Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA/cglA/cilD   Type   Machinery gene
Locus tag   DQL12_RS10595 Genome accession   NZ_LS483450
Coordinates   1943884..1944825 (-) Length   313 a.a.
NCBI ID   WP_000249550.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 4041STDY6583227     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1938884..1949825
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL12_RS10555 comYH 1939373..1940326 (-) 954 WP_050255606.1 class I SAM-dependent methyltransferase Machinery gene
  DQL12_RS10560 - 1940387..1940981 (-) 595 Protein_1953 class I SAM-dependent methyltransferase -
  DQL12_RS10565 comGG/cglG 1941118..1941531 (-) 414 WP_050255604.1 competence type IV pilus minor pilin ComGG Machinery gene
  DQL12_RS10570 comGF/cglF 1941509..1941970 (-) 462 WP_000250520.1 competence type IV pilus minor pilin ComGF Machinery gene
  DQL12_RS10575 comGE/cglE 1941933..1942235 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  DQL12_RS10580 comGD/cglD 1942198..1942632 (-) 435 WP_033606693.1 competence type IV pilus minor pilin ComGD Machinery gene
  DQL12_RS10585 comGC/cglC 1942595..1942918 (-) 324 WP_000738628.1 comG operon protein ComGC Machinery gene
  DQL12_RS10590 comGB/cglB 1942920..1943936 (-) 1017 WP_077141332.1 competence type IV pilus assembly protein ComGB Machinery gene
  DQL12_RS10595 comGA/cglA/cilD 1943884..1944825 (-) 942 WP_000249550.1 competence type IV pilus ATPase ComGA Machinery gene
  DQL12_RS10600 - 1944901..1945266 (-) 366 WP_000286415.1 DUF1033 family protein -
  DQL12_RS10605 - 1945417..1946475 (-) 1059 WP_001861944.1 zinc-dependent alcohol dehydrogenase family protein -
  DQL12_RS10610 nagA 1946638..1947789 (-) 1152 WP_001134457.1 N-acetylglucosamine-6-phosphate deacetylase -
  DQL12_RS10615 - 1947942..1949759 (-) 1818 WP_042516253.1 acyltransferase family protein -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35516.43 Da        Isoelectric Point: 6.0083

>NTDB_id=1142015 DQL12_RS10595 WP_000249550.1 1943884..1944825(-) (comGA/cglA/cilD) [Streptococcus pneumoniae strain 4041STDY6583227]
MVQEIAQEIIRSARKKGAQDIYFVPKLDAYELHMRVGDERCKIGSYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYA
YDQKIASLRLSTVGDYRGHESLVIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVVRASLTGATVFSTIHAKSIRGVY
ERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFASRDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS

Nucleotide


Download         Length: 942 bp        

>NTDB_id=1142015 DQL12_RS10595 WP_000249550.1 1943884..1944825(-) (comGA/cglA/cilD) [Streptococcus pneumoniae strain 4041STDY6583227]
ATGGTTCAAGAAATTGCACAAGAAATCATTCGTTCGGCTCGGAAAAAAGGGGCGCAAGACATTTATTTTGTCCCTAAGTT
AGATGCCTATGAGCTTCATATGAGGGTAGGAGACGAGCGCTGTAAAATTGGTAGCTATGATTTTGAAAAGTTTGCAGCCG
TTATCAGTCACTTTAAGTTTGTGGCGGGTATGAATGTGGGAGAAAAAAGACGTAGTCAACTGGGTTCCTGTGATTATGCC
TATGACCAGAAGATAGCGTCTCTACGTTTATCTACTGTAGGCGATTATCGGGGGCATGAGAGTTTGGTTATCCGTTTGTT
GCACGATGAGGAGCAGGACTTGCATTTTTGGTTTCAGGATATTGAAGAATTAGGCAAGCAGTACAGGCAACGGGGACTCT
ATCTTTTTGCTGGTCCGGTTGGGAGTGGTAAGACGACCTTGATGCATGAATTGTCCAAGTCACTCTTTAAAGGACAGCAA
GTTATGTCCATCGAAGATCCTGTCGAAATCAAGCAGGACGACATGCTTCAGTTGCAGTTGAACGAAGCAATCGGCCTAAC
CTATGAAAATCTAATCAAACTTTCCTTGCGTCATCGACCAGATCTCTTGATTATCGGAGAAATTCGTGACAGCGAGACGG
CGCGTGCAGTGGTCAGAGCTAGTTTGACAGGTGCGACAGTCTTTTCAACCATTCACGCCAAAAGTATCCGAGGTGTTTAT
GAGCGTCTGCTGGAGTTGGGTGTGAGTGAAGAAGAATTGGCAGTTGTTCTGCAAGGAGTCTGCTACCAGAGATTAATCGG
GGGAGGAGGAATCGTTGACTTTGCAAGCAGAGATTATCAAGAACACCAAGCAGCCAAGTGGAATGAGCAAATTGACCAGC
TTCTTAAAGATGGACATATCACAAGTCTTCAGGCTGAGACGGAAAAAATTAGCTACAGCTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

99.361

100

0.994
  comGA/cglA/cilD Streptococcus pneumoniae D39

99.361

100

0.994
  comGA/cglA/cilD Streptococcus pneumoniae R6

99.361

100

0.994
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

99.361

100

0.994
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

96.486

100

0.965
  comYA Streptococcus gordonii str. Challis substr. CH1

78.387

99.042

0.776
  comYA Streptococcus mutans UA159

66.238

99.361

0.658
  comYA Streptococcus mutans UA140

66.238

99.361

0.658
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

62.903

99.042

0.623
  comGA Lactococcus lactis subsp. cremoris KW2

55.128

99.681

0.55
  comGA Latilactobacillus sakei subsp. sakei 23K

41.912

86.901

0.364

Multiple sequence alignment