Detailed information NTG1142013

Bioinformatically predicted

Overview

• Name: comGC/cglC
• Type: Machinery gene
• Locus tag: DQL12_RS10585
• Genome accession: NZ_LS483450
• Coordinates: 1942595..1942918 (-)
• Length: 107 a.a.
• NCBI ID: WP_000738628.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 4041STDY6583227
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1937595..1947918

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL12_RS10545	rnpA	1937612..1937983 (-)	372	WP_044793385.1	ribonuclease P protein component	-
DQL12_RS12510	-	1938000..1938131 (-)	132	WP_000768904.1	hypothetical protein	-
DQL12_RS10550	-	1938132..1939322 (-)	1191	WP_000167765.1	acetate kinase	-
DQL12_RS10555	comYH	1939373..1940326 (-)	954	WP_050255606.1	class I SAM-dependent methyltransferase	Machinery gene
DQL12_RS10560	-	1940387..1940981 (-)	595	Protein_1953	class I SAM-dependent methyltransferase	-
DQL12_RS10565	comGG/cglG	1941118..1941531 (-)	414	WP_050255604.1	competence type IV pilus minor pilin ComGG	Machinery gene
DQL12_RS10570	comGF/cglF	1941509..1941970 (-)	462	WP_000250520.1	competence type IV pilus minor pilin ComGF	Machinery gene
DQL12_RS10575	comGE/cglE	1941933..1942235 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
DQL12_RS10580	comGD/cglD	1942198..1942632 (-)	435	WP_033606693.1	competence type IV pilus minor pilin ComGD	Machinery gene
DQL12_RS10585	comGC/cglC	1942595..1942918 (-)	324	WP_000738628.1	comG operon protein ComGC	Machinery gene
DQL12_RS10590	comGB/cglB	1942920..1943936 (-)	1017	WP_077141332.1	competence type IV pilus assembly protein ComGB	Machinery gene
DQL12_RS10595	comGA/cglA/cilD	1943884..1944825 (-)	942	WP_000249550.1	competence type IV pilus ATPase ComGA	Machinery gene
DQL12_RS10600	-	1944901..1945266 (-)	366	WP_000286415.1	DUF1033 family protein	-
DQL12_RS10605	-	1945417..1946475 (-)	1059	WP_001861944.1	zinc-dependent alcohol dehydrogenase family protein	-
DQL12_RS10610	nagA	1946638..1947789 (-)	1152	WP_001134457.1	N-acetylglucosamine-6-phosphate deacetylase	-

Sequence

Protein

• Length: 107 a.a.
• Molecular weight: 12232.41 Da
• Isoelectric Point: 9.8887

>NTDB_id=1142013 DQL12_RS10585 WP_000738628.1 1942595..1942918(-) (comGC/cglC) [Streptococcus pneumoniae strain 4041STDY6583227]
MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLEKNEDASLRKLQD
DGRITEEQAKAYKEYHDKQNTSQIVKD

Nucleotide

• Length: 324 bp

>NTDB_id=1142013 DQL12_RS10585 WP_000738628.1 1942595..1942918(-) (comGC/cglC) [Streptococcus pneumoniae strain 4041STDY6583227]
ATGAAAAAAATGATGACATTCTTGAAAAAAGCTAAGGTTAAAGCTTTTACATTGGTGGAAATGTTGGTGGTCTTGCTGAT
TATCAGCGTGCTTTTCTTGCTCTTTGTACCTAATCTGACCAAGCAAAAAGAAGCAGTCAATGACAAAGGAAAAGCAGCTG
TTGTTAAGGTGGTGGAAAGCCAGGCAGAACTTTATAGCTTGGAAAAGAATGAAGATGCTAGCCTAAGAAAGTTACAAGAC
GATGGACGCATCACGGAAGAACAGGCTAAAGCCTATAAAGAATACCATGATAAACAAAATACTAGTCAAATCGTTAAAGA
TTAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (11-34)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGC/cglC	Streptococcus mitis NCTC 12261	93.458	100	0.935
comGC/cglC	Streptococcus pneumoniae D39	94.175	96.262	0.907
comGC/cglC	Streptococcus pneumoniae R6	94.175	96.262	0.907
comGC/cglC	Streptococcus pneumoniae Rx1	94.175	96.262	0.907
comGC/cglC	Streptococcus pneumoniae TIGR4	93.204	96.262	0.897
comGC/cglC	Streptococcus mitis SK321	88.35	96.262	0.85
comYC	Streptococcus gordonii str. Challis substr. CH1	69.388	91.589	0.636
comYC	Streptococcus mutans UA140	64.211	88.785	0.57
comYC	Streptococcus mutans UA159	64.211	88.785	0.57
comYC	Streptococcus suis isolate S10	69.136	75.701	0.523
comGC	Lactococcus lactis subsp. cremoris KW2	54.639	90.654	0.495
comGC	Staphylococcus aureus MW2	48.837	80.374	0.393
comGC	Staphylococcus aureus N315	48.837	80.374	0.393
comGC	Latilactobacillus sakei subsp. sakei 23K	45.349	80.374	0.364