Detailed information NTG0106466

Bioinformatically predicted

Overview

• Name: comGE/cglE
• Type: Machinery gene
• Locus tag: AABA19_RS09830
• Genome accession: NZ_AP028609
• Coordinates: 1909266..1909568 (-)
• Length: 100 a.a.
• NCBI ID: WP_000413382.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain Sep4
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1904266..1914568

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AABA19_RS09795 (TKY121806_19100)	rnpA	1904945..1905316 (-)	372	WP_000739246.1	ribonuclease P protein component	-
AABA19_RS09800	-	1905333..1905464 (-)	132	WP_000768904.1	hypothetical protein	-
AABA19_RS09805 (TKY121806_19110)	-	1905465..1906655 (-)	1191	WP_000167766.1	acetate kinase	-
AABA19_RS09810 (TKY121806_19120)	comYH	1906706..1907659 (-)	954	WP_338170756.1	class I SAM-dependent methyltransferase	Machinery gene
AABA19_RS09815	-	1907720..1908314 (-)	595	Protein_1910	class I SAM-dependent methyltransferase	-
AABA19_RS09820 (TKY121806_19150)	comGG/cglG	1908451..1908864 (-)	414	WP_050114148.1	competence type IV pilus minor pilin ComGG	Machinery gene
AABA19_RS09825 (TKY121806_19160)	comGF/cglF	1908842..1909303 (-)	462	WP_063643062.1	competence type IV pilus minor pilin ComGF	Machinery gene
AABA19_RS09830 (TKY121806_19170)	comGE/cglE	1909266..1909568 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
AABA19_RS09835 (TKY121806_19180)	comGD/cglD	1909531..1909935 (-)	405	WP_000588023.1	competence type IV pilus minor pilin ComGD	Machinery gene
AABA19_RS09840 (TKY121806_19190)	comGC/cglC	1909928..1910254 (-)	327	WP_061630249.1	comG operon protein ComGC	Machinery gene
AABA19_RS09845 (TKY121806_19200)	comGB/cglB	1910256..1911272 (-)	1017	WP_075270915.1	competence type IV pilus assembly protein ComGB	Machinery gene
AABA19_RS09850 (TKY121806_19210)	comGA/cglA/cilD	1911220..1912161 (-)	942	WP_016398028.1	competence type IV pilus ATPase ComGA	Machinery gene
AABA19_RS09855 (TKY121806_19220)	-	1912237..1912602 (-)	366	WP_000286415.1	DUF1033 family protein	-
AABA19_RS09860 (TKY121806_19230)	-	1912753..1913811 (-)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 100 a.a.
• Molecular weight: 11108.08 Da
• Isoelectric Point: 9.7273

>NTDB_id=106466 AABA19_RS09830 WP_000413382.1 1909266..1909568(-) (comGE/cglE) [Streptococcus pneumoniae strain Sep4]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVSINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide

• Length: 303 bp

>NTDB_id=106466 AABA19_RS09830 WP_000413382.1 1909266..1909568(-) (comGE/cglE) [Streptococcus pneumoniae strain Sep4]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCTTGCAGACAGGTCAAAATCAGGTAAGCATCAACGGAGTTGAGATTCAGGTATTTTCT
AGTGAAAAAGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

• Type II secretory pathway pseudopilin (ComGE) (16-97)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGE/cglE	Streptococcus pneumoniae Rx1	100	100	1
comGE/cglE	Streptococcus pneumoniae D39	100	100	1
comGE/cglE	Streptococcus pneumoniae R6	100	100	1
comGE/cglE	Streptococcus pneumoniae TIGR4	100	100	1
comGE/cglE	Streptococcus mitis NCTC 12261	98	100	0.98
comGE/cglE	Streptococcus mitis SK321	98	100	0.98
comYE	Streptococcus mutans UA140	44.444	90	0.4
comYE	Streptococcus mutans UA159	44.444	90	0.4