Detailed information of T6SS
Note: only experimentally validated proteins are displayed in the graph.
Summary
| T6SS ID | T6SS01274  |
| T6SS type | Type i2 |
| Strain | Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 |
| Replicon (RefSeq) | chromosome (NZ_CP064352) |
| Location | 1759057..1784245 |
| Function | - |
| Comment | Kp43816 possess T6SS-dependent anti-bacterial activity |
| References | [1] Storey D, McNally A, |
Experimental investigation has been performed.T6SS components and genome coordinates
| Component | TssA | TssB | TssD | TssF | TssG | TssH | TssI | TssJ | TssK | TssL | VasK |
| Number | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| Component ID | Component | Locus tag (Gene) | Coordinate | Strand | Size (bp) | NCBI ID | Product |
|---|---|---|---|---|---|---|---|
| IT767_RS08485 | 1754935..1755141 | + | 207 | WP_004176413.1 | DUF1471 domain-containing protein | ||
| IT767_RS08490 | 1755192..1756070 | - | 879 | WP_004151595.1 | AraC family transcriptional regulator | ||
| IT767_RS08495 | 1756229..1756984 | + | 756 | WP_004151596.1 | SDR family oxidoreductase | ||
| IT767_RS08500 | 1756989..1757582 | - | 594 | WP_015958263.1 | TetR/AcrR family transcriptional regulator | ||
| IT767_RS08505 (bdcA) | 1757656..1758369 | + | 714 | WP_004176415.1 | SDR family oxidoreductase | ||
| IT767_RS08510 | 1758436..1758930 | - | 495 | WP_038431758.1 | hypothetical protein | ||
| T6CP015834 | TssJ | IT767_RS08515 (tssJ) | 1759057..1759599 | - | 543 | WP_004176417.1 | type VI secretion system lipoprotein TssJ |
| T6CP015835 | TssG | IT767_RS08520 (tssG) | 1759577..1760662 | - | 1086 | WP_004212345.1 | type VI secretion system baseplate subunit TssG |
| T6CP015836 | TssF | IT767_RS08525 (tssF) | 1760626..1762380 | - | 1755 | WP_004892596.1 | type VI secretion system baseplate subunit TssF |
| T6CP015837 | TssA | IT767_RS08530 (tssA) | 1762460..1764052 | - | 1593 | WP_004183804.1 | type VI secretion system protein TssA |
| T6CP015838 | VasK | IT767_RS08535 | 1764049..1767498 | - | 3450 | WP_038431759.1 | type VI secretion protein VasK |
| T6CP015839 | TssI | IT767_RS08540 | 1767488..1768669 | - | 1182 | WP_021440008.1 | hypothetical protein |
| IT767_RS08545 | 1768618..1768875 | - | 258 | WP_023302025.1 | PAAR domain-containing protein | ||
| IT767_RS08550 | 1768918..1771317 | - | 2400 | WP_021440007.1 | DUF2235 domain-containing protein | ||
| IT767_RS08555 | 1771305..1771834 | - | 530 | pseudogene | DUF3304 domain-containing protein | ||
| IT767_RS08560 | 1771859..1772635 | - | 777 | WP_004140184.1 | DUF4123 domain-containing protein | ||
| IT767_RS08565 (vgrG) | 1772639..1775008 | - | 2370 | pseudogene | type VI secretion system tip protein VgrG | ||
| T6CP015840 | TssH | IT767_RS08570 (tssH) | 1775010..1777664 | - | 2655 | WP_038431760.1 | type VI secretion system ATPase TssH |
| T6CP015841 | TssD | IT767_RS08575 (hcp) | 1777929..1778420 | - | 492 | WP_002902160.1 | type VI secretion system effector Hcp |
| IT767_RS08580 | 1778425..1780131 | - | 1707 | WP_038431761.1 | OmpA family protein | ||
| T6CP015842 | TssL | IT767_RS08585 | 1780128..1780817 | - | 690 | WP_004176431.1 | type VI secretion system protein TssL, short form |
| T6CP015843 | TssK | IT767_RS08590 (tssK) | 1780814..1782157 | - | 1344 | WP_004224345.1 | type VI secretion system baseplate subunit TssK |
| IT767_RS08595 (tssC) | 1782167..1783711 | - | 1545 | pseudogene | type VI secretion system contractile sheath large subunit | ||
| T6CP015845 | TssB | IT767_RS08600 (tssB) | 1783754..1784245 | - | 492 | WP_004176434.1 | type VI secretion system contractile sheath small subunit |
| IT767_RS08605 | 1784886..1785452 | + | 567 | WP_038431762.1 | DJ-1/PfpI family protein | ||
| IT767_RS08610 | 1785651..1787183 | - | 1533 | WP_004224331.1 | HD domain-containing protein | ||
| IT767_RS08615 | 1787400..1788161 | - | 762 | WP_038431763.1 | SDR family oxidoreductase | ||
| IT767_RS08620 | 1788270..1789184 | + | 915 | WP_038431764.1 | LysR family transcriptional regulator |
Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files
Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
Experimental investigation has been performed.
Bioinformatics investigation has been performed.| Regulator ID | Locus tag (Gene) | Regulator type | Regulatory pathway | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Target (Regulation) |
|---|
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Effector ID | Locus tag (Gene) | Classification | Cognate immunity protein | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
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Experimental investigation has been performed. Bioinformatics investigation has been performed.| Immunity protein ID | Locus tag (Gene) | Cognate effector | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
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Experimental investigation has been performed.| Accessory protein ID | Locus tag (Gene) | Type | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Related structure protein | Related effector |
|---|