Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB/cglB   Type   Machinery gene
Locus tag   DQL12_RS10590 Genome accession   NZ_LS483450
Coordinates   1942920..1943936 (-) Length   338 a.a.
NCBI ID   WP_077141332.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 4041STDY6583227     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1937920..1948936
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL12_RS12510 - 1938000..1938131 (-) 132 WP_000768904.1 hypothetical protein -
  DQL12_RS10550 - 1938132..1939322 (-) 1191 WP_000167765.1 acetate kinase -
  DQL12_RS10555 comYH 1939373..1940326 (-) 954 WP_050255606.1 class I SAM-dependent methyltransferase Machinery gene
  DQL12_RS10560 - 1940387..1940981 (-) 595 Protein_1953 class I SAM-dependent methyltransferase -
  DQL12_RS10565 comGG/cglG 1941118..1941531 (-) 414 WP_050255604.1 competence type IV pilus minor pilin ComGG Machinery gene
  DQL12_RS10570 comGF/cglF 1941509..1941970 (-) 462 WP_000250520.1 competence type IV pilus minor pilin ComGF Machinery gene
  DQL12_RS10575 comGE/cglE 1941933..1942235 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  DQL12_RS10580 comGD/cglD 1942198..1942632 (-) 435 WP_033606693.1 competence type IV pilus minor pilin ComGD Machinery gene
  DQL12_RS10585 comGC/cglC 1942595..1942918 (-) 324 WP_000738628.1 comG operon protein ComGC Machinery gene
  DQL12_RS10590 comGB/cglB 1942920..1943936 (-) 1017 WP_077141332.1 competence type IV pilus assembly protein ComGB Machinery gene
  DQL12_RS10595 comGA/cglA/cilD 1943884..1944825 (-) 942 WP_000249550.1 competence type IV pilus ATPase ComGA Machinery gene
  DQL12_RS10600 - 1944901..1945266 (-) 366 WP_000286415.1 DUF1033 family protein -
  DQL12_RS10605 - 1945417..1946475 (-) 1059 WP_001861944.1 zinc-dependent alcohol dehydrogenase family protein -
  DQL12_RS10610 nagA 1946638..1947789 (-) 1152 WP_001134457.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence

Protein


Download         Length: 338 a.a.        Molecular weight: 38466.48 Da        Isoelectric Point: 9.6162

>NTDB_id=1142014 DQL12_RS10590 WP_077141332.1 1942920..1943936(-) (comGB/cglB) [Streptococcus pneumoniae strain 4041STDY6583227]
MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLDRSALLDKQCVTQMRTGLSQGKSFSEMMESLGCSSTI
VTQLSLAEVHGNLHLSLGKIEEYLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQGMELTQIFQMMQEQGSQLFKEI
GQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGEVKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIV
LLYAAMLMPMYQNMEVNF

Nucleotide


Download         Length: 1017 bp        

>NTDB_id=1142014 DQL12_RS10590 WP_077141332.1 1942920..1943936(-) (comGB/cglB) [Streptococcus pneumoniae strain 4041STDY6583227]
ATGGACATATCACAAGTCTTCAGGCTGAGACGGAAAAAATTAGCTACAGCTAAGCAAAAAAATATCATCACCCTATTTAA
CAATCTCTTTTCTAGCGGTTTTCATCTGGTGGAGACCATCTCCTTTTTAGATAGGAGTGCTTTGTTGGACAAGCAGTGTG
TGACCCAGATGCGTACAGGCTTGTCTCAGGGGAAATCATTCTCAGAAATGATGGAAAGTTTGGGATGTTCAAGTACCATT
GTCACTCAGTTATCTCTAGCTGAAGTTCATGGCAATCTTCACCTGAGTTTGGGAAAGATAGAAGAATATCTAGACAATCT
GGCCAAGGTCAAGAAAAAGTTAATTGAAGTAGCGACCTATCCTTTGATTTTGCTGGGTTTTCTTCTCTTAATTATGCTGG
GGCTACGGAATTACCTGCTCCCACAACTGGATAGTAGCAATATTGCCACCCGAATTATCGGTAATCTGCCACAAATTTTT
CTAGGCATGGTAGGGCTTGTTTCCGTGCTTGCCCTTTTAGCACTAACTTTTTATAAAAGAAGTTCTAAGATGAGTGTCTT
TTCTATCTTAGCACGCCTTCCCTTTATTGGAATCTTTGTGCAGACCTACTTGACAGCCTATTATGCACGTGAATGGGGGA
ATATGATTTCACAGGGAATGGAGCTGACGCAGATTTTTCAAATGATGCAGGAACAAGGTTCCCAGCTCTTTAAAGAAATC
GGTCAAGATCTGGCTCAAACCCTGAAAAATGGCCGTGAATTTTCTCAGACGATAGGAACCTATCCTTTCTTTAGGAAGGA
ATTGAGTCTCATCATAGAGTATGGGGAAGTTAAGTCCAAGCTGGGTAGTGAGTTGGAAATCTATGCTGAAAAAACTTGGG
AAGCCTTTTTTACCCGAGTCAACCGCACCATGAATTTGGTGCAGCCACTGGTTTTTATCTTTGTGGCACTGATTATCGTT
TTACTTTATGCGGCAATGCTCATGCCCATGTATCAAAATATGGAGGTAAATTTTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(24-141)

Type II secretion system (T2SS), protein F (T2SSF)

(209-329)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB/cglB Streptococcus pneumoniae Rx1

98.817

100

0.988
  comGB/cglB Streptococcus pneumoniae D39

98.817

100

0.988
  comGB/cglB Streptococcus pneumoniae R6

98.817

100

0.988
  comGB/cglB Streptococcus pneumoniae TIGR4

98.817

100

0.988
  comGB/cglB Streptococcus mitis SK321

95.266

100

0.953
  comGB/cglB Streptococcus mitis NCTC 12261

94.379

100

0.944
  comYB Streptococcus gordonii str. Challis substr. CH1

70.833

99.408

0.704
  comYB Streptococcus mutans UA140

58.176

94.083

0.547
  comYB Streptococcus mutans UA159

58.176

94.083

0.547
  comGB Lactococcus lactis subsp. cremoris KW2

50.898

98.817

0.503

Multiple sequence alignment