Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGF/cglF   Type   Machinery gene
Locus tag   DQL12_RS10570 Genome accession   NZ_LS483450
Coordinates   1941509..1941970 (-) Length   153 a.a.
NCBI ID   WP_000250520.1    Uniprot ID   C1CA95
Organism   Streptococcus pneumoniae strain 4041STDY6583227     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1936509..1946970
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL12_RS10540 - 1936813..1937637 (-) 825 WP_000727904.1 membrane protein insertase YidC -
  DQL12_RS10545 rnpA 1937612..1937983 (-) 372 WP_044793385.1 ribonuclease P protein component -
  DQL12_RS12510 - 1938000..1938131 (-) 132 WP_000768904.1 hypothetical protein -
  DQL12_RS10550 - 1938132..1939322 (-) 1191 WP_000167765.1 acetate kinase -
  DQL12_RS10555 comYH 1939373..1940326 (-) 954 WP_050255606.1 class I SAM-dependent methyltransferase Machinery gene
  DQL12_RS10560 - 1940387..1940981 (-) 595 Protein_1953 class I SAM-dependent methyltransferase -
  DQL12_RS10565 comGG/cglG 1941118..1941531 (-) 414 WP_050255604.1 competence type IV pilus minor pilin ComGG Machinery gene
  DQL12_RS10570 comGF/cglF 1941509..1941970 (-) 462 WP_000250520.1 competence type IV pilus minor pilin ComGF Machinery gene
  DQL12_RS10575 comGE/cglE 1941933..1942235 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  DQL12_RS10580 comGD/cglD 1942198..1942632 (-) 435 WP_033606693.1 competence type IV pilus minor pilin ComGD Machinery gene
  DQL12_RS10585 comGC/cglC 1942595..1942918 (-) 324 WP_000738628.1 comG operon protein ComGC Machinery gene
  DQL12_RS10590 comGB/cglB 1942920..1943936 (-) 1017 WP_077141332.1 competence type IV pilus assembly protein ComGB Machinery gene
  DQL12_RS10595 comGA/cglA/cilD 1943884..1944825 (-) 942 WP_000249550.1 competence type IV pilus ATPase ComGA Machinery gene
  DQL12_RS10600 - 1944901..1945266 (-) 366 WP_000286415.1 DUF1033 family protein -
  DQL12_RS10605 - 1945417..1946475 (-) 1059 WP_001861944.1 zinc-dependent alcohol dehydrogenase family protein -

Sequence

Protein


Download         Length: 153 a.a.        Molecular weight: 17905.50 Da        Isoelectric Point: 8.0031

>NTDB_id=1142010 DQL12_RS10570 WP_000250520.1 1941509..1941970(-) (comGF/cglF) [Streptococcus pneumoniae strain 4041STDY6583227]
MVQNSCWQSKSHKVKAFTLLESLIALIVISGGLLLFQAMSQLLISEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGN
RLYMKQDGKEIAMGKSKADDFRKTNARGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES

Nucleotide


Download         Length: 462 bp        

>NTDB_id=1142010 DQL12_RS10570 WP_000250520.1 1941509..1941970(-) (comGF/cglF) [Streptococcus pneumoniae strain 4041STDY6583227]
ATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAAGGTCAAGGCTTTTACCTTGTTAGAATCCCTGATTGCCCTGAT
TGTCATCAGTGGGGGATTACTCCTTTTTCAAGCTATGAGTCAGCTCCTCATTTCAGAAGTTCGCTACCAGCAACAAAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGGACCAACTTGAGGCAGAATTAGACCGTTCGCAGTTCGAAAAAGTAGAAGGCAAT
CGCCTATACATGAAGCAAGATGGCAAGGAGATTGCTATGGGTAAGTCTAAGGCAGATGATTTCCGTAAAACGAATGCTCG
TGGTCGAGGTTATCAGCCTATGGTTTATGGCCTCAAATCAGCTCAGATTACAGAGGACAATCAACTGGTTCATTTTCGTT
TCCAGTTTCAAAAAGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGAAGAAAGTTAA

Domains

Predicted by InterproScan.

Putative Competence protein ComGF (ComGF)

(45-141)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB C1CA95

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGF/cglF Streptococcus pneumoniae Rx1

93.464

100

0.935
  comGF/cglF Streptococcus pneumoniae D39

93.464

100

0.935
  comGF/cglF Streptococcus pneumoniae R6

93.464

100

0.935
  comGF/cglF Streptococcus pneumoniae TIGR4

93.464

100

0.935
  comGF/cglF Streptococcus mitis NCTC 12261

90.85

100

0.909
  comGF/cglF Streptococcus mitis SK321

90.85

100

0.909

Multiple sequence alignment