Detailed information of component protein


Summary

Component ID T6CP015840
Component protein type TssH
T6SS ID (Type) T6SS01274 experimental (Type i2)
Strain Klebsiella pneumoniae subsp. pneumoniae ATCC 43816
Replicon chromosome
Sequence Protein sequence (885 a.a.); Nucleotide sequence (2655 bp)
Reference
experimental Experimental investigation has been performed on this T6SS
External database links

Locus tag (Gene) IT767_RS08570
Coordinate (Strand) 1775010..1777664 (-)
NCBI ID WP_038431760.1
RefSeq NZ_CP064352
Uniprot ID UPI000506CE3F
KEGG ID -
PDB ID -
Pfam domain hit(s)

Domain Pfam ID E-value Aligned region
AAA_2 PF07724.16 2.9e-38 610..775
AAA_lid_9 PF17871.3 1.4e-30 378..468
ClpB_D2-small PF10431.11 1.9e-12 784..855
AAA PF00004.31 1.5e-09 238..350
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Outside 1-884 MENPASLLRRLNPCCARAMEGAASLCQTRAHAEILPEHWLLKLLEQGEGDLTVLARRYEWDMDALWQDLLSWLDKQPRSVRHRPQLSHHTLRLMQEAWLIASLSGEAQIRSVHLLMALVEKQNLIQCDGLWPLLTLGQRQLERLRPLLDAQSDERPPAQQEAALAQPHGGDVEFVGRPAGSELNADGLNPALQNALDKFTLDVTAKARDGQIDPVFGRDTEIRQMVDILSRRRKNNPILVGEPGVGKTALVEGLALRIAEGNVPDALKPVSVRTLDLGLLQAGAGVKGEFEQRLKNIIEAVQQSPSPVLLFIDEAHTIIGAGNQAGGADAANLLKPALARGELRTIAATTWSEYKQYFERDAALERRFQMVKVDEPDDDTACLMLRGLKSRYADHHGVHITDDAVRAAVTLSRRYLTGRQLPDKAVDLLDTASARLRMSLDTVPQPLTRMKAQLTALAMEKQALLEDIALGNSARGDRLAAIEQEEIRLILALDTLETQYGQELQLTEALLACRRDISRQAEISDLQTALIAVQQGNPLLGLDVDVRTVATVIADWTGVPLSSLMKDEQTELLSLEESLGKRVVGQEAALSAIARRLRAAKTGLTPENGPQGVFLLVGPSGTGKTETALALADALFGGEKALITINLSEYQEPHTVSQLKGSPPGYVGYGQGGILTEAVRKRPYSVVLLDEVEKAHRDVMNLFYQVFDRGVMRDGEGREIDFRNTVILMTANLGSDLLMQLLDEQPQASESDLHELLRPVLRGHFQPALLARFQTVIYRPLPAGALRAIVGMKLGQVSQRLACHYGITTTLSESLFDALTEACLLPDTGARNVDSLLNQQILPALSQQLLSHMAAGQKPRQVTLGYHEEEGVVMAFDEGTISDE


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.8846 - -


  Protein sequence: 885 a.a.    

