Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/comX2   Type   Regulator
Locus tag   ACAM22_RS08690 Genome accession   NZ_AP028929
Coordinates   1877424..1877903 (-) Length   159 a.a.
NCBI ID   WP_261053121.1    Uniprot ID   A0AAT9G2Y1
Organism   Streptococcus sp. SN-1     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 1864008..1877903 1877424..1877903 within 0
IS/Tn 1875973..1877139 1877424..1877903 flank 285


Gene organization within MGE regions


Location: 1864008..1877903
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACAM22_RS08580 (MASAN616_16700) - 1864008..1865174 (+) 1167 WP_369606686.1 IS30 family transposase -
  ACAM22_RS08585 (MASAN616_16710) - 1865593..1866192 (-) 600 WP_261054128.1 response regulator transcription factor -
  ACAM22_RS08590 (MASAN616_16720) - 1866193..1867290 (-) 1098 WP_261054130.1 sensor histidine kinase -
  ACAM22_RS08595 (MASAN616_16730) - 1867290..1868027 (-) 738 WP_261054132.1 ABC transporter permease -
  ACAM22_RS08600 (MASAN616_16740) - 1868029..1868913 (-) 885 WP_265472273.1 ABC transporter ATP-binding protein -
  ACAM22_RS08605 (MASAN616_16750) - 1868900..1869094 (-) 195 WP_219967532.1 hypothetical protein -
  ACAM22_RS08610 (MASAN616_16760) - 1869091..1869282 (-) 192 WP_000681201.1 hypothetical protein -
  ACAM22_RS08685 (MASAN616_16780) - 1875973..1877139 (+) 1167 WP_369606687.1 IS30 family transposase -
  ACAM22_RS08690 (MASAN616_16790) comX/comX2 1877424..1877903 (-) 480 WP_261053121.1 sigma-70 family RNA polymerase sigma factor Regulator

Sequence

Protein


Download         Length: 159 a.a.        Molecular weight: 19984.81 Da        Isoelectric Point: 8.8310

>NTDB_id=107354 ACAM22_RS08690 WP_261053121.1 1877424..1877903(-) (comX/comX2) [Streptococcus sp. SN-1]
MLKKMYEEVQGIVYKCRNEYYLHLWELSDWDQEGMICLHELISKEEGLVEDIPRLRKYFKTKFRNRILDYLRKQESQKRR
YDKELYEEVGEISHRISEGGLWLDDYYLFHETLRDYRNKQNKEQRAELERVLRNERFRGRQRVLRDLRIVFKEFDIRTH

Nucleotide


Download         Length: 480 bp        

>NTDB_id=107354 ACAM22_RS08690 WP_261053121.1 1877424..1877903(-) (comX/comX2) [Streptococcus sp. SN-1]
ATGCTTAAAAAAATGTATGAAGAAGTCCAAGGAATTGTATACAAGTGTAGAAATGAATATTACCTTCATTTGTGGGAGTT
ATCGGACTGGGATCAAGAGGGAATGATATGTCTACATGAATTGATTAGTAAAGAAGAAGGATTAGTAGAAGATATCCCTC
GTTTAAGGAAATATTTCAAAACAAAATTCCGGAATCGAATTCTAGATTATCTCCGTAAACAAGAAAGTCAAAAACGGAGA
TATGATAAAGAGCTTTATGAAGAAGTGGGTGAGATAAGTCATCGTATAAGTGAGGGAGGCCTGTGGCTAGACGATTATTA
TCTCTTTCATGAAACACTAAGAGATTATAGAAACAAACAAAATAAAGAGCAACGAGCAGAGTTAGAACGCGTCTTAAGAA
ATGAACGTTTCCGAGGGCGTCAAAGAGTGTTAAGAGACTTACGTATTGTGTTTAAAGAGTTTGATATCCGTACTCATTAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/comX2 Streptococcus pneumoniae R6

90.566

100

0.906
  comX/comX1 Streptococcus pneumoniae R6

90.566

100

0.906
  comX/comX2 Streptococcus pneumoniae Rx1

90.566

100

0.906
  comX/comX1 Streptococcus pneumoniae Rx1

90.566

100

0.906
  comX/comX2 Streptococcus pneumoniae D39

90.566

100

0.906
  comX/comX1 Streptococcus pneumoniae D39

90.566

100

0.906
  comX/sigX/comX1/sigX1 Streptococcus mitis NCTC 12261

89.937

100

0.899
  comX/comX2 Streptococcus pneumoniae TIGR4

89.937

100

0.899
  comX/comX1 Streptococcus pneumoniae TIGR4

89.937

100

0.899
  comX/sigX/comX2/sigX2 Streptococcus mitis NCTC 12261

89.937

100

0.899
  comX/sigX/comX2/sigX2 Streptococcus mitis SK321

88.679

100

0.887
  comX/sigX/comX1/sigX1 Streptococcus mitis SK321

88.608

99.371

0.881
  comR/comR2 Streptococcus gordonii str. Challis substr. CH1

48.366

96.226

0.465
  comR/comR1 Streptococcus gordonii str. Challis substr. CH1

48.366

96.226

0.465
  comX/sigX Streptococcus mutans UA159

44.667

94.34

0.421
  comX/sigX Streptococcus suis D9

43.791

96.226

0.421
  comX/sigX Streptococcus suis isolate S10

43.791

96.226

0.421
  comX/sigX Streptococcus suis P1/7

43.791

96.226

0.421
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

43.421

95.597

0.415
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

43.421

95.597

0.415
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

43.421

95.597

0.415
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

43.421

95.597

0.415
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

43.421

95.597

0.415
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

43.421

95.597

0.415
  comX Streptococcus thermophilus LMG 18311

39.474

95.597

0.377
  comX Streptococcus thermophilus LMD-9

39.474

95.597

0.377
  comX Streptococcus salivarius SK126

39.333

94.34

0.371
  comX/sigX Streptococcus salivarius strain HSISS4

38.667

94.34

0.365

Multiple sequence alignment