Streptococcus pyogenes NZ131]
ATGTCGATAGAGACAAGAGCAGCGTTTGAAAAAGTTAAGCCCATTATTTTGAAATTAAAGCGACACTATTATATTCAATT
GTGGGATAGAGATGACTGGTTACAAGAAGGACATATTATCTTATTACAGTTACTAGAAAGGTACCCAGAGTTAATTGAGG
AAGAAGAGCGTTTATATCGCTATTTTAAAACAAAATTTTCATCTTATTTGAAAGATTTATTACGCCGTCAAGAAAAGTCA
AAAGCGTCAGTTCCATAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

97.531

95.294

0.929
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

97.531

95.294

0.929
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

97.531

95.294

0.929
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

97.531

95.294

0.929
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

96.296

95.294

0.918
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

96.296

95.294

0.918
  comX/sigX Streptococcus mutans UA159

58.108

87.059

0.506
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

57.534

85.882

0.494
  comX Streptococcus sobrinus strain NIDR 6715-7

54.667

88.235

0.482
  comX Streptococcus salivarius SK126

54.054

87.059

0.471
  comX/sigX Streptococcus salivarius strain HSISS4

54.054

87.059

0.471
  comX Streptococcus thermophilus LMG 18311

52.703

87.059

0.459
  comX Streptococcus thermophilus LMD-9

52.703

87.059

0.459
  comX/sigX Streptococcus suis D9

46.835

92.941

0.435
  comX/sigX Streptococcus suis isolate S10

46.835

92.941

0.435
  comX/sigX Streptococcus suis P1/7

46.835

92.941

0.435
  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

45.946

87.059

0.4
  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

45.946

87.059

0.4
  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

45.205

85.882

0.388
  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

43.836

85.882

0.376
  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

42.466

85.882

0.365

Multiple sequence alignment