Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   ELZ47_RS10790 Genome accession   NZ_LR134002
Coordinates   2170414..2171355 (-) Length   313 a.a.
NCBI ID   WP_126436006.1    Uniprot ID   -
Organism   Streptococcus sanguinis strain NCTC 10904     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2165414..2176355
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ELZ47_RS10755 (NCTC10904_02114) comYH 2166639..2167604 (-) 966 WP_126436000.1 class I SAM-dependent methyltransferase Machinery gene
  ELZ47_RS10760 (NCTC10904_02115) comGG 2167686..2168078 (-) 393 WP_126436001.1 competence type IV pilus minor pilin ComGG -
  ELZ47_RS10765 (NCTC10904_02116) comGF/cglF 2168059..2168496 (-) 438 WP_126436002.1 competence type IV pilus minor pilin ComGF Machinery gene
  ELZ47_RS10770 (NCTC10904_02117) comGE/cglE 2168480..2168773 (-) 294 WP_126436003.1 competence type IV pilus minor pilin ComGE Machinery gene
  ELZ47_RS10775 (NCTC10904_02118) comYD 2168739..2169173 (-) 435 WP_164549615.1 competence type IV pilus minor pilin ComGD Machinery gene
  ELZ47_RS10780 (NCTC10904_02119) comYC 2169133..2169450 (-) 318 WP_002896769.1 competence type IV pilus major pilin ComGC Machinery gene
  ELZ47_RS10785 (NCTC10904_02120) comYB 2169450..2170484 (-) 1035 WP_269460457.1 competence type IV pilus assembly protein ComGB Machinery gene
  ELZ47_RS10790 (NCTC10904_02121) comYA 2170414..2171355 (-) 942 WP_126436006.1 competence type IV pilus ATPase ComGA Machinery gene
  ELZ47_RS10795 (NCTC10904_02122) - 2171485..2171865 (-) 381 WP_126436007.1 DUF1033 family protein -
  ELZ47_RS10800 (NCTC10904_02123) - 2172004..2173065 (-) 1062 WP_126436008.1 zinc-dependent alcohol dehydrogenase family protein -
  ELZ47_RS10805 (NCTC10904_02124) - 2173236..2174342 (-) 1107 WP_002896776.1 glycosyl hydrolase family 8 -
  ELZ47_RS10810 (NCTC10904_02125) - 2174351..2175661 (-) 1311 WP_002901729.1 glycosyltransferase family 2 protein -
  ELZ47_RS10815 (NCTC10904_02126) - 2175654..2175797 (-) 144 WP_002896778.1 hypothetical protein -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35895.19 Da        Isoelectric Point: 5.9407

>NTDB_id=1117845 ELZ47_RS10790 WP_126436006.1 2170414..2171355(-) (comYA) [Streptococcus sanguinis strain NCTC 10904]
MVQEIAKEMIRQARQEGAQDIYLIPKTTCYELYMRIGDERRFIKTYDFELLSAVISHFKFVAGMNVGEKRRSQLGSCDYD
CEEAKVSIRLSTVGDYRGFESLVIRLLHDEDRELRFWFEQLPELRKKIQARGLYLFSGPVGSGKTTLMYHLAQLKFSGQQ
VMSIEDPVEIKQEAMLQLQLNETIGMTYDILIKLSLRHRPDLLIIGEIRDQETARAVVRASLTGATVFSTIHAKSVRGVY
ERLLELGVSEDELRMVLQGVCYQRLIGGGGVVDFVSQNYQEHEAAVWNQQIDQLFAEGHISAEQRQTEKIVYA

Nucleotide


Download         Length: 942 bp        

>NTDB_id=1117845 ELZ47_RS10790 WP_126436006.1 2170414..2171355(-) (comYA) [Streptococcus sanguinis strain NCTC 10904]
ATGGTTCAAGAAATTGCAAAAGAAATGATCAGGCAGGCTCGGCAAGAAGGGGCGCAAGATATTTACCTCATTCCTAAGAC
TACTTGCTATGAGCTTTATATGAGAATTGGTGATGAACGCCGCTTTATAAAGACTTATGATTTTGAACTTCTGTCAGCTG
TTATCAGCCACTTTAAGTTTGTCGCAGGTATGAATGTTGGAGAGAAGCGCCGAAGTCAGCTGGGGTCTTGCGATTATGAC
TGTGAGGAAGCCAAGGTTTCAATCCGGCTGTCGACAGTTGGGGATTACCGTGGTTTTGAAAGTCTGGTCATCCGACTTCT
GCATGATGAAGACAGGGAGCTGCGCTTTTGGTTTGAGCAATTGCCGGAGCTGCGCAAGAAAATTCAGGCTCGCGGTCTCT
ATCTTTTCTCGGGTCCAGTCGGCAGCGGCAAGACGACCTTGATGTACCATTTGGCTCAGCTTAAATTTTCTGGTCAGCAG
GTTATGTCGATTGAAGATCCGGTTGAGATTAAGCAAGAGGCTATGCTGCAGCTGCAGCTGAACGAAACCATTGGCATGAC
TTATGATATTCTGATTAAGCTGTCTCTGCGACATCGACCGGATCTCTTGATTATCGGGGAAATCCGTGATCAAGAGACGG
CTAGAGCAGTGGTTCGGGCAAGTTTGACTGGAGCTACAGTCTTTTCGACCATTCATGCTAAGAGTGTTCGAGGGGTCTAT
GAGCGGCTTTTGGAATTGGGTGTTAGCGAGGATGAGCTAAGAATGGTGTTGCAAGGTGTTTGTTACCAGCGTTTAATTGG
GGGAGGGGGTGTCGTTGATTTTGTCAGTCAAAACTATCAAGAGCACGAAGCCGCAGTCTGGAATCAGCAGATTGATCAGC
TTTTTGCAGAAGGACATATCAGTGCTGAGCAAAGGCAGACCGAAAAAATTGTCTACGCCTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

80.323

99.042

0.796
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

75.08

100

0.751
  comGA/cglA/cilD Streptococcus pneumoniae D39

75.08

100

0.751
  comGA/cglA/cilD Streptococcus pneumoniae R6

75.08

100

0.751
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

75.08

100

0.751
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

74.76

100

0.748
  comYA Streptococcus mutans UA159

65.916

99.361

0.655
  comYA Streptococcus mutans UA140

65.916

99.361

0.655
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

64.516

99.042

0.639
  comGA Lactococcus lactis subsp. cremoris KW2

55.449

99.681

0.553
  comGA Latilactobacillus sakei subsp. sakei 23K

41.007

88.818

0.364

Multiple sequence alignment