Detailed information NTG1117840

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: ELZ47_RS10765
• Genome accession: NZ_LR134002
• Coordinates: 2168059..2168496 (-)
• Length: 145 a.a.
• NCBI ID: WP_126436002.1
• Uniprot ID: A0AAJ5NQV0
• Organism: Streptococcus sanguinis strain NCTC 10904
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2163059..2173496

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ELZ47_RS10740 (NCTC10904_02111)	-	2163760..2164398 (-)	639	WP_126435997.1	CAAX protease family protein	-
ELZ47_RS10745 (NCTC10904_02112)	-	2164516..2165265 (-)	750	WP_164549614.1	CPBP family intramembrane glutamic endopeptidase	-
ELZ47_RS10750 (NCTC10904_02113)	-	2165409..2166602 (-)	1194	WP_126435999.1	acetate kinase	-
ELZ47_RS10755 (NCTC10904_02114)	comYH	2166639..2167604 (-)	966	WP_126436000.1	class I SAM-dependent methyltransferase	Machinery gene
ELZ47_RS10760 (NCTC10904_02115)	comGG	2167686..2168078 (-)	393	WP_126436001.1	competence type IV pilus minor pilin ComGG	-
ELZ47_RS10765 (NCTC10904_02116)	comGF/cglF	2168059..2168496 (-)	438	WP_126436002.1	competence type IV pilus minor pilin ComGF	Machinery gene
ELZ47_RS10770 (NCTC10904_02117)	comGE/cglE	2168480..2168773 (-)	294	WP_126436003.1	competence type IV pilus minor pilin ComGE	Machinery gene
ELZ47_RS10775 (NCTC10904_02118)	comYD	2168739..2169173 (-)	435	WP_164549615.1	competence type IV pilus minor pilin ComGD	Machinery gene
ELZ47_RS10780 (NCTC10904_02119)	comYC	2169133..2169450 (-)	318	WP_002896769.1	competence type IV pilus major pilin ComGC	Machinery gene
ELZ47_RS10785 (NCTC10904_02120)	comYB	2169450..2170484 (-)	1035	WP_269460457.1	competence type IV pilus assembly protein ComGB	Machinery gene
ELZ47_RS10790 (NCTC10904_02121)	comYA	2170414..2171355 (-)	942	WP_126436006.1	competence type IV pilus ATPase ComGA	Machinery gene
ELZ47_RS10795 (NCTC10904_02122)	-	2171485..2171865 (-)	381	WP_126436007.1	DUF1033 family protein	-
ELZ47_RS10800 (NCTC10904_02123)	-	2172004..2173065 (-)	1062	WP_126436008.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 145 a.a.
• Molecular weight: 16885.29 Da
• Isoelectric Point: 6.1084

>NTDB_id=1117840 ELZ47_RS10765 WP_126436002.1 2168059..2168496(-) (comGF/cglF) [Streptococcus sanguinis strain NCTC 10904]
MFKNLKVKAFTLLEALVALLVLSGGMLVFQAMTQLLSSELHQQENNQQQEWLLFADQLETELSRSQFDKVEDNKIYIRQD
GRDLALGKSKGDDFRKTDKSGRGYQPMIYGLEAADIHQKGKLIHMHFRFEKGLEREFIYRVEEES

Nucleotide

• Length: 438 bp

>NTDB_id=1117840 ELZ47_RS10765 WP_126436002.1 2168059..2168496(-) (comGF/cglF) [Streptococcus sanguinis strain NCTC 10904]
GTGTTCAAAAACCTTAAAGTCAAGGCCTTTACTCTCTTGGAGGCCTTAGTAGCCTTGCTGGTTCTCAGTGGTGGCATGCT
GGTCTTTCAGGCCATGACCCAGCTCTTATCTTCAGAACTGCATCAGCAGGAGAATAATCAGCAGCAAGAGTGGCTTTTGT
TTGCCGACCAACTGGAGACGGAGCTTTCGCGAAGTCAATTTGATAAGGTTGAAGATAACAAAATCTACATCAGACAGGAT
GGCAGGGACCTGGCCTTGGGTAAATCCAAGGGGGATGATTTCCGTAAAACAGATAAGAGCGGTCGCGGCTACCAGCCGAT
GATTTATGGTTTGGAAGCAGCTGATATCCATCAGAAAGGTAAGCTTATTCATATGCATTTTCGCTTTGAAAAAGGCTTAG
AGAGGGAGTTCATCTATCGTGTGGAAGAAGAAAGTTGA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (37-134)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	64.789	97.931	0.634
comGF/cglF	Streptococcus pneumoniae D39	64.789	97.931	0.634
comGF/cglF	Streptococcus pneumoniae R6	64.789	97.931	0.634
comGF/cglF	Streptococcus pneumoniae TIGR4	64.789	97.931	0.634
comGF/cglF	Streptococcus mitis SK321	63.83	97.241	0.621
comGF/cglF	Streptococcus mitis NCTC 12261	63.121	97.241	0.614
comYF	Streptococcus mutans UA159	46.429	96.552	0.448
comYF	Streptococcus mutans UA140	45.714	96.552	0.441
comGF	Lactococcus lactis subsp. cremoris KW2	43.382	93.793	0.407