Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/blpH   Type   Regulator
Locus tag   H0514_RS10540 Genome accession   NZ_LR822020
Coordinates   355028..355831 (-) Length   267 a.a.
NCBI ID   WP_232086251.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_956     
Function   phosphorylation of ComE; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 350028..360831
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H0514_RS01860 (STHERMO_0407) comA/nlmT 351298..353451 (+) 2154 WP_133264081.1 peptide cleavage/export ABC transporter Regulator
  H0514_RS01865 (STHERMO_0408) comB 353467..354834 (+) 1368 WP_096811636.1 bacteriocin secretion accessory protein Regulator
  H0514_RS01870 (STHERMO_0409) - 354849..355010 (+) 162 WP_011226496.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  H0514_RS10540 comD/blpH 355028..355831 (-) 804 WP_232086251.1 ATP-binding protein Regulator
  H0514_RS01880 (STHERMO_0411) comE/blpR 356362..357099 (-) 738 WP_179972243.1 LytR/AlgR family response regulator transcription factor Regulator
  H0514_RS01885 (STHERMO_0412) - 357350..357526 (+) 177 WP_011681570.1 Blp family class II bacteriocin -
  H0514_RS01890 (STHERMO_0413) - 357545..357745 (+) 201 WP_011681569.1 hypothetical protein -
  H0514_RS01895 (STHERMO_0414) - 358101..358331 (+) 231 WP_011226494.1 bacteriocin class II family protein -
  H0514_RS11110 (STHERMO_0420) - 359354..359755 (+) 402 WP_011226490.1 hypothetical protein -
  H0514_RS01900 (STHERMO_0421) - 360006..360260 (+) 255 WP_179972242.1 Blp family class II bacteriocin -

Sequence

Protein


Download         Length: 267 a.a.        Molecular weight: 30821.14 Da        Isoelectric Point: 4.8260

>NTDB_id=1010018 H0514_RS10540 WP_232086251.1 355028..355831(-) (comD/blpH) [Streptococcus thermophilus isolate STH_CIRM_956]
MYLENTTHSSTLELRKLCVVISLVLFFIMIVFLDRNIREMIQGQLDFQKNLQLENLYTYNKHIECLYNSVRSFRHDYSNL
LVTLRLGIDKDDMDIVKEVYDSVLQESDKRLNTRNFDLARLVNIQDNTLKSLLSAKVLQAEEEGIEAQISIPEPIHLIGM
EILDFIIVTSIFLDNAIEGAIQTQNHKITISFWEDHRSQLLSISNTISEEQTETKTIFERGVSNKGRERGIGLANVTEIL
DNYINVNLETQSNNFSFTQQLTITKKA

Nucleotide


Download         Length: 804 bp        

>NTDB_id=1010018 H0514_RS10540 WP_232086251.1 355028..355831(-) (comD/blpH) [Streptococcus thermophilus isolate STH_CIRM_956]
ATGTATCTTGAAAACACTACTCATTCTTCAACTTTGGAGCTTCGAAAACTCTGTGTTGTTATTTCACTTGTCCTCTTCTT
CATTATGATTGTCTTTTTAGACAGAAACATTCGTGAAATGATTCAAGGACAATTGGACTTCCAAAAAAATCTCCAGCTAG
AAAATCTCTACACCTACAATAAACATATTGAATGTCTCTACAATTCTGTTCGTAGTTTTAGACACGATTATAGTAATCTC
TTAGTCACATTACGATTGGGGATAGATAAAGACGATATGGATATTGTCAAAGAAGTCTATGATAGTGTGCTTCAAGAATC
CGATAAACGATTAAATACAAGAAACTTTGACTTAGCTAGACTCGTTAATATTCAGGATAATACTTTGAAAAGCCTTCTGT
CCGCAAAAGTTTTACAAGCAGAAGAAGAAGGTATTGAAGCTCAGATTAGCATCCCAGAACCCATCCACTTGATTGGGATG
GAGATTCTGGACTTCATTATCGTCACTTCTATTTTTTTAGATAACGCTATTGAAGGTGCCATTCAAACTCAAAACCATAA
AATTACTATTAGCTTTTGGGAAGATCATCGTTCACAGCTATTATCTATTAGCAATACCATAAGTGAAGAACAAACAGAAA
CTAAAACCATATTTGAAAGAGGTGTCTCCAACAAGGGACGAGAGCGAGGCATTGGCCTTGCTAATGTCACAGAAATCTTA
GATAACTATATCAATGTAAACTTAGAAACACAGAGTAACAATTTCTCATTCACACAACAATTAACAATAACTAAAAAGGC
CTAA

Domains

Predicted by InterProScan.

GHKL domain (HATPase_c_5)

(160-263)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/blpH Streptococcus mutans UA159

38.189

95.131

0.363

Multiple sequence alignment