Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGD/cglD   Type   Machinery gene
Locus tag   E0F39_RS10675 Genome accession   NZ_LR216060
Coordinates   1965174..1965578 (-) Length   134 a.a.
NCBI ID   WP_001864568.1    Uniprot ID   A0A0T8D4A4
Organism   Streptococcus pneumoniae strain GPSC47 substr. ST315     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1960174..1970578
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E0F39_RS10640 (SAMEA3713867_02011) rnpA 1960588..1960959 (-) 372 WP_000739246.1 ribonuclease P protein component -
  E0F39_RS13080 - 1960976..1961107 (-) 132 WP_000768904.1 hypothetical protein -
  E0F39_RS10645 (SAMEA3713867_02012) - 1961108..1962298 (-) 1191 WP_001864575.1 acetate kinase -
  E0F39_RS10650 (SAMEA3713867_02013) comYH 1962349..1963302 (-) 954 WP_050199051.1 class I SAM-dependent methyltransferase Machinery gene
  E0F39_RS10655 - 1963363..1963957 (-) 595 Protein_2015 class I SAM-dependent methyltransferase -
  E0F39_RS10660 (SAMEA3713867_02016) comGG/cglG 1964094..1964507 (-) 414 WP_001864570.1 competence type IV pilus minor pilin ComGG Machinery gene
  E0F39_RS10665 (SAMEA3713867_02017) comGF/cglF 1964485..1964946 (-) 462 WP_001864569.1 competence type IV pilus minor pilin ComGF Machinery gene
  E0F39_RS10670 (SAMEA3713867_02018) comGE/cglE 1964909..1965211 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  E0F39_RS10675 (SAMEA3713867_02019) comGD/cglD 1965174..1965578 (-) 405 WP_001864568.1 competence type IV pilus minor pilin ComGD Machinery gene
  E0F39_RS10680 (SAMEA3713867_02020) comGC/cglC 1965571..1965897 (-) 327 WP_001864566.1 comG operon protein ComGC Machinery gene
  E0F39_RS10685 (SAMEA3713867_02021) comGB/cglB 1965899..1966915 (-) 1017 WP_078133877.1 competence type IV pilus assembly protein ComGB Machinery gene
  E0F39_RS10690 (SAMEA3713867_02022) comGA/cglA/cilD 1966863..1967804 (-) 942 WP_001864563.1 competence type IV pilus ATPase ComGA Machinery gene
  E0F39_RS10695 (SAMEA3713867_02023) - 1967880..1968245 (-) 366 WP_000286415.1 DUF1033 family protein -
  E0F39_RS10700 (SAMEA3713867_02024) - 1968396..1969454 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -

Sequence

Protein


Download         Length: 134 a.a.        Molecular weight: 14664.92 Da        Isoelectric Point: 10.2164

>NTDB_id=1126220 E0F39_RS10675 WP_001864568.1 1965174..1965578(-) (comGD/cglD) [Streptococcus pneumoniae strain GPSC47 substr. ST315]
MIKAFTMLESLLVLGLVSILALGLSGSVQSTFAAVEEQIFFMEFEELYRETQKRSVASQQKTSLNLDGQMISNGSQKLPV
PKGIQAPSGQSITFDRAGGNSSLAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN

Nucleotide


Download         Length: 405 bp        

>NTDB_id=1126220 E0F39_RS10675 WP_001864568.1 1965174..1965578(-) (comGD/cglD) [Streptococcus pneumoniae strain GPSC47 substr. ST315]
ATGATTAAGGCCTTTACCATGCTGGAAAGTCTCTTGGTTTTGGGTCTTGTGAGTATCCTTGCCTTGGGCTTGTCCGGCTC
TGTCCAGTCCACTTTTGCAGCGGTAGAGGAACAGATTTTCTTTATGGAGTTTGAAGAACTCTATCGGGAAACCCAAAAAC
GCAGTGTAGCTAGTCAACAAAAGACTAGTCTGAACTTGGATGGGCAGATGATTAGCAATGGCAGTCAAAAGTTGCCAGTT
CCTAAAGGAATTCAGGCACCATCAGGCCAAAGTATTACATTTGACCGAGCTGGGGGCAATTCGTCCCTGGCTAAGGTTGA
ATTTCAGACCAGTAAAGGAGCGATTCGCTATCAATTATATCTAGGAAATGGAAAAATTAAACGCATTAAGGAAACAAAAA
ATTAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0T8D4A4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGD/cglD Streptococcus pneumoniae Rx1

98.507

100

0.985
  comGD/cglD Streptococcus pneumoniae D39

98.507

100

0.985
  comGD/cglD Streptococcus pneumoniae R6

98.507

100

0.985
  comGD/cglD Streptococcus pneumoniae TIGR4

97.761

100

0.978
  comGD/cglD Streptococcus mitis SK321

96.269

100

0.963
  comGD/cglD Streptococcus mitis NCTC 12261

96.992

99.254

0.963
  comYD Streptococcus gordonii str. Challis substr. CH1

59.843

94.776

0.567
  comYD Streptococcus mutans UA140

50

95.522

0.478
  comYD Streptococcus mutans UA159

50

95.522

0.478

Multiple sequence alignment