Detailed information NTG1170093

Bioinformatically predicted

Overview

• Name: comX/comX2
• Type: Regulator
• Locus tag: ACLV65_RS01375
• Genome accession: NZ_OZ217342
• Coordinates: 256208..256687 (+)
• Length: 159 a.a.
• NCBI ID: WP_411864339.1
• Uniprot ID: -
• Organism: Streptococcus mitis isolate S. mitis B22
• Function: activate transcription of late competence genes (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	254729..255985	256208..256687	flank	223

Gene organization within MGE regions

Location: 254729..256687

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACLV65_RS01370 (SMIB22_02660)	-	254729..255985 (-)	1257	WP_411865198.1	ISL3 family transposase	-
ACLV65_RS01375 (SMIB22_02670)	comX/comX2	256208..256687 (+)	480	WP_411864339.1	sigma-70 family RNA polymerase sigma factor	Regulator

Sequence

Protein

• Length: 159 a.a.
• Molecular weight: 19950.65 Da
• Isoelectric Point: 7.0533

>NTDB_id=1170093 ACLV65_RS01375 WP_411864339.1 256208..256687(+) (comX/comX2) [Streptococcus mitis isolate S. mitis B22]
MLKELYEEVQGIVYKCRNEYYLHLWELSDWDQEGMICLHELISKEEGLVEDIPRLRKYFKTKFRNRILDYIRKQESHKRR
YDKEPYDEVGEISHRISEGGLWLDDYYLFHETLRDYRNKQSKEKQEELERVLRDERFRGRQRVLRDLRIVFKEFDIRTH

Nucleotide

• Length: 480 bp

>NTDB_id=1170093 ACLV65_RS01375 WP_411864339.1 256208..256687(+) (comX/comX2) [Streptococcus mitis isolate S. mitis B22]
ATGCTTAAAGAATTGTATGAAGAAGTCCAAGGAATTGTATACAAGTGTAGAAATGAATATTACCTTCATTTGTGGGAGTT
ATCGGACTGGGATCAAGAGGGAATGATATGTCTACATGAATTGATTAGTAAAGAAGAAGGATTAGTCGAAGATATTCCAC
GTTTAAGGAAATATTTCAAAACCAAGTTTCGAAATCGAATTTTAGACTATATCCGTAAGCAAGAAAGCCACAAACGAAGA
TATGATAAAGAACCCTATGATGAAGTGGGTGAAATCAGTCATCGTATAAGTGAGGGCGGTCTGTGGCTAGATGATTATTA
TCTCTTTCATGAAACACTAAGAGATTATAGAAACAAACAAAGTAAAGAGAAACAAGAAGAGCTAGAACGCGTCTTAAGAG
ATGAACGCTTCCGAGGGCGTCAAAGAGTGTTAAGAGACTTACGTATTGTGTTTAAAGAGTTTGACATCCGTACCCATTAG

Domains

No domain identified.

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comX/comX1	Streptococcus pneumoniae Rx1	93.711	100	0.937
comX/sigX/comX2/sigX2	Streptococcus mitis NCTC 12261	93.711	100	0.937
comX/comX2	Streptococcus pneumoniae D39	93.711	100	0.937
comX/comX1	Streptococcus pneumoniae D39	93.711	100	0.937
comX/comX2	Streptococcus pneumoniae R6	93.711	100	0.937
comX/comX1	Streptococcus pneumoniae R6	93.711	100	0.937
comX/sigX/comX1/sigX1	Streptococcus mitis NCTC 12261	93.711	100	0.937
comX/comX2	Streptococcus pneumoniae Rx1	93.711	100	0.937
comX/comX2	Streptococcus pneumoniae TIGR4	93.082	100	0.931
comX/comX1	Streptococcus pneumoniae TIGR4	93.082	100	0.931
comX/sigX/comX2/sigX2	Streptococcus mitis SK321	91.824	100	0.918
comX/sigX/comX1/sigX1	Streptococcus mitis SK321	91.772	99.371	0.912
comR/comR2	Streptococcus gordonii str. Challis substr. CH1	48.718	98.113	0.478
comR/comR1	Streptococcus gordonii str. Challis substr. CH1	48.718	98.113	0.478
comX/sigX	Streptococcus mutans UA159	45.333	94.34	0.428
comX/sigX	Streptococcus suis isolate S10	43.137	96.226	0.415
comX/sigX	Streptococcus suis D9	43.137	96.226	0.415
comX/sigX	Streptococcus suis P1/7	43.137	96.226	0.415
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS315	40.132	95.597	0.384
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS315	40.132	95.597	0.384
comX/sigX/comX1/sigX1	Streptococcus pyogenes JRS4	40.94	93.711	0.384
comX/sigX/comX2/sigX2	Streptococcus pyogenes JRS4	40.94	93.711	0.384
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS8232	40.94	93.711	0.384
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS8232	40.94	93.711	0.384
comX	Streptococcus salivarius SK126	40	94.34	0.377
comX	Streptococcus thermophilus LMG 18311	40	94.34	0.377
comX	Streptococcus thermophilus LMD-9	40	94.34	0.377
comX/sigX	Streptococcus salivarius strain HSISS4	39.333	94.34	0.371