Detailed information    

insolico Bioinformatically predicted

Overview


Name   comGC/cglC   Type   Machinery gene
Locus tag   ACLV7Q_RS01065 Genome accession   NZ_OZ217341
Coordinates   202519..202842 (+) Length   107 a.a.
NCBI ID   WP_218757954.1    Uniprot ID   -
Organism   Streptococcus mitis isolate S. mitis C22     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 197519..207842
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLV7Q_RS01040 (SMIC22_01980) nagA 197648..198799 (+) 1152 WP_218757951.1 N-acetylglucosamine-6-phosphate deacetylase -
  ACLV7Q_RS01045 (SMIC22_01990) - 198962..200020 (+) 1059 WP_218757952.1 zinc-dependent alcohol dehydrogenase family protein -
  ACLV7Q_RS01050 (SMIC22_02000) - 200170..200535 (+) 366 WP_045606653.1 DUF1033 family protein -
  ACLV7Q_RS01055 (SMIC22_02010) comGA/cglA/cilD 200612..201553 (+) 942 WP_218757953.1 competence type IV pilus ATPase ComGA Machinery gene
  ACLV7Q_RS01060 (SMIC22_02020) comGB/cglB 201501..202517 (+) 1017 WP_218757970.1 competence type IV pilus assembly protein ComGB Machinery gene
  ACLV7Q_RS01065 (SMIC22_02030) comGC/cglC 202519..202842 (+) 324 WP_218757954.1 competence type IV pilus major pilin ComGC Machinery gene
  ACLV7Q_RS01070 (SMIC22_02040) comGD/cglD 202805..203239 (+) 435 WP_218757955.1 competence type IV pilus minor pilin ComGD Machinery gene
  ACLV7Q_RS01075 (SMIC22_02050) comGE/cglE 203202..203504 (+) 303 WP_000413380.1 competence type IV pilus minor pilin ComGE Machinery gene
  ACLV7Q_RS01080 (SMIC22_02060) comGF/cglF 203467..203928 (+) 462 WP_218757956.1 competence type IV pilus minor pilin ComGF Machinery gene
  ACLV7Q_RS01085 (SMIC22_02070) comGG/cglG 203906..204319 (+) 414 WP_218757957.1 competence type IV pilus minor pilin ComGG Machinery gene
  ACLV7Q_RS01090 (SMIC22_02080) - 204352..204939 (+) 588 WP_218757958.1 class I SAM-dependent methyltransferase -
  ACLV7Q_RS01095 (SMIC22_02090) comYH 205000..205953 (+) 954 WP_218757959.1 class I SAM-dependent methyltransferase Machinery gene
  ACLV7Q_RS01100 (SMIC22_02100) - 206004..207194 (+) 1191 WP_218757960.1 acetate kinase -
  ACLV7Q_RS01105 (SMIC22_02110) rnpA 207344..207715 (+) 372 WP_000739245.1 ribonuclease P protein component -

Sequence


Protein


Download         Length: 107 a.a.        Molecular weight: 12029.21 Da        Isoelectric Point: 10.0527

>NTDB_id=1170004 ACLV7Q_RS01065 WP_218757954.1 202519..202842(+) (comGC/cglC) [Streptococcus mitis isolate S. mitis C22]
MKKMMTFLKKSKVKAFTLVEMLVVLLIISVLLLLFLPNLTKQKEAVNDKGKAAVVKVVESQAELYSLDKNEDASLSKLQA
DGRITEEQAKAYKEYHAKQNKTQTVAD

Nucleotide


Download         Length: 324 bp        

>NTDB_id=1170004 ACLV7Q_RS01065 WP_218757954.1 202519..202842(+) (comGC/cglC) [Streptococcus mitis isolate S. mitis C22]
ATGAAAAAAATGATGACATTCTTGAAAAAATCTAAGGTTAAAGCTTTCACTCTGGTAGAGATGTTGGTGGTCTTGCTCAT
CATCAGCGTACTTCTCTTGCTTTTTCTACCTAATCTGACCAAACAAAAAGAAGCAGTCAACGACAAAGGAAAAGCTGCTG
TTGTTAAGGTGGTGGAAAGCCAGGCAGAGCTTTATAGCTTGGATAAAAATGAAGATGCTAGCCTAAGCAAGTTACAAGCA
GATGGGAGAATCACAGAAGAACAAGCTAAAGCTTATAAAGAATATCATGCAAAACAAAATAAGACTCAAACGGTCGCGGA
TTAA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus mitis NCTC 12261

96.262

100

0.963

  comGC/cglC Streptococcus mitis SK321

95.918

91.589

0.879

  comGC/cglC Streptococcus pneumoniae Rx1

92

93.458

0.86

  comGC/cglC Streptococcus pneumoniae D39

92

93.458

0.86

  comGC/cglC Streptococcus pneumoniae R6

92

93.458

0.86

  comGC/cglC Streptococcus pneumoniae TIGR4

91

93.458

0.85

  comYC Streptococcus gordonii str. Challis substr. CH1

69.524

98.131

0.682

  comYC Streptococcus mutans UA140

65.385

97.196

0.636

  comYC Streptococcus mutans UA159

65.385

97.196

0.636

  comYC Streptococcus suis isolate S10

69.136

75.701

0.523

  comGC Lactococcus lactis subsp. cremoris KW2

56.701

90.654

0.514

  comGC Staphylococcus aureus MW2

51.163

80.374

0.411

  comGC Staphylococcus aureus N315

51.163

80.374

0.411


Multiple sequence alignment