Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB/cglB   Type   Machinery gene
Locus tag   AABA19_RS09845 Genome accession   NZ_AP028609
Coordinates   1910256..1911272 (-) Length   338 a.a.
NCBI ID   WP_075270915.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain Sep4     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1905256..1916272
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AABA19_RS09800 - 1905333..1905464 (-) 132 WP_000768904.1 hypothetical protein -
  AABA19_RS09805 (TKY121806_19110) - 1905465..1906655 (-) 1191 WP_000167766.1 acetate kinase -
  AABA19_RS09810 (TKY121806_19120) comYH 1906706..1907659 (-) 954 WP_338170756.1 class I SAM-dependent methyltransferase Machinery gene
  AABA19_RS09815 - 1907720..1908314 (-) 595 Protein_1910 class I SAM-dependent methyltransferase -
  AABA19_RS09820 (TKY121806_19150) comGG/cglG 1908451..1908864 (-) 414 WP_050114148.1 competence type IV pilus minor pilin ComGG Machinery gene
  AABA19_RS09825 (TKY121806_19160) comGF/cglF 1908842..1909303 (-) 462 WP_063643062.1 competence type IV pilus minor pilin ComGF Machinery gene
  AABA19_RS09830 (TKY121806_19170) comGE/cglE 1909266..1909568 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  AABA19_RS09835 (TKY121806_19180) comGD/cglD 1909531..1909935 (-) 405 WP_000588023.1 competence type IV pilus minor pilin ComGD Machinery gene
  AABA19_RS09840 (TKY121806_19190) comGC/cglC 1909928..1910254 (-) 327 WP_061630249.1 comG operon protein ComGC Machinery gene
  AABA19_RS09845 (TKY121806_19200) comGB/cglB 1910256..1911272 (-) 1017 WP_075270915.1 competence type IV pilus assembly protein ComGB Machinery gene
  AABA19_RS09850 (TKY121806_19210) comGA/cglA/cilD 1911220..1912161 (-) 942 WP_016398028.1 competence type IV pilus ATPase ComGA Machinery gene
  AABA19_RS09855 (TKY121806_19220) - 1912237..1912602 (-) 366 WP_000286415.1 DUF1033 family protein -
  AABA19_RS09860 (TKY121806_19230) - 1912753..1913811 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -
  AABA19_RS09865 (TKY121806_19240) nagA 1913974..1915125 (-) 1152 WP_001134457.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence

Protein


Download         Length: 338 a.a.        Molecular weight: 38496.55 Da        Isoelectric Point: 9.6162

>NTDB_id=106469 AABA19_RS09845 WP_075270915.1 1910256..1911272(-) (comGB/cglB) [Streptococcus pneumoniae strain Sep4]
MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLDRSALLDKQCVTQMRAGLSQGKSFSEMMESLGCSSAI
VTQLSLAEVHGNLHLSLGKIEEYLDNLAKVKKKLIEVATYPLILLFFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQGMELTQIFQMMQEQGSQLFKEI
GQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGEVKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIV
LLYAAMLMPMYQNMEVNF

Nucleotide


Download         Length: 1017 bp        

>NTDB_id=106469 AABA19_RS09845 WP_075270915.1 1910256..1911272(-) (comGB/cglB) [Streptococcus pneumoniae strain Sep4]
ATGGACATATCACAAGTCTTCAGGCTGAGACGGAAAAAATTAGCTACAGCTAAGCAAAAAAATATCATCACCCTATTTAA
CAATCTCTTTTCTAGCGGTTTTCATCTGGTGGAGACCATCTCCTTTTTAGATAGGAGTGCTTTGTTGGACAAGCAGTGTG
TGACCCAGATGCGTGCGGGCTTGTCTCAGGGGAAATCATTCTCAGAAATGATGGAAAGTTTGGGATGTTCAAGTGCTATT
GTCACTCAGTTATCCCTAGCTGAAGTCCATGGCAATCTCCACCTGAGTTTGGGAAAGATAGAAGAGTATCTAGACAATCT
GGCCAAGGTCAAGAAAAAATTAATTGAAGTAGCGACCTATCCTTTGATTTTGCTGTTTTTTCTTCTCTTAATTATGCTGG
GGCTACGGAATTACCTGCTCCCACAACTGGATAGTAGCAATATTGCCACCCGAATTATCGGTAATCTGCCACAAATTTTT
CTAGGCATGGTAGGGCTTGTTTCCGTGCTTGCCCTTTTAGCACTAACTTTTTATAAAAGAAGTTCTAAGATGAGTGTCTT
TTCTATCTTAGCACGCCTTCCCTTTATTGGAATCTTTGTGCAGACCTACTTGACAGCCTATTATGCACGTGAATGGGGGA
ATATGATTTCACAGGGAATGGAGCTGACGCAGATTTTTCAAATGATGCAGGAACAAGGTTCCCAGCTCTTTAAAGAAATC
GGTCAAGATCTGGCTCAAACCCTGAAAAATGGCCGTGAATTTTCTCAGACGATAGGAACCTATCCTTTCTTTAGGAAGGA
ATTGAGTCTCATCATAGAGTATGGGGAAGTTAAGTCCAAGCTGGGTAGTGAGTTGGAAATCTATGCTGAAAAAACTTGGG
AAGCCTTTTTTACCCGAGTCAACCGCACCATGAATTTGGTGCAGCCACTGGTTTTTATCTTTGTGGCACTGATTATCGTT
TTACTTTATGCGGCAATGCTCATGCCCATGTATCAAAATATGGAGGTAAATTTTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(24-141)

Type II secretion system (T2SS), protein F (T2SSF)

(209-329)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB/cglB Streptococcus pneumoniae Rx1

98.817

100

0.988
  comGB/cglB Streptococcus pneumoniae D39

98.817

100

0.988
  comGB/cglB Streptococcus pneumoniae R6

98.817

100

0.988
  comGB/cglB Streptococcus pneumoniae TIGR4

98.817

100

0.988
  comGB/cglB Streptococcus mitis SK321

94.97

100

0.95
  comGB/cglB Streptococcus mitis NCTC 12261

94.675

100

0.947
  comYB Streptococcus gordonii str. Challis substr. CH1

70.833

99.408

0.704
  comYB Streptococcus mutans UA140

58.176

94.083

0.547
  comYB Streptococcus mutans UA159

58.176

94.083

0.547
  comGB Lactococcus lactis subsp. cremoris KW2

50.898

98.817

0.503

Multiple sequence alignment