Detailed information NTG1126219

Bioinformatically predicted

Overview

• Name: comGE/cglE
• Type: Machinery gene
• Locus tag: E0F39_RS10670
• Genome accession: NZ_LR216060
• Coordinates: 1964909..1965211 (-)
• Length: 100 a.a.
• NCBI ID: WP_000413382.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain GPSC47 substr. ST315
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1959909..1970211

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E0F39_RS10640 (SAMEA3713867_02011)	rnpA	1960588..1960959 (-)	372	WP_000739246.1	ribonuclease P protein component	-
E0F39_RS13080	-	1960976..1961107 (-)	132	WP_000768904.1	hypothetical protein	-
E0F39_RS10645 (SAMEA3713867_02012)	-	1961108..1962298 (-)	1191	WP_001864575.1	acetate kinase	-
E0F39_RS10650 (SAMEA3713867_02013)	comYH	1962349..1963302 (-)	954	WP_050199051.1	class I SAM-dependent methyltransferase	Machinery gene
E0F39_RS10655	-	1963363..1963957 (-)	595	Protein_2015	class I SAM-dependent methyltransferase	-
E0F39_RS10660 (SAMEA3713867_02016)	comGG/cglG	1964094..1964507 (-)	414	WP_001864570.1	competence type IV pilus minor pilin ComGG	Machinery gene
E0F39_RS10665 (SAMEA3713867_02017)	comGF/cglF	1964485..1964946 (-)	462	WP_001864569.1	competence type IV pilus minor pilin ComGF	Machinery gene
E0F39_RS10670 (SAMEA3713867_02018)	comGE/cglE	1964909..1965211 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
E0F39_RS10675 (SAMEA3713867_02019)	comGD/cglD	1965174..1965578 (-)	405	WP_001864568.1	competence type IV pilus minor pilin ComGD	Machinery gene
E0F39_RS10680 (SAMEA3713867_02020)	comGC/cglC	1965571..1965897 (-)	327	WP_001864566.1	comG operon protein ComGC	Machinery gene
E0F39_RS10685 (SAMEA3713867_02021)	comGB/cglB	1965899..1966915 (-)	1017	WP_078133877.1	competence type IV pilus assembly protein ComGB	Machinery gene
E0F39_RS10690 (SAMEA3713867_02022)	comGA/cglA/cilD	1966863..1967804 (-)	942	WP_001864563.1	competence type IV pilus ATPase ComGA	Machinery gene
E0F39_RS10695 (SAMEA3713867_02023)	-	1967880..1968245 (-)	366	WP_000286415.1	DUF1033 family protein	-
E0F39_RS10700 (SAMEA3713867_02024)	-	1968396..1969454 (-)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 100 a.a.
• Molecular weight: 11108.08 Da
• Isoelectric Point: 9.7273

>NTDB_id=1126219 E0F39_RS10670 WP_000413382.1 1964909..1965211(-) (comGE/cglE) [Streptococcus pneumoniae strain GPSC47 substr. ST315]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVSINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide

• Length: 303 bp

>NTDB_id=1126219 E0F39_RS10670 WP_000413382.1 1964909..1965211(-) (comGE/cglE) [Streptococcus pneumoniae strain GPSC47 substr. ST315]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCCTGCAGACGGGGCAAAATCAGGTAAGCATCAACGGAGTTGAGATTCAGGTATTTTCT
AGTGAAAAAGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

• Type II secretory pathway pseudopilin (ComGE) (16-97)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGE/cglE	Streptococcus pneumoniae Rx1	100	100	1
comGE/cglE	Streptococcus pneumoniae D39	100	100	1
comGE/cglE	Streptococcus pneumoniae R6	100	100	1
comGE/cglE	Streptococcus pneumoniae TIGR4	100	100	1
comGE/cglE	Streptococcus mitis NCTC 12261	98	100	0.98
comGE/cglE	Streptococcus mitis SK321	98	100	0.98
comYE	Streptococcus mutans UA140	44.444	90	0.4
comYE	Streptococcus mutans UA159	44.444	90	0.4