Detailed information    

insolico Bioinformatically predicted

Overview


Name   comX/sigX/comX2/sigX2   Type   Regulator
Locus tag   ACLV7D_RS01260 Genome accession   NZ_OZ217345
Coordinates   241310..241789 (+) Length   159 a.a.
NCBI ID   WP_218764753.1    Uniprot ID   -
Organism   Streptococcus mitis isolate S. mitis F22     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context


Location: 236310..246789
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLV7D_RS01235 (SMIF22_02400) - 237050..237925 (-) 876 WP_411865948.1 RluA family pseudouridine synthase -
  ACLV7D_RS01240 (SMIF22_02410) pbp2a 238012..240207 (+) 2196 WP_218764754.1 penicillin-binding protein PBP2A -
  ACLV7D_RS01245 rpmG 240260..240412 (+) 153 WP_001809375.1 50S ribosomal protein L33 -
  ACLV7D_RS01250 (SMIF22_02420) secE 240422..240598 (+) 177 WP_001210991.1 preprotein translocase subunit SecE -
  ACLV7D_RS01255 (SMIF22_02430) nusG 240653..241189 (+) 537 WP_000376734.1 transcription termination/antitermination protein NusG -
  ACLV7D_RS01260 (SMIF22_02440) comX/sigX/comX2/sigX2 241310..241789 (+) 480 WP_218764753.1 sigma-70 family RNA polymerase sigma factor Regulator

Sequence


Protein


Download         Length: 159 a.a.        Molecular weight: 20035.71 Da        Isoelectric Point: 6.7596

>NTDB_id=1170340 ACLV7D_RS01260 WP_218764753.1 241310..241789(+) (comX/sigX/comX2/sigX2) [Streptococcus mitis isolate S. mitis F22]
MIKELYEEVQGIVYKCRNEYYLHLWELSDWDQEGMICLHELISREEELVEDIPRLRQYFKTKFRNRILDYIRKQESHKRR
YNKEPYEEVGEISHRISEGGLWLDDYYLFHETLRDYRNKQSKEKQEELERVLRDERFRGRQRVLKDLRIVFKEFDIRTH

Nucleotide


Download         Length: 480 bp        

>NTDB_id=1170340 ACLV7D_RS01260 WP_218764753.1 241310..241789(+) (comX/sigX/comX2/sigX2) [Streptococcus mitis isolate S. mitis F22]
ATGATTAAAGAATTGTATGAAGAAGTCCAGGGAATTGTATATAAGTGTAGAAATGAATATTATCTTCATTTATGGGAGCT
ATCGGACTGGGACCAAGAGGGAATGATTTGCTTACATGAATTGATTAGTAGAGAAGAAGAATTGGTAGAAGATATCCCTC
GTTTAAGGCAATATTTCAAAACAAAATTCCGAAATCGAATTTTAGACTATATCCGTAAGCAAGAAAGCCACAAACGAAGA
TATAATAAAGAACCTTATGAAGAAGTGGGTGAGATAAGTCATCGTATAAGTGAGGGCGGTCTGTGGCTAGATGATTATTA
TCTCTTTCATGAAACACTAAGAGATTATAGAAACAAACAAAGTAAAGAGAAACAAGAAGAACTAGAACGCGTCTTAAGAG
ATGAACGCTTCCGAGGGCGTCAAAGAGTGCTAAAGGACTTACGCATTGTGTTTAAAGAGTTTGACATCCGTACTCATTAG

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

93.711

100

0.937

  comX/comX2 Streptococcus pneumoniae Rx1

93.082

100

0.931

  comX/comX1 Streptococcus pneumoniae Rx1

93.082

100

0.931

  comX/comX2 Streptococcus pneumoniae D39

93.082

100

0.931

  comX/comX1 Streptococcus pneumoniae D39

93.082

100

0.931

  comX/comX2 Streptococcus pneumoniae R6

93.082

100

0.931

  comX/comX1 Streptococcus pneumoniae R6

93.082

100

0.931

  comX/sigX/comX1/sigX1 Streptococcus mitis NCTC 12261

92.453

100

0.925

  comX/comX2 Streptococcus pneumoniae TIGR4

92.453

100

0.925

  comX/comX1 Streptococcus pneumoniae TIGR4

92.453

100

0.925

  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

91.824

100

0.918

  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

90.506

99.371

0.899

  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

49.359

98.113

0.484

  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

49.359

98.113

0.484

  comX/sigX Streptococcus mutans UA159

48

94.34

0.453

  comX/sigX Streptococcus suis isolate S10

43.046

94.969

0.409

  comX/sigX Streptococcus suis P1/7

43.046

94.969

0.409

  comX/sigX Streptococcus suis D9

43.046

94.969

0.409

  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

42.282

93.711

0.396

  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

42.282

93.711

0.396

  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

42.282

93.711

0.396

  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

42.282

93.711

0.396

  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

41.447

95.597

0.396

  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

41.447

95.597

0.396

  comX Streptococcus salivarius SK126

40

94.34

0.377

  comX/sigX Streptococcus salivarius strain HSISS4

39.333

94.34

0.371

  comX Streptococcus thermophilus LMG 18311

39.333

94.34

0.371

  comX Streptococcus thermophilus LMD-9

39.333

94.34

0.371


Multiple sequence alignment