Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   ACLV7Q_RS01075 Genome accession   NZ_OZ217341
Coordinates   203202..203504 (+) Length   100 a.a.
NCBI ID   WP_000413380.1    Uniprot ID   -
Organism   Streptococcus mitis isolate S. mitis C22     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 198202..208504
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLV7Q_RS01045 (SMIC22_01990) - 198962..200020 (+) 1059 WP_218757952.1 zinc-dependent alcohol dehydrogenase family protein -
  ACLV7Q_RS01050 (SMIC22_02000) - 200170..200535 (+) 366 WP_045606653.1 DUF1033 family protein -
  ACLV7Q_RS01055 (SMIC22_02010) comGA/cglA/cilD 200612..201553 (+) 942 WP_218757953.1 competence type IV pilus ATPase ComGA Machinery gene
  ACLV7Q_RS01060 (SMIC22_02020) comGB/cglB 201501..202517 (+) 1017 WP_218757970.1 competence type IV pilus assembly protein ComGB Machinery gene
  ACLV7Q_RS01065 (SMIC22_02030) comGC/cglC 202519..202842 (+) 324 WP_218757954.1 competence type IV pilus major pilin ComGC Machinery gene
  ACLV7Q_RS01070 (SMIC22_02040) comGD/cglD 202805..203239 (+) 435 WP_218757955.1 competence type IV pilus minor pilin ComGD Machinery gene
  ACLV7Q_RS01075 (SMIC22_02050) comGE/cglE 203202..203504 (+) 303 WP_000413380.1 competence type IV pilus minor pilin ComGE Machinery gene
  ACLV7Q_RS01080 (SMIC22_02060) comGF/cglF 203467..203928 (+) 462 WP_218757956.1 competence type IV pilus minor pilin ComGF Machinery gene
  ACLV7Q_RS01085 (SMIC22_02070) comGG/cglG 203906..204319 (+) 414 WP_218757957.1 competence type IV pilus minor pilin ComGG Machinery gene
  ACLV7Q_RS01090 (SMIC22_02080) - 204352..204939 (+) 588 WP_218757958.1 class I SAM-dependent methyltransferase -
  ACLV7Q_RS01095 (SMIC22_02090) comYH 205000..205953 (+) 954 WP_218757959.1 class I SAM-dependent methyltransferase Machinery gene
  ACLV7Q_RS01100 (SMIC22_02100) - 206004..207194 (+) 1191 WP_218757960.1 acetate kinase -
  ACLV7Q_RS01105 (SMIC22_02110) rnpA 207344..207715 (+) 372 WP_000739245.1 ribonuclease P protein component -

Sequence

Protein


Download         Length: 100 a.a.        Molecular weight: 11135.11 Da        Isoelectric Point: 9.7273

>NTDB_id=1170006 ACLV7Q_RS01075 WP_000413380.1 203202..203504(+) (comGE/cglE) [Streptococcus mitis isolate S. mitis C22]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVNINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide


Download         Length: 303 bp        

>NTDB_id=1170006 ACLV7Q_RS01075 WP_000413380.1 203202..203504(+) (comGE/cglE) [Streptococcus mitis isolate S. mitis C22]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTAGAAGCAGTAGTCGCTTTAGCTATCTT
TGCCAGTATTGCAACCCTCCTTTTGGGACAAATTCAGAAAAATAGGCAAGAAGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCCTGCAGACAGGTCAAAATCAGGTAAACATCAACGGAGTTGAGATTCAGGTGTTTTCT
AGTGAAAAAGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCTATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(16-97)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus mitis NCTC 12261

99

100

0.99
  comGE/cglE Streptococcus pneumoniae Rx1

99

100

0.99
  comGE/cglE Streptococcus pneumoniae D39

99

100

0.99
  comGE/cglE Streptococcus pneumoniae R6

99

100

0.99
  comGE/cglE Streptococcus pneumoniae TIGR4

99

100

0.99
  comGE/cglE Streptococcus mitis SK321

98

100

0.98
  comYE Streptococcus mutans UA140

43.333

90

0.39
  comYE Streptococcus mutans UA159

43.333

90

0.39

Multiple sequence alignment