Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   E0F39_RS10650 Genome accession   NZ_LR216060
Coordinates   1962349..1963302 (-) Length   317 a.a.
NCBI ID   WP_050199051.1    Uniprot ID   A0A0T8UGP7
Organism   Streptococcus pneumoniae strain GPSC47 substr. ST315     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1957349..1968302
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E0F39_RS10625 (SAMEA3713867_02008) - 1958110..1958733 (-) 624 WP_000932635.1 hypothetical protein -
  E0F39_RS10630 (SAMEA3713867_02009) jag 1958784..1959770 (-) 987 WP_000260021.1 RNA-binding cell elongation regulator Jag/EloR -
  E0F39_RS10635 (SAMEA3713867_02010) - 1959789..1960613 (-) 825 WP_201417385.1 membrane protein insertase YidC -
  E0F39_RS10640 (SAMEA3713867_02011) rnpA 1960588..1960959 (-) 372 WP_000739246.1 ribonuclease P protein component -
  E0F39_RS13080 - 1960976..1961107 (-) 132 WP_000768904.1 hypothetical protein -
  E0F39_RS10645 (SAMEA3713867_02012) - 1961108..1962298 (-) 1191 WP_001864575.1 acetate kinase -
  E0F39_RS10650 (SAMEA3713867_02013) comYH 1962349..1963302 (-) 954 WP_050199051.1 class I SAM-dependent methyltransferase Machinery gene
  E0F39_RS10655 - 1963363..1963957 (-) 595 Protein_2015 class I SAM-dependent methyltransferase -
  E0F39_RS10660 (SAMEA3713867_02016) comGG/cglG 1964094..1964507 (-) 414 WP_001864570.1 competence type IV pilus minor pilin ComGG Machinery gene
  E0F39_RS10665 (SAMEA3713867_02017) comGF/cglF 1964485..1964946 (-) 462 WP_001864569.1 competence type IV pilus minor pilin ComGF Machinery gene
  E0F39_RS10670 (SAMEA3713867_02018) comGE/cglE 1964909..1965211 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  E0F39_RS10675 (SAMEA3713867_02019) comGD/cglD 1965174..1965578 (-) 405 WP_001864568.1 competence type IV pilus minor pilin ComGD Machinery gene
  E0F39_RS10680 (SAMEA3713867_02020) comGC/cglC 1965571..1965897 (-) 327 WP_001864566.1 comG operon protein ComGC Machinery gene
  E0F39_RS10685 (SAMEA3713867_02021) comGB/cglB 1965899..1966915 (-) 1017 WP_078133877.1 competence type IV pilus assembly protein ComGB Machinery gene
  E0F39_RS10690 (SAMEA3713867_02022) comGA/cglA/cilD 1966863..1967804 (-) 942 WP_001864563.1 competence type IV pilus ATPase ComGA Machinery gene
  E0F39_RS10695 (SAMEA3713867_02023) - 1967880..1968245 (-) 366 WP_000286415.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35726.92 Da        Isoelectric Point: 4.2434

>NTDB_id=1126216 E0F39_RS10650 WP_050199051.1 1962349..1963302(-) (comYH) [Streptococcus pneumoniae strain GPSC47 substr. ST315]
MDFEKIEQAYIYLLENVQVIQSDLATNFYDALVEQNSIYLDGETELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQT
EPLQANHQFTPDAIALLLVFIVEELFKEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGLKYLKSDGYAIFLAPSDLLTSPQ
SDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFILQKKNEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI

Nucleotide


Download         Length: 954 bp        

>NTDB_id=1126216 E0F39_RS10650 WP_050199051.1 1962349..1963302(-) (comYH) [Streptococcus pneumoniae strain GPSC47 substr. ST315]
ATGGATTTTGAAAAAATTGAACAAGCTTATATCTATTTACTAGAGAATGTCCAAGTCATCCAAAGTGATTTGGCGACCAA
CTTTTATGACGCCTTGGTGGAGCAAAATAGCATCTATCTGGATGGTGAAACTGAGCTAAACCAGGTCAAAGACAACAATC
AGGCCCTTAAGCGTTTAGCACTACGCAAAGAAGAATGGCTCAAGACCTACCAGTTTCTCTTGATGAAGGCTGGGCAAACA
GAACCCTTGCAGGCCAATCACCAGTTTACGCCAGATGCTATTGCCTTACTTTTGGTATTTATTGTGGAAGAGTTGTTTAA
AGAGGAGGAAATTACTATCCTCGAAATGGGTTCTGGGATGGGAATTCTAGGCGCTACTTTCTTGACCTCGCTTGATAAAA
AGGTGGATTACTTGGGAATGGAAGTGGATGATTTACTGATTGATCTGGCAGCTAGCATGGCAGATGTAATTGGTTTGCAG
GCTGGCTTTGTCCAAGGAGATGCCGTTCGTCCACAAATGCTCAAAGAAAGCGATGTGGTCATCAGTGACTTGCCTGTTGG
CTATTATCCTGATGATGCCGTTGCGTCGCGCCATCAAGTTGCTTCTAGCCAAGAACATACTTACGCCCATCACTTGCTCA
TGGAACAAGGGCTTAAGTACCTCAAGTCAGACGGATACGCTATTTTTCTAGCTCCGAGTGATTTGTTGACCAGTCCTCAA
AGTGATTTGTTAAAAGAATGGCTGAAAGAAGAGGCGAGTCTGGTTGCTATGATTAGTCTGCCTGAAAACCTCTTTGCTAA
TGCCAAACAATCTAAGACTATTTTTATCTTACAGAAGAAAAATGAAATAGCAGTAGAGCCTTTTGTTTATCCACTTGCTA
GCTTGCAAGATGCAAGTGTTTTAATGAAATTTAAAGAAAATTTTCAAAAATGGACTCAAGGTACTGAAATATAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-282)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0T8UGP7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

54.633

98.738

0.539
  comYH Streptococcus mutans UA159

54.313

98.738

0.536

Multiple sequence alignment