Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   DQL12_RS10575 Genome accession   NZ_LS483450
Coordinates   1941933..1942235 (-) Length   100 a.a.
NCBI ID   WP_000413382.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 4041STDY6583227     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1936933..1947235
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL12_RS10545 rnpA 1937612..1937983 (-) 372 WP_044793385.1 ribonuclease P protein component -
  DQL12_RS12510 - 1938000..1938131 (-) 132 WP_000768904.1 hypothetical protein -
  DQL12_RS10550 - 1938132..1939322 (-) 1191 WP_000167765.1 acetate kinase -
  DQL12_RS10555 comYH 1939373..1940326 (-) 954 WP_050255606.1 class I SAM-dependent methyltransferase Machinery gene
  DQL12_RS10560 - 1940387..1940981 (-) 595 Protein_1953 class I SAM-dependent methyltransferase -
  DQL12_RS10565 comGG/cglG 1941118..1941531 (-) 414 WP_050255604.1 competence type IV pilus minor pilin ComGG Machinery gene
  DQL12_RS10570 comGF/cglF 1941509..1941970 (-) 462 WP_000250520.1 competence type IV pilus minor pilin ComGF Machinery gene
  DQL12_RS10575 comGE/cglE 1941933..1942235 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  DQL12_RS10580 comGD/cglD 1942198..1942632 (-) 435 WP_033606693.1 competence type IV pilus minor pilin ComGD Machinery gene
  DQL12_RS10585 comGC/cglC 1942595..1942918 (-) 324 WP_000738628.1 comG operon protein ComGC Machinery gene
  DQL12_RS10590 comGB/cglB 1942920..1943936 (-) 1017 WP_077141332.1 competence type IV pilus assembly protein ComGB Machinery gene
  DQL12_RS10595 comGA/cglA/cilD 1943884..1944825 (-) 942 WP_000249550.1 competence type IV pilus ATPase ComGA Machinery gene
  DQL12_RS10600 - 1944901..1945266 (-) 366 WP_000286415.1 DUF1033 family protein -
  DQL12_RS10605 - 1945417..1946475 (-) 1059 WP_001861944.1 zinc-dependent alcohol dehydrogenase family protein -

Sequence

Protein


Download         Length: 100 a.a.        Molecular weight: 11108.08 Da        Isoelectric Point: 9.7273

>NTDB_id=1142011 DQL12_RS10575 WP_000413382.1 1941933..1942235(-) (comGE/cglE) [Streptococcus pneumoniae strain 4041STDY6583227]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVSINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide


Download         Length: 303 bp        

>NTDB_id=1142011 DQL12_RS10575 WP_000413382.1 1941933..1942235(-) (comGE/cglE) [Streptococcus pneumoniae strain 4041STDY6583227]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCTTGCAGACGGGGCAAAATCAGGTAAGCATCAACGGAGTTGAGATTCAGGTATTTTCT
AGTGAAAAAGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(16-97)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus pneumoniae Rx1

100

100

1
  comGE/cglE Streptococcus pneumoniae D39

100

100

1
  comGE/cglE Streptococcus pneumoniae R6

100

100

1
  comGE/cglE Streptococcus pneumoniae TIGR4

100

100

1
  comGE/cglE Streptococcus mitis NCTC 12261

98

100

0.98
  comGE/cglE Streptococcus mitis SK321

98

100

0.98
  comYE Streptococcus mutans UA140

44.444

90

0.4
  comYE Streptococcus mutans UA159

44.444

90

0.4

Multiple sequence alignment