Detailed information NTG1117843

Bioinformatically predicted

Overview

• Name: comYC
• Type: Machinery gene
• Locus tag: ELZ47_RS10780
• Genome accession: NZ_LR134002
• Coordinates: 2169133..2169450 (-)
• Length: 105 a.a.
• NCBI ID: WP_002896769.1
• Uniprot ID: F3SKF6
• Organism: Streptococcus sanguinis strain NCTC 10904
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2164133..2174450

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ELZ47_RS10745 (NCTC10904_02112)	-	2164516..2165265 (-)	750	WP_164549614.1	CPBP family intramembrane glutamic endopeptidase	-
ELZ47_RS10750 (NCTC10904_02113)	-	2165409..2166602 (-)	1194	WP_126435999.1	acetate kinase	-
ELZ47_RS10755 (NCTC10904_02114)	comYH	2166639..2167604 (-)	966	WP_126436000.1	class I SAM-dependent methyltransferase	Machinery gene
ELZ47_RS10760 (NCTC10904_02115)	comGG	2167686..2168078 (-)	393	WP_126436001.1	competence type IV pilus minor pilin ComGG	-
ELZ47_RS10765 (NCTC10904_02116)	comGF/cglF	2168059..2168496 (-)	438	WP_126436002.1	competence type IV pilus minor pilin ComGF	Machinery gene
ELZ47_RS10770 (NCTC10904_02117)	comGE/cglE	2168480..2168773 (-)	294	WP_126436003.1	competence type IV pilus minor pilin ComGE	Machinery gene
ELZ47_RS10775 (NCTC10904_02118)	comYD	2168739..2169173 (-)	435	WP_164549615.1	competence type IV pilus minor pilin ComGD	Machinery gene
ELZ47_RS10780 (NCTC10904_02119)	comYC	2169133..2169450 (-)	318	WP_002896769.1	competence type IV pilus major pilin ComGC	Machinery gene
ELZ47_RS10785 (NCTC10904_02120)	comYB	2169450..2170484 (-)	1035	WP_269460457.1	competence type IV pilus assembly protein ComGB	Machinery gene
ELZ47_RS10790 (NCTC10904_02121)	comYA	2170414..2171355 (-)	942	WP_126436006.1	competence type IV pilus ATPase ComGA	Machinery gene
ELZ47_RS10795 (NCTC10904_02122)	-	2171485..2171865 (-)	381	WP_126436007.1	DUF1033 family protein	-
ELZ47_RS10800 (NCTC10904_02123)	-	2172004..2173065 (-)	1062	WP_126436008.1	zinc-dependent alcohol dehydrogenase family protein	-
ELZ47_RS10805 (NCTC10904_02124)	-	2173236..2174342 (-)	1107	WP_002896776.1	glycosyl hydrolase family 8	-

Sequence

Protein

• Length: 105 a.a.
• Molecular weight: 11400.28 Da
• Isoelectric Point: 9.6959

>NTDB_id=1117843 ELZ47_RS10780 WP_002896769.1 2169133..2169450(-) (comYC) [Streptococcus sanguinis strain NCTC 10904]
MKKLNTLKVQAFTLVEMLIVLLVISVLLLLFVPNLTKQKDAVSDTGTAAVVKVVESQAELYELKNTNEKASLSKLVSAGN
ISQKQADSYKAYYGKHSGETQAVAN

Nucleotide

• Length: 318 bp

>NTDB_id=1117843 ELZ47_RS10780 WP_002896769.1 2169133..2169450(-) (comYC) [Streptococcus sanguinis strain NCTC 10904]
ATGAAAAAACTTAATACCTTAAAAGTTCAAGCATTCACCCTTGTGGAAATGCTGATTGTCTTGCTGGTTATCAGCGTTCT
CTTGCTGCTCTTTGTGCCTAATCTGACCAAGCAAAAAGATGCTGTTTCAGATACAGGAACTGCAGCGGTGGTCAAGGTGG
TAGAAAGCCAGGCGGAGCTCTATGAGCTGAAGAATACCAATGAAAAGGCTAGCCTAAGCAAGCTGGTCAGCGCAGGAAAT
ATCAGCCAGAAACAGGCAGATTCTTATAAGGCTTACTATGGAAAACACAGTGGCGAAACTCAAGCGGTTGCCAATTAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (9-30)

3D structure

• AlphaFold DB: F3SKF6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYC	Streptococcus gordonii str. Challis substr. CH1	82.857	100	0.829
comYC	Streptococcus mutans UA159	68.571	100	0.686
comYC	Streptococcus mutans UA140	68.571	100	0.686
comGC/cglC	Streptococcus mitis NCTC 12261	65.138	100	0.676
comGC/cglC	Streptococcus mitis SK321	65.421	100	0.667
comGC/cglC	Streptococcus pneumoniae Rx1	63.551	100	0.648
comGC/cglC	Streptococcus pneumoniae D39	63.551	100	0.648
comGC/cglC	Streptococcus pneumoniae TIGR4	63.551	100	0.648
comGC/cglC	Streptococcus pneumoniae R6	63.551	100	0.648
comGC	Lactococcus lactis subsp. cremoris KW2	59	95.238	0.562
comYC	Streptococcus suis isolate S10	61.798	84.762	0.524
comGC	Staphylococcus aureus MW2	43.878	93.333	0.41
comGC	Staphylococcus aureus N315	43.878	93.333	0.41