Detailed information    

insolico Bioinformatically predicted

Overview


Name   comGC/cglC   Type   Machinery gene
Locus tag   AABA19_RS09840 Genome accession   NZ_AP028609
Coordinates   1909928..1910254 (-) Length   108 a.a.
NCBI ID   WP_061630249.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain Sep4     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 1904928..1915254
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AABA19_RS09795 (TKY121806_19100) rnpA 1904945..1905316 (-) 372 WP_000739246.1 ribonuclease P protein component -
  AABA19_RS09800 - 1905333..1905464 (-) 132 WP_000768904.1 hypothetical protein -
  AABA19_RS09805 (TKY121806_19110) - 1905465..1906655 (-) 1191 WP_000167766.1 acetate kinase -
  AABA19_RS09810 (TKY121806_19120) comYH 1906706..1907659 (-) 954 WP_338170756.1 class I SAM-dependent methyltransferase Machinery gene
  AABA19_RS09815 - 1907720..1908314 (-) 595 Protein_1910 class I SAM-dependent methyltransferase -
  AABA19_RS09820 (TKY121806_19150) comGG/cglG 1908451..1908864 (-) 414 WP_050114148.1 competence type IV pilus minor pilin ComGG Machinery gene
  AABA19_RS09825 (TKY121806_19160) comGF/cglF 1908842..1909303 (-) 462 WP_063643062.1 competence type IV pilus minor pilin ComGF Machinery gene
  AABA19_RS09830 (TKY121806_19170) comGE/cglE 1909266..1909568 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  AABA19_RS09835 (TKY121806_19180) comGD/cglD 1909531..1909935 (-) 405 WP_000588023.1 competence type IV pilus minor pilin ComGD Machinery gene
  AABA19_RS09840 (TKY121806_19190) comGC/cglC 1909928..1910254 (-) 327 WP_061630249.1 comG operon protein ComGC Machinery gene
  AABA19_RS09845 (TKY121806_19200) comGB/cglB 1910256..1911272 (-) 1017 WP_075270915.1 competence type IV pilus assembly protein ComGB Machinery gene
  AABA19_RS09850 (TKY121806_19210) comGA/cglA/cilD 1911220..1912161 (-) 942 WP_016398028.1 competence type IV pilus ATPase ComGA Machinery gene
  AABA19_RS09855 (TKY121806_19220) - 1912237..1912602 (-) 366 WP_000286415.1 DUF1033 family protein -
  AABA19_RS09860 (TKY121806_19230) - 1912753..1913811 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -
  AABA19_RS09865 (TKY121806_19240) nagA 1913974..1915125 (-) 1152 WP_001134457.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence


Protein


Download         Length: 108 a.a.        Molecular weight: 12226.41 Da        Isoelectric Point: 10.1432

>NTDB_id=106468 AABA19_RS09840 WP_061630249.1 1909928..1910254(-) (comGC/cglC) [Streptococcus pneumoniae strain Sep4]
MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLEKNEDASLRKLQA
DGRITEEQVKAYNEYYTKNGGANRKVND

Nucleotide


Download         Length: 327 bp        

>NTDB_id=106468 AABA19_RS09840 WP_061630249.1 1909928..1910254(-) (comGC/cglC) [Streptococcus pneumoniae strain Sep4]
ATGAAAAAAATGATGACATTCTTGAAAAAAGCTAAGGTTAAAGCTTTTACATTGGTGGAAATGTTGGTGGTCTTGCTGAT
TATCAGCGTGCTTTTCTTGCTCTTTGTACCTAATCTGACCAAGCAAAAAGAAGCAGTCAATGACAAAGGAAAAGCAGCTG
TTGTTAAGGTGGTGGAAAGCCAGGCAGAACTTTATAGCTTAGAAAAGAATGAAGATGCTAGCCTAAGAAAGTTACAAGCA
GATGGGCGCATCACGGAAGAACAGGTTAAAGCTTATAATGAATACTATACTAAAAATGGAGGGGCAAATCGTAAAGTCAA
TGATTAA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus pneumoniae Rx1

96.296

100

0.963

  comGC/cglC Streptococcus pneumoniae D39

96.296

100

0.963

  comGC/cglC Streptococcus pneumoniae R6

96.296

100

0.963

  comGC/cglC Streptococcus pneumoniae TIGR4

96.296

100

0.963

  comGC/cglC Streptococcus mitis SK321

95.37

100

0.954

  comGC/cglC Streptococcus mitis NCTC 12261

92.857

90.741

0.843

  comYC Streptococcus gordonii str. Challis substr. CH1

66.99

95.37

0.639

  comYC Streptococcus mutans UA140

61.765

94.444

0.583

  comYC Streptococcus mutans UA159

61.765

94.444

0.583

  comYC Streptococcus suis isolate S10

69.136

75

0.519

  comGC Lactococcus lactis subsp. cremoris KW2

54.902

94.444

0.519

  comGC Staphylococcus aureus MW2

50

79.63

0.398

  comGC Staphylococcus aureus N315

50

79.63

0.398


Multiple sequence alignment