Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   ELZ47_RS10785 Genome accession   NZ_LR134002
Coordinates   2169450..2170484 (-) Length   344 a.a.
NCBI ID   WP_269460457.1    Uniprot ID   -
Organism   Streptococcus sanguinis strain NCTC 10904     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2164450..2175484
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ELZ47_RS10745 (NCTC10904_02112) - 2164516..2165265 (-) 750 WP_164549614.1 CPBP family intramembrane glutamic endopeptidase -
  ELZ47_RS10750 (NCTC10904_02113) - 2165409..2166602 (-) 1194 WP_126435999.1 acetate kinase -
  ELZ47_RS10755 (NCTC10904_02114) comYH 2166639..2167604 (-) 966 WP_126436000.1 class I SAM-dependent methyltransferase Machinery gene
  ELZ47_RS10760 (NCTC10904_02115) comGG 2167686..2168078 (-) 393 WP_126436001.1 competence type IV pilus minor pilin ComGG -
  ELZ47_RS10765 (NCTC10904_02116) comGF/cglF 2168059..2168496 (-) 438 WP_126436002.1 competence type IV pilus minor pilin ComGF Machinery gene
  ELZ47_RS10770 (NCTC10904_02117) comGE/cglE 2168480..2168773 (-) 294 WP_126436003.1 competence type IV pilus minor pilin ComGE Machinery gene
  ELZ47_RS10775 (NCTC10904_02118) comYD 2168739..2169173 (-) 435 WP_164549615.1 competence type IV pilus minor pilin ComGD Machinery gene
  ELZ47_RS10780 (NCTC10904_02119) comYC 2169133..2169450 (-) 318 WP_002896769.1 competence type IV pilus major pilin ComGC Machinery gene
  ELZ47_RS10785 (NCTC10904_02120) comYB 2169450..2170484 (-) 1035 WP_269460457.1 competence type IV pilus assembly protein ComGB Machinery gene
  ELZ47_RS10790 (NCTC10904_02121) comYA 2170414..2171355 (-) 942 WP_126436006.1 competence type IV pilus ATPase ComGA Machinery gene
  ELZ47_RS10795 (NCTC10904_02122) - 2171485..2171865 (-) 381 WP_126436007.1 DUF1033 family protein -
  ELZ47_RS10800 (NCTC10904_02123) - 2172004..2173065 (-) 1062 WP_126436008.1 zinc-dependent alcohol dehydrogenase family protein -
  ELZ47_RS10805 (NCTC10904_02124) - 2173236..2174342 (-) 1107 WP_002896776.1 glycosyl hydrolase family 8 -

Sequence

Protein


Download         Length: 344 a.a.        Molecular weight: 38946.97 Da        Isoelectric Point: 9.4984

>NTDB_id=1117844 ELZ47_RS10785 WP_269460457.1 2169450..2170484(-) (comYB) [Streptococcus sanguinis strain NCTC 10904]
MISFLQKDISVLSKGRPKKLSTPKQKKIIELFHNLFSSGFHLAEIVDFLRRSALLEEVYVAEMRAGLSAGQSFSEIVSRL
GFSDSVVTQLSLSELHGNLTLSLGKIEAYLENLSKVKKKLIEVGTYPLMLLGFLVLIMLGLRNYLLPQLDSQNLATRLIN
HLPQIFLWSSLALAVLVSVALFYYRKSSKIRFFSKLAALPFIGRLVQAYLTAYYAREWGNMIGQGLELSQIFAIMQDQPS
QLFQEIGVDMAAALQAGQGYADKVASYPFFKKELSLMIEYGEVKSKLGSELEVYAEKTWEEFFLRINRAMNFIQPLVFIF
VALVIVLLYAAMLLPIYQNMEVHL

Nucleotide


Download         Length: 1035 bp        

>NTDB_id=1117844 ELZ47_RS10785 WP_269460457.1 2169450..2170484(-) (comYB) [Streptococcus sanguinis strain NCTC 10904]
TTGATCAGCTTTTTGCAGAAGGACATATCAGTGCTGAGCAAAGGCAGACCGAAAAAATTGTCTACGCCTAAGCAGAAAAA
GATTATTGAGCTCTTTCATAATCTCTTTAGCAGCGGTTTTCACCTAGCAGAGATTGTAGACTTTCTGAGACGAAGTGCCT
TGCTGGAGGAAGTGTATGTCGCAGAAATGCGGGCAGGATTGTCAGCTGGCCAGTCCTTTTCAGAGATTGTCAGCCGACTG
GGATTTTCCGACAGCGTTGTCACCCAGCTGTCCTTATCTGAGCTGCATGGCAATTTGACTCTAAGTCTGGGGAAAATTGA
GGCCTATCTGGAAAATCTGTCCAAGGTTAAGAAAAAATTGATAGAGGTAGGGACTTATCCTCTCATGCTGCTGGGCTTTT
TGGTCCTTATCATGCTGGGATTGCGCAACTATCTTCTGCCTCAATTGGACAGCCAGAATCTAGCTACTCGTCTGATTAAT
CACCTGCCTCAGATCTTTTTGTGGAGCAGCCTTGCTTTAGCTGTCTTGGTTTCAGTGGCTCTCTTTTACTATCGAAAGTC
ATCTAAGATTCGTTTTTTCAGCAAACTAGCAGCTCTGCCTTTTATTGGACGTTTGGTACAGGCTTACTTGACAGCTTATT
ATGCTCGTGAATGGGGAAATATGATTGGTCAGGGCTTGGAGTTGAGTCAGATTTTTGCGATTATGCAGGATCAACCTTCC
CAACTCTTTCAGGAGATCGGAGTAGACATGGCGGCCGCTTTGCAAGCTGGACAAGGTTATGCGGACAAGGTGGCAAGCTA
TCCATTCTTTAAGAAAGAATTGTCCCTGATGATCGAGTATGGTGAGGTCAAGTCCAAGCTAGGCAGTGAGCTGGAAGTCT
ATGCAGAAAAGACTTGGGAGGAATTTTTCCTACGTATCAACCGAGCCATGAATTTCATTCAGCCCCTAGTATTTATTTTT
GTTGCCTTAGTGATTGTTTTACTTTATGCGGCAATGCTCTTGCCCATTTATCAGAATATGGAGGTTCATTTGTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(29-147)

Type II secretion system (T2SS), protein F (T2SSF)

(215-335)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus gordonii str. Challis substr. CH1

73.547

100

0.735
  comGB/cglB Streptococcus mitis NCTC 12261

69.94

97.674

0.683
  comGB/cglB Streptococcus mitis SK321

68.452

97.674

0.669
  comGB/cglB Streptococcus pneumoniae TIGR4

68.155

97.674

0.666
  comGB/cglB Streptococcus pneumoniae R6

68.155

97.674

0.666
  comGB/cglB Streptococcus pneumoniae Rx1

68.155

97.674

0.666
  comGB/cglB Streptococcus pneumoniae D39

68.155

97.674

0.666
  comYB Streptococcus mutans UA140

61.516

99.709

0.613
  comYB Streptococcus mutans UA159

61.516

99.709

0.613
  comGB Lactococcus lactis subsp. cremoris KW2

51.039

97.965

0.5

Multiple sequence alignment