>T6CP015840 NZ_CP064352:c1777664-1775010 [Klebsiella pneumoniae subsp. pneumoniae ATCC 43816] [TssH]
MENPASLLRRLNPCCARAMEGAASLCQTRAHAEILPEHWLLKLLEQGEGDLTVLARRYEWDMDALWQDLLSWLDKQPRSV
RHRPQLSHHTLRLMQEAWLIASLSGEAQIRSVHLLMALVEKQNLIQCDGLWPLLTLGQRQLERLRPLLDAQSDERPPAQQ
EAALAQPHGGDVEFVGRPAGSELNADGLNPALQNALDKFTLDVTAKARDGQIDPVFGRDTEIRQMVDILSRRRKNNPILV
GEPGVGKTALVEGLALRIAEGNVPDALKPVSVRTLDLGLLQAGAGVKGEFEQRLKNIIEAVQQSPSPVLLFIDEAHTIIG
AGNQAGGADAANLLKPALARGELRTIAATTWSEYKQYFERDAALERRFQMVKVDEPDDDTACLMLRGLKSRYADHHGVHI
TDDAVRAAVTLSRRYLTGRQLPDKAVDLLDTASARLRMSLDTVPQPLTRMKAQLTALAMEKQALLEDIALGNSARGDRLA
AIEQEEIRLILALDTLETQYGQELQLTEALLACRRDISRQAEISDLQTALIAVQQGNPLLGLDVDVRTVATVIADWTGVP
LSSLMKDEQTELLSLEESLGKRVVGQEAALSAIARRLRAAKTGLTPENGPQGVFLLVGPSGTGKTETALALADALFGGEK
ALITINLSEYQEPHTVSQLKGSPPGYVGYGQGGILTEAVRKRPYSVVLLDEVEKAHRDVMNLFYQVFDRGVMRDGEGREI
DFRNTVILMTANLGSDLLMQLLDEQPQASESDLHELLRPVLRGHFQPALLARFQTVIYRPLPAGALRAIVGMKLGQVSQR
LACHYGITTTLSESLFDALTEACLLPDTGARNVDSLLNQQILPALSQQLLSHMAAGQKPRQVTLGYHEEEGVVMAFDEGT
ISDE*

