Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC/cglC   Type   Machinery gene
Locus tag   AD178_RS09950 Genome accession   NZ_OX244288
Coordinates   1924161..1924487 (-) Length   108 a.a.
NCBI ID   WP_000738634.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PT8105 isolate 2RLC4     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1919161..1929487
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AD178_RS09905 (SAMEA1463109_01999) rnpA 1919178..1919549 (-) 372 WP_000739246.1 ribonuclease P protein component -
  AD178_RS09910 - 1919566..1919697 (-) 132 WP_000768904.1 hypothetical protein -
  AD178_RS09915 (SAMEA1463109_02000) - 1919698..1920888 (-) 1191 WP_000167757.1 acetate kinase -
  AD178_RS09920 (SAMEA1463109_02001) comYH 1920939..1921892 (-) 954 WP_000345136.1 class I SAM-dependent methyltransferase Machinery gene
  AD178_RS09925 - 1921953..1922547 (-) 595 Protein_1936 methyltransferase domain-containing protein -
  AD178_RS09930 (SAMEA1463109_02004) comGG/cglG 1922684..1923097 (-) 414 WP_000265622.1 competence type IV pilus minor pilin ComGG Machinery gene
  AD178_RS09935 (SAMEA1463109_02005) comGF/cglF 1923075..1923536 (-) 462 WP_000250525.1 competence type IV pilus minor pilin ComGF Machinery gene
  AD178_RS09940 (SAMEA1463109_02006) comGE/cglE 1923499..1923801 (-) 303 WP_188109891.1 competence type IV pilus minor pilin ComGE Machinery gene
  AD178_RS09945 (SAMEA1463109_02007) comGD/cglD 1923764..1924168 (-) 405 WP_000588022.1 competence type IV pilus minor pilin ComGD Machinery gene
  AD178_RS09950 (SAMEA1463109_02008) comGC/cglC 1924161..1924487 (-) 327 WP_000738634.1 comG operon protein ComGC Machinery gene
  AD178_RS09955 (SAMEA1463109_02009) comGB/cglB 1924489..1925505 (-) 1017 WP_074017570.1 competence type IV pilus assembly protein ComGB Machinery gene
  AD178_RS09960 (SAMEA1463109_02010) comGA/cglA/cilD 1925453..1926394 (-) 942 WP_000249549.1 competence type IV pilus ATPase ComGA Machinery gene
  AD178_RS09965 (SAMEA1463109_02011) - 1926470..1926835 (-) 366 WP_000286415.1 DUF1033 family protein -
  AD178_RS09970 (SAMEA1463109_02012) - 1926986..1928044 (-) 1059 WP_000649466.1 zinc-dependent alcohol dehydrogenase family protein -
  AD178_RS09975 (SAMEA1463109_02013) nagA 1928207..1929358 (-) 1152 WP_001134461.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence

Protein


Download         Length: 108 a.a.        Molecular weight: 12189.35 Da        Isoelectric Point: 10.0305

>NTDB_id=1154359 AD178_RS09950 WP_000738634.1 1924161..1924487(-) (comGC/cglC) [Streptococcus pneumoniae strain PT8105 isolate 2RLC4]
MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLEKNEDASLSKLKE
DGRITEEQAKAYKEYHDKNGGANRKVND

Nucleotide


Download         Length: 327 bp        

>NTDB_id=1154359 AD178_RS09950 WP_000738634.1 1924161..1924487(-) (comGC/cglC) [Streptococcus pneumoniae strain PT8105 isolate 2RLC4]
ATGAAAAAAATGATGACATTCTTGAAAAAAGCTAAGGTTAAAGCTTTTACATTGGTGGAAATGTTGGTGGTCTTGCTGAT
TATCAGCGTGCTTTTCTTGCTCTTTGTACCTAATCTGACCAAGCAAAAAGAAGCAGTCAATGACAAAGGAAAAGCAGCTG
TTGTTAAGGTGGTGGAAAGCCAGGCAGAACTTTATAGCTTGGAAAAGAATGAAGATGCTAGCCTAAGCAAGTTAAAAGAA
GATGGACGCATCACGGAAGAACAGGCTAAAGCTTATAAAGAATACCATGATAAAAATGGAGGAGCAAATCGTAAAGTCAA
TGATTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(11-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus pneumoniae Rx1

97.222

100

0.972
  comGC/cglC Streptococcus pneumoniae D39

97.222

100

0.972
  comGC/cglC Streptococcus pneumoniae R6

97.222

100

0.972
  comGC/cglC Streptococcus pneumoniae TIGR4

96.296

100

0.963
  comGC/cglC Streptococcus mitis SK321

93.519

100

0.935
  comGC/cglC Streptococcus mitis NCTC 12261

91.176

94.444

0.861
  comYC Streptococcus gordonii str. Challis substr. CH1

67.961

95.37

0.648
  comYC Streptococcus mutans UA159

62.745

94.444

0.593
  comYC Streptococcus mutans UA140

62.745

94.444

0.593
  comGC Lactococcus lactis subsp. cremoris KW2

54.902

94.444

0.519
  comYC Streptococcus suis isolate S10

67.901

75

0.509
  comGC Staphylococcus aureus MW2

48.837

79.63

0.389
  comGC Staphylococcus aureus N315

48.837

79.63

0.389
  comGC Latilactobacillus sakei subsp. sakei 23K

45.349

79.63

0.361

Multiple sequence alignment