Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   ELZ47_RS10770 Genome accession   NZ_LR134002
Coordinates   2168480..2168773 (-) Length   97 a.a.
NCBI ID   WP_126436003.1    Uniprot ID   -
Organism   Streptococcus sanguinis strain NCTC 10904     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2163480..2173773
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ELZ47_RS10740 (NCTC10904_02111) - 2163760..2164398 (-) 639 WP_126435997.1 CAAX protease family protein -
  ELZ47_RS10745 (NCTC10904_02112) - 2164516..2165265 (-) 750 WP_164549614.1 CPBP family intramembrane glutamic endopeptidase -
  ELZ47_RS10750 (NCTC10904_02113) - 2165409..2166602 (-) 1194 WP_126435999.1 acetate kinase -
  ELZ47_RS10755 (NCTC10904_02114) comYH 2166639..2167604 (-) 966 WP_126436000.1 class I SAM-dependent methyltransferase Machinery gene
  ELZ47_RS10760 (NCTC10904_02115) comGG 2167686..2168078 (-) 393 WP_126436001.1 competence type IV pilus minor pilin ComGG -
  ELZ47_RS10765 (NCTC10904_02116) comGF/cglF 2168059..2168496 (-) 438 WP_126436002.1 competence type IV pilus minor pilin ComGF Machinery gene
  ELZ47_RS10770 (NCTC10904_02117) comGE/cglE 2168480..2168773 (-) 294 WP_126436003.1 competence type IV pilus minor pilin ComGE Machinery gene
  ELZ47_RS10775 (NCTC10904_02118) comYD 2168739..2169173 (-) 435 WP_164549615.1 competence type IV pilus minor pilin ComGD Machinery gene
  ELZ47_RS10780 (NCTC10904_02119) comYC 2169133..2169450 (-) 318 WP_002896769.1 competence type IV pilus major pilin ComGC Machinery gene
  ELZ47_RS10785 (NCTC10904_02120) comYB 2169450..2170484 (-) 1035 WP_269460457.1 competence type IV pilus assembly protein ComGB Machinery gene
  ELZ47_RS10790 (NCTC10904_02121) comYA 2170414..2171355 (-) 942 WP_126436006.1 competence type IV pilus ATPase ComGA Machinery gene
  ELZ47_RS10795 (NCTC10904_02122) - 2171485..2171865 (-) 381 WP_126436007.1 DUF1033 family protein -
  ELZ47_RS10800 (NCTC10904_02123) - 2172004..2173065 (-) 1062 WP_126436008.1 zinc-dependent alcohol dehydrogenase family protein -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10953.99 Da        Isoelectric Point: 10.9361

>NTDB_id=1117841 ELZ47_RS10770 WP_126436003.1 2168480..2168773(-) (comGE/cglE) [Streptococcus sanguinis strain NCTC 10904]
MASLKRRQLQASILLEALVAMAVFAAIASLLLGQISRSRKEQRVLLQQEEVLRVARMALQTGQEELHINGIAVRQLKTEK
QLLVYHEGEVVIRVQKP

Nucleotide


Download         Length: 294 bp        

>NTDB_id=1117841 ELZ47_RS10770 WP_126436003.1 2168480..2168773(-) (comGE/cglE) [Streptococcus sanguinis strain NCTC 10904]
ATGGCAAGTTTAAAAAGACGACAGCTTCAAGCTAGCATTCTGCTAGAAGCTCTGGTGGCCATGGCAGTTTTTGCGGCTAT
TGCCAGTTTGCTTTTGGGGCAGATTAGCCGGTCTCGTAAGGAGCAGCGGGTCCTTTTGCAGCAGGAAGAGGTGCTCCGGG
TAGCTCGCATGGCTCTGCAGACAGGGCAGGAAGAGCTTCATATCAACGGAATTGCTGTACGTCAGCTTAAGACAGAAAAG
CAGCTGCTGGTCTATCATGAGGGGGAGGTAGTCATTCGTGTTCAAAAACCTTAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus pneumoniae TIGR4

50.515

100

0.505
  comGE/cglE Streptococcus pneumoniae Rx1

50.515

100

0.505
  comGE/cglE Streptococcus pneumoniae D39

50.515

100

0.505
  comGE/cglE Streptococcus pneumoniae R6

50.515

100

0.505
  comGE/cglE Streptococcus mitis NCTC 12261

49.485

100

0.495
  comGE/cglE Streptococcus mitis SK321

49.485

100

0.495
  comYE Streptococcus mutans UA140

41.667

98.969

0.412
  comYE Streptococcus mutans UA159

41.667

98.969

0.412

Multiple sequence alignment