  Nucleotide sequence: 2655 bp    

>T6CP015840 NZ_CP064352:c1777664-1775010 [Klebsiella pneumoniae subsp. pneumoniae ATCC 43816] [TssH]
ATGGAAAATCCAGCCAGCCTGTTACGCCGTCTTAATCCCTGCTGTGCCCGCGCAATGGAGGGGGCGGCCTCCCTGTGCCA
GACCCGGGCGCATGCCGAGATCCTGCCCGAGCACTGGCTGCTTAAACTGCTGGAACAGGGGGAAGGCGATCTGACGGTGC
TGGCGCGGCGCTATGAATGGGATATGGATGCGCTGTGGCAGGATCTGCTGAGCTGGCTGGATAAACAGCCGCGCTCGGTA
CGTCATCGTCCCCAGCTCTCTCACCATACCCTGAGGCTGATGCAGGAGGCCTGGCTGATTGCCTCTCTCAGCGGCGAAGC
GCAGATCCGCAGTGTTCACCTGCTGATGGCGCTGGTTGAAAAACAGAATCTGATCCAGTGCGATGGCCTGTGGCCGCTGT
TAACGCTGGGCCAGCGTCAGCTGGAACGCCTGCGCCCCTTGCTGGATGCCCAGTCCGACGAACGTCCGCCAGCGCAGCAG
GAAGCGGCGCTTGCGCAGCCCCATGGCGGGGACGTGGAATTTGTGGGGCGTCCCGCGGGCAGCGAACTGAATGCGGATGG
GCTCAACCCGGCGCTGCAGAACGCGCTGGACAAATTCACTCTCGACGTCACCGCCAAAGCCAGAGACGGCCAGATTGACC
CGGTGTTCGGACGCGACACGGAAATCCGCCAGATGGTGGATATTCTCTCCCGTCGGCGAAAAAACAACCCAATCCTCGTC
GGTGAGCCGGGCGTGGGCAAGACCGCTCTGGTGGAAGGCCTGGCGCTGCGCATTGCCGAAGGCAACGTCCCCGACGCGCT
GAAGCCGGTGTCGGTGCGCACCCTTGACCTCGGTCTGCTGCAGGCCGGCGCCGGGGTCAAAGGCGAGTTCGAGCAGCGGC
TGAAAAATATCATTGAGGCGGTACAGCAGTCGCCTTCGCCGGTGCTGCTGTTTATCGACGAGGCGCACACGATCATCGGC
GCGGGTAATCAGGCGGGCGGCGCGGATGCCGCCAACCTGTTGAAGCCGGCGTTGGCCCGGGGCGAGCTGCGGACCATCGC
CGCCACCACCTGGTCTGAATACAAGCAGTACTTCGAGCGCGACGCCGCGCTGGAGCGCCGCTTTCAGATGGTCAAGGTGG
ATGAGCCGGACGACGACACCGCCTGCCTGATGCTGCGCGGCCTGAAGTCCCGCTATGCCGACCACCACGGCGTGCATATC
ACGGATGATGCGGTGCGCGCCGCCGTGACGCTGTCACGACGCTATCTCACCGGCCGCCAGCTGCCGGACAAGGCAGTGGA
TTTACTCGACACCGCTTCCGCCCGCCTGCGTATGAGTTTGGATACCGTGCCTCAGCCGCTGACCCGCATGAAGGCGCAGC
TCACCGCGCTGGCAATGGAGAAGCAGGCGCTGCTGGAAGATATTGCGCTGGGCAACAGCGCCCGCGGCGATCGGCTGGCG
GCCATTGAGCAGGAGGAGATCCGCCTTATTCTGGCGCTGGATACCCTTGAAACTCAGTATGGTCAGGAGCTGCAGCTGAC
GGAAGCGCTGCTCGCCTGTCGCCGCGATATCTCCCGCCAGGCGGAAATTAGCGATCTACAAACCGCGCTTATCGCCGTCC
AGCAGGGCAATCCGCTGCTCGGGCTGGACGTCGACGTCCGCACCGTGGCGACGGTGATTGCCGACTGGACCGGCGTGCCG
CTCTCCTCGCTAATGAAAGATGAGCAGACGGAGCTGCTGAGTCTGGAAGAGAGTCTCGGCAAACGGGTGGTTGGCCAGGA
GGCGGCCCTGAGCGCTATTGCCCGGCGCCTGCGCGCCGCGAAAACCGGCCTGACGCCGGAGAACGGTCCGCAAGGGGTGT
TCCTGCTGGTCGGGCCGAGCGGCACCGGCAAAACGGAAACGGCGCTCGCCCTCGCCGATGCGCTGTTCGGCGGCGAGAAA
GCGCTGATCACCATCAATCTCTCCGAGTACCAGGAGCCGCACACCGTTAGCCAGCTGAAGGGTTCTCCGCCCGGCTATGT
CGGCTACGGCCAGGGCGGGATCCTGACCGAGGCGGTGCGCAAACGCCCCTACAGCGTGGTGCTGCTCGATGAGGTGGAAA
AGGCCCATCGCGATGTGATGAACCTGTTCTACCAGGTCTTCGACCGGGGGGTAATGCGCGACGGCGAGGGGCGTGAAATC
GACTTTCGCAACACCGTGATCCTGATGACCGCCAACCTCGGTAGCGACCTCCTGATGCAGCTGCTGGATGAACAGCCGCA
GGCCAGCGAATCAGACCTGCACGAGCTGCTGCGCCCGGTGCTGCGCGGCCACTTCCAGCCGGCGCTGCTGGCCCGCTTCC
AGACGGTGATTTACCGTCCGCTGCCGGCGGGAGCGCTGCGCGCCATTGTCGGCATGAAGCTCGGGCAGGTAAGTCAGCGT
CTGGCTTGCCATTACGGAATCACCACCACCCTCAGCGAGAGCCTGTTCGACGCGCTGACCGAGGCCTGCCTGCTGCCGGA
TACCGGCGCCCGTAACGTCGACAGTCTGCTCAATCAGCAGATCCTGCCGGCGCTGAGTCAGCAGCTATTGAGCCATATGG
CGGCGGGGCAGAAACCGCGCCAGGTGACGCTGGGGTATCACGAAGAGGAAGGCGTCGTGATGGCGTTTGACGAGGGGACA
ATATCCGATGAGTAG