Detailed information    

insolico Bioinformatically predicted

Overview


Name   comGC/cglC   Type   Machinery gene
Locus tag   ACLV65_RS01240 Genome accession   NZ_OZ217342
Coordinates   231972..232295 (+) Length   107 a.a.
NCBI ID   WP_172925580.1    Uniprot ID   -
Organism   Streptococcus mitis isolate S. mitis B22     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 226972..237295
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLV65_RS01215 (SMIB22_02360) nagA 227099..228250 (+) 1152 WP_001134549.1 N-acetylglucosamine-6-phosphate deacetylase -
  ACLV65_RS01220 (SMIB22_02370) - 228413..229471 (+) 1059 WP_411864324.1 zinc-dependent alcohol dehydrogenase family protein -
  ACLV65_RS01225 (SMIB22_02380) - 229622..229987 (+) 366 WP_000286405.1 DUF1033 family protein -
  ACLV65_RS01230 (SMIB22_02390) comGA/cglA/cilD 230065..231006 (+) 942 WP_411864325.1 competence type IV pilus ATPase ComGA Machinery gene
  ACLV65_RS01235 (SMIB22_02400) comGB/cglB 230954..231970 (+) 1017 WP_411865197.1 competence type IV pilus assembly protein ComGB Machinery gene
  ACLV65_RS01240 (SMIB22_02410) comGC/cglC 231972..232295 (+) 324 WP_172925580.1 competence type IV pilus major pilin ComGC Machinery gene
  ACLV65_RS01245 (SMIB22_02420) comGD/cglD 232258..232692 (+) 435 WP_411864326.1 competence type IV pilus minor pilin ComGD Machinery gene
  ACLV65_RS01250 (SMIB22_02430) comGE/cglE 232655..232957 (+) 303 WP_411864327.1 competence type IV pilus minor pilin ComGE Machinery gene
  ACLV65_RS01255 (SMIB22_02440) comGF/cglF 232920..233381 (+) 462 WP_173234886.1 competence type IV pilus minor pilin ComGF Machinery gene
  ACLV65_RS01260 (SMIB22_02450) comGG/cglG 233359..233772 (+) 414 WP_411864328.1 competence type IV pilus minor pilin ComGG Machinery gene
  ACLV65_RS01265 (SMIB22_02460) - 233805..234392 (+) 588 WP_411864329.1 class I SAM-dependent methyltransferase -
  ACLV65_RS01270 (SMIB22_02470) comYH 234453..235406 (+) 954 WP_411864330.1 class I SAM-dependent methyltransferase Machinery gene
  ACLV65_RS01275 (SMIB22_02480) - 235456..236646 (+) 1191 WP_411864331.1 acetate kinase -
  ACLV65_RS01280 (SMIB22_02490) rnpA 236796..237167 (+) 372 WP_173282963.1 ribonuclease P protein component -

Sequence


Protein


Download         Length: 107 a.a.        Molecular weight: 12044.18 Da        Isoelectric Point: 9.6932

>NTDB_id=1170086 ACLV65_RS01240 WP_172925580.1 231972..232295(+) (comGC/cglC) [Streptococcus mitis isolate S. mitis B22]
MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLLLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLDKNEEATLSKLQA
DDRITEEQAKAYKEYHAKQNTSQTVAD

Nucleotide


Download         Length: 324 bp        

>NTDB_id=1170086 ACLV65_RS01240 WP_172925580.1 231972..232295(+) (comGC/cglC) [Streptococcus mitis isolate S. mitis B22]
ATGAAAAAAATGATGACATTCTTGAAAAAAGCTAAGGTTAAAGCTTTTACACTTGTGGAGATGTTGGTGGTCTTGCTCAT
CATCAGCGTGCTTCTCTTGCTCTTTGTACCTAATCTGACCAAGCAAAAAGAGGCGGTCAATGACAAAGGAAAAGCTGCTG
TTGTTAAGGTGGTGGAAAGTCAGGCAGAGCTTTATAGTTTAGATAAAAATGAAGAGGCTACTCTAAGCAAATTACAAGCA
GATGATCGCATCACAGAAGAACAGGCTAAAGCTTATAAAGAATACCATGCTAAACAAAATACCAGTCAAACCGTTGCAGA
TTAA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus mitis NCTC 12261

97.196

100

0.972

  comGC/cglC Streptococcus mitis SK321

90.291

96.262

0.869

  comGC/cglC Streptococcus pneumoniae Rx1

88.35

96.262

0.85

  comGC/cglC Streptococcus pneumoniae D39

88.35

96.262

0.85

  comGC/cglC Streptococcus pneumoniae R6

88.35

96.262

0.85

  comGC/cglC Streptococcus pneumoniae TIGR4

87.379

96.262

0.841

  comYC Streptococcus gordonii str. Challis substr. CH1

68.571

98.131

0.673

  comYC Streptococcus mutans UA140

68.421

88.785

0.607

  comYC Streptococcus mutans UA159

68.421

88.785

0.607

  comYC Streptococcus suis isolate S10

71.605

75.701

0.542

  comGC Lactococcus lactis subsp. cremoris KW2

53.465

94.393

0.505

  comGC Staphylococcus aureus MW2

48.837

80.374

0.393

  comGC Staphylococcus aureus N315

48.837

80.374

0.393


Multiple sequence alignment