Detailed information NTG1154357

Bioinformatically predicted

Overview

• Name: comGE/cglE
• Type: Machinery gene
• Locus tag: AD178_RS09940
• Genome accession: NZ_OX244288
• Coordinates: 1923499..1923801 (-)
• Length: 100 a.a.
• NCBI ID: WP_188109891.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain PT8105 isolate 2RLC4
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1918499..1928801

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AD178_RS09905 (SAMEA1463109_01999)	rnpA	1919178..1919549 (-)	372	WP_000739246.1	ribonuclease P protein component	-
AD178_RS09910	-	1919566..1919697 (-)	132	WP_000768904.1	hypothetical protein	-
AD178_RS09915 (SAMEA1463109_02000)	-	1919698..1920888 (-)	1191	WP_000167757.1	acetate kinase	-
AD178_RS09920 (SAMEA1463109_02001)	comYH	1920939..1921892 (-)	954	WP_000345136.1	class I SAM-dependent methyltransferase	Machinery gene
AD178_RS09925	-	1921953..1922547 (-)	595	Protein_1936	methyltransferase domain-containing protein	-
AD178_RS09930 (SAMEA1463109_02004)	comGG/cglG	1922684..1923097 (-)	414	WP_000265622.1	competence type IV pilus minor pilin ComGG	Machinery gene
AD178_RS09935 (SAMEA1463109_02005)	comGF/cglF	1923075..1923536 (-)	462	WP_000250525.1	competence type IV pilus minor pilin ComGF	Machinery gene
AD178_RS09940 (SAMEA1463109_02006)	comGE/cglE	1923499..1923801 (-)	303	WP_188109891.1	competence type IV pilus minor pilin ComGE	Machinery gene
AD178_RS09945 (SAMEA1463109_02007)	comGD/cglD	1923764..1924168 (-)	405	WP_000588022.1	competence type IV pilus minor pilin ComGD	Machinery gene
AD178_RS09950 (SAMEA1463109_02008)	comGC/cglC	1924161..1924487 (-)	327	WP_000738634.1	comG operon protein ComGC	Machinery gene
AD178_RS09955 (SAMEA1463109_02009)	comGB/cglB	1924489..1925505 (-)	1017	WP_074017570.1	competence type IV pilus assembly protein ComGB	Machinery gene
AD178_RS09960 (SAMEA1463109_02010)	comGA/cglA/cilD	1925453..1926394 (-)	942	WP_000249549.1	competence type IV pilus ATPase ComGA	Machinery gene
AD178_RS09965 (SAMEA1463109_02011)	-	1926470..1926835 (-)	366	WP_000286415.1	DUF1033 family protein	-
AD178_RS09970 (SAMEA1463109_02012)	-	1926986..1928044 (-)	1059	WP_000649466.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 100 a.a.
• Molecular weight: 11081.06 Da
• Isoelectric Point: 9.7273

>NTDB_id=1154357 AD178_RS09940 WP_188109891.1 1923499..1923801(-) (comGE/cglE) [Streptococcus pneumoniae strain PT8105 isolate 2RLC4]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQSQVSINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide

• Length: 303 bp

>NTDB_id=1154357 AD178_RS09940 WP_188109891.1 1923499..1923801(-) (comGE/cglE) [Streptococcus pneumoniae strain PT8105 isolate 2RLC4]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCCTGCAGACGGGGCAAAGTCAGGTAAGCATCAACGGAGTTGAGATTCAGGTATTTTCT
AGTGAAAAAGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

• Type II secretory pathway pseudopilin (ComGE) (16-97)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGE/cglE	Streptococcus pneumoniae Rx1	99	100	0.99
comGE/cglE	Streptococcus pneumoniae D39	99	100	0.99
comGE/cglE	Streptococcus pneumoniae R6	99	100	0.99
comGE/cglE	Streptococcus pneumoniae TIGR4	99	100	0.99
comGE/cglE	Streptococcus mitis NCTC 12261	97	100	0.97
comGE/cglE	Streptococcus mitis SK321	97	100	0.97
comYE	Streptococcus mutans UA140	44.444	90	0.4
comYE	Streptococcus mutans UA159	44.444	90	0.4