Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC/cglC   Type   Machinery gene
Locus tag   E0F39_RS10680 Genome accession   NZ_LR216060
Coordinates   1965571..1965897 (-) Length   108 a.a.
NCBI ID   WP_001864566.1    Uniprot ID   A0AAJ5TKH0
Organism   Streptococcus pneumoniae strain GPSC47 substr. ST315     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1960571..1970897
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E0F39_RS10640 (SAMEA3713867_02011) rnpA 1960588..1960959 (-) 372 WP_000739246.1 ribonuclease P protein component -
  E0F39_RS13080 - 1960976..1961107 (-) 132 WP_000768904.1 hypothetical protein -
  E0F39_RS10645 (SAMEA3713867_02012) - 1961108..1962298 (-) 1191 WP_001864575.1 acetate kinase -
  E0F39_RS10650 (SAMEA3713867_02013) comYH 1962349..1963302 (-) 954 WP_050199051.1 class I SAM-dependent methyltransferase Machinery gene
  E0F39_RS10655 - 1963363..1963957 (-) 595 Protein_2015 class I SAM-dependent methyltransferase -
  E0F39_RS10660 (SAMEA3713867_02016) comGG/cglG 1964094..1964507 (-) 414 WP_001864570.1 competence type IV pilus minor pilin ComGG Machinery gene
  E0F39_RS10665 (SAMEA3713867_02017) comGF/cglF 1964485..1964946 (-) 462 WP_001864569.1 competence type IV pilus minor pilin ComGF Machinery gene
  E0F39_RS10670 (SAMEA3713867_02018) comGE/cglE 1964909..1965211 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  E0F39_RS10675 (SAMEA3713867_02019) comGD/cglD 1965174..1965578 (-) 405 WP_001864568.1 competence type IV pilus minor pilin ComGD Machinery gene
  E0F39_RS10680 (SAMEA3713867_02020) comGC/cglC 1965571..1965897 (-) 327 WP_001864566.1 comG operon protein ComGC Machinery gene
  E0F39_RS10685 (SAMEA3713867_02021) comGB/cglB 1965899..1966915 (-) 1017 WP_078133877.1 competence type IV pilus assembly protein ComGB Machinery gene
  E0F39_RS10690 (SAMEA3713867_02022) comGA/cglA/cilD 1966863..1967804 (-) 942 WP_001864563.1 competence type IV pilus ATPase ComGA Machinery gene
  E0F39_RS10695 (SAMEA3713867_02023) - 1967880..1968245 (-) 366 WP_000286415.1 DUF1033 family protein -
  E0F39_RS10700 (SAMEA3713867_02024) - 1968396..1969454 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -
  E0F39_RS10705 (SAMEA3713867_02025) nagA 1969617..1970768 (-) 1152 WP_001134457.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence

Protein


Download         Length: 108 a.a.        Molecular weight: 12149.29 Da        Isoelectric Point: 10.1001

>NTDB_id=1126221 E0F39_RS10680 WP_001864566.1 1965571..1965897(-) (comGC/cglC) [Streptococcus pneumoniae strain GPSC47 substr. ST315]
MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLEKNEDASLSKLKD
DGRITEEQAKAYKEHHDKNGGANRKVND

Nucleotide


Download         Length: 327 bp        

>NTDB_id=1126221 E0F39_RS10680 WP_001864566.1 1965571..1965897(-) (comGC/cglC) [Streptococcus pneumoniae strain GPSC47 substr. ST315]
ATGAAAAAAATGATGACATTCTTGAAAAAAGCTAAGGTTAAAGCTTTTACATTGGTGGAAATGTTGGTGGTCTTGCTGAT
TATCAGCGTGCTTTTCTTGCTCTTTGTACCTAATCTGACCAAGCAAAAAGAAGCAGTCAATGACAAAGGAAAAGCAGCTG
TTGTTAAGGTGGTGGAAAGCCAGGCAGAACTTTATAGCTTGGAAAAGAATGAAGATGCTAGCCTAAGCAAGTTAAAAGAC
GATGGACGCATCACGGAAGAACAGGCTAAAGCTTATAAAGAACACCATGATAAAAATGGAGGAGCAAATCGTAAAGTCAA
TGATTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(11-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus pneumoniae Rx1

96.296

100

0.963
  comGC/cglC Streptococcus pneumoniae D39

96.296

100

0.963
  comGC/cglC Streptococcus pneumoniae R6

96.296

100

0.963
  comGC/cglC Streptococcus pneumoniae TIGR4

95.37

100

0.954
  comGC/cglC Streptococcus mitis SK321

92.593

100

0.926
  comGC/cglC Streptococcus mitis NCTC 12261

90.196

94.444

0.852
  comYC Streptococcus gordonii str. Challis substr. CH1

66.99

95.37

0.639
  comYC Streptococcus mutans UA159

61.765

94.444

0.583
  comYC Streptococcus mutans UA140

61.765

94.444

0.583
  comGC Lactococcus lactis subsp. cremoris KW2

53.922

94.444

0.509
  comYC Streptococcus suis isolate S10

67.901

75

0.509
  comGC Staphylococcus aureus MW2

48.837

79.63

0.389
  comGC Staphylococcus aureus N315

48.837

79.63

0.389
  comGC Latilactobacillus sakei subsp. sakei 23K

45.349

79.63

0.361

Multiple sequence alignment