Detailed information NTG1170464

Bioinformatically predicted

Overview

• Name: comX/sigX/comX2/sigX2
• Type: Regulator
• Locus tag: ACLV7W_RS09805
• Genome accession: NZ_OZ217346
• Coordinates: 2030380..2030859 (-)
• Length: 159 a.a.
• NCBI ID: WP_153209010.1
• Uniprot ID: A0A6I1UHB2
• Organism: Streptococcus mitis isolate S. mitis D22
• Function: activate transcription of late competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2025380..2035859

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACLV7W_RS09805 (SMID22_20180)	comX/sigX/comX2/sigX2	2030380..2030859 (-)	480	WP_153209010.1	sigma-70 family RNA polymerase sigma factor	Regulator
ACLV7W_RS09810 (SMID22_20190)	nusG	2030981..2031517 (-)	537	WP_033687381.1	transcription termination/antitermination protein NusG	-
ACLV7W_RS09815 (SMID22_20200)	secE	2031571..2031747 (-)	177	WP_001210990.1	preprotein translocase subunit SecE	-
ACLV7W_RS09820	rpmG	2031757..2031909 (-)	153	WP_001809375.1	50S ribosomal protein L33	-
ACLV7W_RS09825 (SMID22_20210)	pbp2a	2031962..2034157 (-)	2196	WP_411865868.1	penicillin-binding protein PBP2A	-
ACLV7W_RS09830 (SMID22_20220)	-	2034244..2035119 (+)	876	WP_411865869.1	RluA family pseudouridine synthase	-

Sequence

Protein

• Length: 159 a.a.
• Molecular weight: 20083.89 Da
• Isoelectric Point: 8.4254

>NTDB_id=1170464 ACLV7W_RS09805 WP_153209010.1 2030380..2030859(-) (comX/sigX/comX2/sigX2) [Streptococcus mitis isolate S. mitis D22]
MLKKLYEEVQGIVYKCRNEYYLHLWELSDWDQEGMICLHELISREEELVEDIPRLRKYFKTKFRNRILDHIRKQESQKRR
YDKEPYEEVGEISHRISEGGLWLDEYYLFHETLRDYRNKQSKEKQEELERILRHERFRGRQRVLRDLRIVFKEFDIRSR

Nucleotide

• Length: 480 bp

>NTDB_id=1170464 ACLV7W_RS09805 WP_153209010.1 2030380..2030859(-) (comX/sigX/comX2/sigX2) [Streptococcus mitis isolate S. mitis D22]
ATGCTTAAAAAATTGTATGAAGAAGTCCAAGGAATTGTATACAAGTGTAGAAATGAATATTACCTTCATTTATGGGAGTT
ATCGGATTGGGACCAAGAGGGAATGATCTGCTTACATGAATTGATCAGTAGAGAAGAAGAACTGGTAGAAGATATTCCAC
GCTTACGTAAATATTTCAAGACTAAGTTTCGTAATCGAATTTTAGACCATATCCGTAAACAAGAAAGTCAGAAGCGTAGA
TATGATAAAGAACCTTATGAAGAAGTGGGAGAGATTAGTCATCGTATCAGTGAGGGAGGTCTGTGGCTAGATGAGTATTA
TCTCTTTCATGAAACACTAAGAGATTATAGAAACAAACAAAGCAAAGAGAAGCAAGAAGAGTTAGAACGCATCTTAAGAC
ATGAACGCTTCCGAGGGCGTCAAAGAGTTCTAAGGGACTTGCGTATTGTGTTTAAAGAGTTTGATATCCGTAGTCGGTAA

Domains

No domain identified.

3D structure

• AlphaFold DB: A0A6I1UHB2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comX/sigX/comX2/sigX2	Streptococcus mitis NCTC 12261	96.203	99.371	0.956
comX/sigX/comX1/sigX1	Streptococcus mitis NCTC 12261	93.671	99.371	0.931
comX/sigX/comX2/sigX2	Streptococcus mitis SK321	91.824	100	0.918
comX/sigX/comX1/sigX1	Streptococcus mitis SK321	91.824	100	0.918
comX/comX1	Streptococcus pneumoniae D39	91.772	99.371	0.912
comX/comX2	Streptococcus pneumoniae R6	91.772	99.371	0.912
comX/comX1	Streptococcus pneumoniae R6	91.772	99.371	0.912
comX/comX2	Streptococcus pneumoniae Rx1	91.772	99.371	0.912
comX/comX1	Streptococcus pneumoniae Rx1	91.772	99.371	0.912
comX/comX2	Streptococcus pneumoniae D39	91.772	99.371	0.912
comX/comX2	Streptococcus pneumoniae TIGR4	91.139	99.371	0.906
comX/comX1	Streptococcus pneumoniae TIGR4	91.139	99.371	0.906
comR/comR2	Streptococcus gordonii str. Challis substr. CH1	50.98	96.226	0.491
comR/comR1	Streptococcus gordonii str. Challis substr. CH1	50.98	96.226	0.491
comX/sigX	Streptococcus mutans UA159	48	94.34	0.453
comX/sigX	Streptococcus suis D9	45.752	96.226	0.44
comX/sigX	Streptococcus suis isolate S10	45.752	96.226	0.44
comX/sigX	Streptococcus suis P1/7	45.752	96.226	0.44
comX/sigX/comX1/sigX1	Streptococcus pyogenes JRS4	42.953	93.711	0.403
comX/sigX/comX2/sigX2	Streptococcus pyogenes JRS4	42.953	93.711	0.403
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS8232	42.953	93.711	0.403
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS8232	42.953	93.711	0.403
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS315	42.105	95.597	0.403
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS315	42.105	95.597	0.403
comX	Streptococcus thermophilus LMG 18311	38.816	95.597	0.371
comX	Streptococcus thermophilus LMD-9	38.816	95.597	0.371
comX	Streptococcus salivarius SK126	39.333	94.34	0.371
comX/sigX	Streptococcus salivarius strain HSISS4	38.667	94.34	0.365