Detailed information NTG0001447

Bioinformatically predicted

Overview

• Name: ssb
• Type: Machinery gene
• Locus tag: BW25113_RS21080
• Genome accession: NZ_CP009273
• Coordinates: 4264053..4264589 (+)
• Length: 178 a.a.
• NCBI ID: WP_000168305.1
• Uniprot ID: A0A9P2PPK2
• Organism: Escherichia coli BW25113 strain K-12
• Function: ssDNA binding (predicted from homology) DNA processing

Genomic Context

Location: 4259053..4269589

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BW25113_RS21060 (BW25113_4055)	aphA	4259342..4260055 (+)	714	WP_001226928.1	acid phosphatase AphA	-
BW25113_RS21065 (BW25113_4056)	yjbQ	4260166..4260582 (+)	417	WP_000270375.1	secondary thiamine-phosphate synthase enzyme YjbQ	-
BW25113_RS21070 (BW25113_4057)	yjbR	4260586..4260942 (+)	357	WP_000155657.1	MmcQ/YjbR family DNA-binding protein	-
BW25113_RS21075 (BW25113_4058)	uvrA	4260977..4263799 (-)	2823	WP_000357740.1	excinuclease ABC subunit UvrA	-
BW25113_RS21080 (BW25113_4059)	ssb	4264053..4264589 (+)	537	WP_000168305.1	single-stranded DNA-binding protein SSB1	Machinery gene
BW25113_RS21085 (BW25113_4060)	yjcB	4264688..4264969 (-)	282	WP_001295689.1	YjcB family protein	-
BW25113_RS21090 (BW25113_4061)	pdeC	4265399..4266985 (+)	1587	WP_000019548.1	c-di-GMP phosphodiesterase PdeC	-
BW25113_RS21095 (BW25113_4062)	soxS	4266988..4267311 (-)	324	WP_000019358.1	superoxide response transcriptional regulator SoxS	-
BW25113_RS21100 (BW25113_4063)	soxR	4267397..4267861 (+)	465	WP_000412428.1	redox-sensitive transcriptional activator SoxR	-

Regulatory network

Positive effect      

Negative effect

Regulator	Target	Regulation
sxy/tfoX	ssb	positive effect
sxy/tfoX	fimT/comN/ppdA	positive effect
sxy/tfoX	comE1/ybaV	positive effect
sxy/tfoX	pilN/comB/hofN	positive effect
sxy/tfoX	pilO/comC/hofO	positive effect
sxy/tfoX	pilB/hofB	positive effect
sxy/tfoX	pilD/pppA	positive effect
sxy/tfoX	rec2/ycaI	positive effect
sxy/tfoX	pilP/comD/hofP	positive effect
sxy/tfoX	comF/gntX	positive effect
sxy/tfoX	pilM/comA/hofM	positive effect
sxy/tfoX	pilA/ppdD	positive effect
sxy/tfoX	fimU/comO/ppdB	positive effect
sxy/tfoX	comP/ygdB	positive effect
sxy/tfoX	pilV/comQ/ppdC	positive effect
sxy/tfoX	mshC/yggT	positive effect
sxy/tfoX	pilQ/comE/hofQ	positive effect
sxy/tfoX	dprA/smf	positive effect
sxy/tfoX	pilT/yggR	positive effect
sxy/tfoX	pilC/hofC	positive effect
sxy/tfoX	pilB/ycgB	positive effect
sxy/tfoX	comM/yifB	positive effect

Sequence

Protein

• Length: 178 a.a.
• Molecular weight: 18975.00 Da
• Isoelectric Point: 5.2358

>NTDB_id=1447 BW25113_RS21080 WP_000168305.1 4264053..4264589(+) (ssb) [Escherichia coli BW25113 strain K-12]
MASRGVNKVILVGNLGQDPEVRYMPNGGAVANITLATSESWRDKATGEMKEQTEWHRVVLFGKLAEVASEYLRKGSQVYI
EGQLRTRKWTDQSGQDRYTTEVVVNVGGTMQMLGGRQGGGAPAGGNIGGGQPQGGWGQPQQPQGGNQFSGGAQSRPQQSA
PAAPSNEPPMDFDDDIPF

Nucleotide

• Length: 537 bp

>NTDB_id=1447 BW25113_RS21080 WP_000168305.1 4264053..4264589(+) (ssb) [Escherichia coli BW25113 strain K-12]
ATGGCCAGCAGAGGCGTAAACAAGGTTATTCTCGTTGGTAATCTGGGTCAGGACCCGGAAGTACGCTACATGCCAAATGG
TGGCGCAGTTGCCAACATTACGCTGGCTACTTCCGAATCCTGGCGTGATAAAGCGACCGGCGAGATGAAAGAACAGACTG
AATGGCACCGCGTTGTGCTGTTCGGCAAACTGGCAGAAGTGGCGAGCGAATATCTGCGTAAAGGTTCTCAGGTTTATATC
GAAGGTCAGCTGCGTACCCGTAAATGGACCGATCAATCCGGTCAGGATCGCTACACCACAGAAGTCGTGGTGAACGTTGG
CGGCACCATGCAGATGCTGGGTGGTCGTCAGGGTGGTGGCGCTCCGGCAGGTGGCAATATCGGTGGTGGTCAGCCGCAGG
GCGGTTGGGGTCAGCCTCAGCAGCCGCAGGGTGGCAATCAGTTCAGCGGCGGCGCGCAGTCTCGCCCGCAGCAGTCCGCT
CCGGCAGCGCCGTCTAACGAGCCGCCGATGGACTTTGATGATGACATTCCGTTCTGA

Domains

Predicted by InterproScan.

• Single-strand binding protein family (SSB) (6-112)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ssb	Vibrio cholerae strain A1552	74.444	100	0.753
ssb	Glaesserella parasuis strain SC1401	57.923	100	0.596
ssb	Neisseria meningitidis MC58	48.066	100	0.489
ssb	Neisseria gonorrhoeae MS11	48.066	100	0.489