Detailed information NTG1111405

Bioinformatically predicted

Overview

• Name: comX/comX2
• Type: Regulator
• Locus tag: ACN076_RS00075
• Genome accession: NZ_CP184836
• Coordinates: 6082..6561 (-)
• Length: 159 a.a.
• NCBI ID: WP_203176455.1
• Uniprot ID: -
• Organism: Streptococcus sp. K0074
• Function: activate transcription of late competence genes (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IScluster/Tn	6785..13669	6082..6561	flank	224

Gene organization within MGE regions

Location: 6082..13669

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACN076_RS00075 (ACN076_00075)	comX/comX2	6082..6561 (-)	480	WP_203176455.1	sigma-70 family RNA polymerase sigma factor	Regulator
ACN076_RS00080 (ACN076_00080)	-	6785..8041 (+)	1257	WP_420789534.1	ISL3 family transposase	-
ACN076_RS00085 (ACN076_00085)	nusG	8105..8641 (-)	537	WP_000376740.1	transcription termination/antitermination protein NusG	-
ACN076_RS00090 (ACN076_00090)	secE	8696..8872 (-)	177	WP_001210991.1	preprotein translocase subunit SecE	-
ACN076_RS00095 (ACN076_00095)	rpmG	8882..9034 (-)	153	WP_014017356.1	50S ribosomal protein L33	-
ACN076_RS00100 (ACN076_00100)	pbp2a	9087..11282 (-)	2196	WP_153193857.1	penicillin-binding protein PBP2A	-
ACN076_RS00105 (ACN076_00105)	-	11369..12244 (+)	876	WP_314725883.1	RluA family pseudouridine synthase	-

Sequence

Protein

• Length: 159 a.a.
• Molecular weight: 20020.80 Da
• Isoelectric Point: 8.4062

>NTDB_id=1111405 ACN076_RS00075 WP_203176455.1 6082..6561(-) (comX/comX2) [Streptococcus sp. K0074]
MLKKMYEEVQGIVYKCRNEYYLHLWELSDWDQEGMICLHELISREEGLVEDIPRLRKYFKTKFRNRVLDYIRKQESQKRR
YDKELYEEVGEISHRISEGGLWLDDYYLFHETLRDYRNKQTKEQQEELERVLRNERFRGRQRVLRDLRIVFKEFDLRSR

Nucleotide

• Length: 480 bp

>NTDB_id=1111405 ACN076_RS00075 WP_203176455.1 6082..6561(-) (comX/comX2) [Streptococcus sp. K0074]
ATGCTTAAAAAAATGTATGAAGAAGTGCAGGGGATTGTATATAAGTGTAGAAATGAATATTACCTTCATTTATGGGAGTT
ATCGGATTGGGACCAAGAGGGAATGATATGCCTACATGAATTGATCAGTAGAGAAGAGGGTCTAGTAGAAGATATCCCTC
GTTTAAGGAAATATTTCAAAACCAAGTTTCGAAATCGGGTTCTAGACTATATCCGTAAACAAGAAAGTCAAAAACGAAGA
TATGATAAAGAGCTTTATGAAGAAGTGGGTGAGATTAGTCATCGTATAAGTGAGGGAGGACTCTGGCTAGATGACTATTA
TCTCTTTCATGAGACACTAAGAGATTATAGAAACAAACAAACTAAAGAACAACAAGAAGAGTTAGAACGCGTCTTAAGAA
ATGAACGTTTCCGAGGGCGTCAAAGAGTCCTAAGAGACTTACGTATTGTGTTTAAAGAGTTTGATCTCCGTAGCCGGTAA

Domains

No domain identified.

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comX/comX1	Streptococcus pneumoniae Rx1	91.139	99.371	0.906
comX/comX2	Streptococcus pneumoniae D39	91.139	99.371	0.906
comX/comX1	Streptococcus pneumoniae D39	91.139	99.371	0.906
comX/comX2	Streptococcus pneumoniae R6	91.139	99.371	0.906
comX/comX1	Streptococcus pneumoniae R6	91.139	99.371	0.906
comX/comX2	Streptococcus pneumoniae Rx1	91.139	99.371	0.906
comX/sigX/comX1/sigX1	Streptococcus mitis NCTC 12261	90.506	99.371	0.899
comX/comX2	Streptococcus pneumoniae TIGR4	90.506	99.371	0.899
comX/comX1	Streptococcus pneumoniae TIGR4	90.506	99.371	0.899
comX/sigX/comX2/sigX2	Streptococcus mitis NCTC 12261	90.506	99.371	0.899
comX/sigX/comX2/sigX2	Streptococcus mitis SK321	89.873	99.371	0.893
comX/sigX/comX1/sigX1	Streptococcus mitis SK321	88.05	100	0.881
comR/comR2	Streptococcus gordonii str. Challis substr. CH1	48.366	96.226	0.465
comR/comR1	Streptococcus gordonii str. Challis substr. CH1	48.366	96.226	0.465
comX/sigX	Streptococcus mutans UA159	44.667	94.34	0.421
comX/sigX	Streptococcus suis D9	43.791	96.226	0.421
comX/sigX	Streptococcus suis isolate S10	43.791	96.226	0.421
comX/sigX	Streptococcus suis P1/7	43.791	96.226	0.421
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS315	42.105	95.597	0.403
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS315	42.105	95.597	0.403
comX/sigX/comX2/sigX2	Streptococcus pyogenes JRS4	42.105	95.597	0.403
comX/sigX/comX1/sigX1	Streptococcus pyogenes JRS4	42.105	95.597	0.403
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS8232	42.105	95.597	0.403
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS8232	42.105	95.597	0.403
comX	Streptococcus thermophilus LMG 18311	38.816	95.597	0.371
comX	Streptococcus thermophilus LMD-9	38.816	95.597	0.371
comX	Streptococcus sobrinus strain NIDR 6715-7	39.333	94.34	0.371
comX	Streptococcus salivarius SK126	38.667	94.34	0.365