Detailed information of component protein


Summary

Component ID T6CP015836
Component protein type TssF
T6SS ID (Type) T6SS01274 experimental (Type i2)
Strain Klebsiella pneumoniae subsp. pneumoniae ATCC 43816
Replicon chromosome
Sequence Protein sequence (585 a.a.); Nucleotide sequence (1755 bp)
Reference
experimental Experimental investigation has been performed on this T6SS
External database links

Locus tag (Gene) IT767_RS08525
Coordinate (Strand) 1760626..1762380 (-)
NCBI ID WP_004892596.1
RefSeq NZ_CP064352
Uniprot ID A6T858_KLEP7, W9BFV7_KLEPN
KEGG ID kpn:KPN_01347, kpnk:BN49_2477
PDB ID -
Pfam domain hit(s)

Domain Pfam ID E-value Aligned region
T6SS_TssF PF05947.14 8.7e-179 1..581
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Outside 1-584 MDDLTLRYYDAEMRYLLEAGEEFARAHPEQAAMLNLDKAGARDPFVERLFEGFAFLMGRMREKLDDDLPELTEGVVSLLWPHYLRTIPSMSVVEFTPDWPEMKESMTIGKGFEVLSRPIGEKGTRCRYTTTKAIALQPLSLERVQLATDTDGRSVITLRFTCSQLTDWRRVDLSHIPLYCNADAPLACAMHEAFTLNVARMWLRMPDEVDRRPLDGYFSALGFGEDDGLWPEDGRSFRGYQLLLEYFTFREKFMFIDLRGLETVAFPAGLAWFEIDVVLAERWEHDFRFSEKQLRLHCVPVINLFPLESDPLTINSLQTEYPLRPMRVQDGHTEIYTVDSVISSHQQVYAPFSSFRHKGGMMRHDAADYYYHTRVRRGPSGLYNTWLIVGGEAFDNHTVPEDESLSLTLTGTNGQLPRRALQSTVLDTVMKTTSASIAVRNLCAPTLPCYPPAQDRFHWRVLSHLGSSFLSLMDNAEVLRGTLALYEWTDSEMNRRRLEAILDVKHRATERFAQGHLVRGVQIEVTLDSHGFAGRGDICLFGEMLSRFFALYTDIYLFNRLIIILQPTGERLEWEEKHSRRIPG


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.9977 - -


  Protein sequence: 585 a.a.    

>T6CP015836 NZ_CP064352:c1762380-1760626 [Klebsiella pneumoniae subsp. pneumoniae ATCC 43816] [TssF]
MDDLTLRYYDAEMRYLLEAGEEFARAHPEQAAMLNLDKAGARDPFVERLFEGFAFLMGRMREKLDDDLPELTEGVVSLLW
PHYLRTIPSMSVVEFTPDWPEMKESMTIGKGFEVLSRPIGEKGTRCRYTTTKAIALQPLSLERVQLATDTDGRSVITLRF
TCSQLTDWRRVDLSHIPLYCNADAPLACAMHEAFTLNVARMWLRMPDEVDRRPLDGYFSALGFGEDDGLWPEDGRSFRGY
QLLLEYFTFREKFMFIDLRGLETVAFPAGLAWFEIDVVLAERWEHDFRFSEKQLRLHCVPVINLFPLESDPLTINSLQTE
YPLRPMRVQDGHTEIYTVDSVISSHQQVYAPFSSFRHKGGMMRHDAADYYYHTRVRRGPSGLYNTWLIVGGEAFDNHTVP
EDESLSLTLTGTNGQLPRRALQSTVLDTVMKTTSASIAVRNLCAPTLPCYPPAQDRFHWRVLSHLGSSFLSLMDNAEVLR
GTLALYEWTDSEMNRRRLEAILDVKHRATERFAQGHLVRGVQIEVTLDSHGFAGRGDICLFGEMLSRFFALYTDIYLFNR
LIIILQPTGERLEWEEKHSRRIPG*

  Nucleotide sequence: 1755 bp    

>T6CP015836 NZ_CP064352:c1762380-1760626 [Klebsiella pneumoniae subsp. pneumoniae ATCC 43816] [TssF]
ATGGACGATTTAACCCTGCGTTATTACGACGCTGAAATGCGCTACCTGCTGGAAGCGGGTGAAGAGTTTGCCCGCGCTCA
TCCTGAGCAGGCGGCAATGCTCAATCTCGACAAAGCGGGCGCCCGCGACCCCTTTGTCGAGCGCCTGTTTGAAGGTTTTG
CCTTCCTGATGGGCCGCATGCGCGAGAAACTCGATGACGATCTGCCTGAGCTGACCGAAGGCGTGGTCAGTCTGCTGTGG
CCACATTATTTACGTACCATTCCCTCGATGTCGGTCGTGGAGTTCACCCCCGACTGGCCGGAAATGAAAGAATCGATGAC
GATAGGCAAAGGTTTTGAAGTGCTTTCCCGGCCGATCGGTGAAAAGGGCACGCGCTGCCGGTACACCACCACCAAAGCGA
TCGCTCTGCAGCCGTTATCCCTGGAACGCGTCCAGCTGGCCACCGATACGGATGGCCGGTCGGTGATCACGCTGCGCTTT
ACCTGCAGCCAGCTGACGGACTGGCGCCGGGTCGATCTCAGTCATATCCCGCTGTACTGCAACGCCGATGCGCCGCTGGC
CTGCGCCATGCACGAGGCCTTTACCCTCAATGTGGCCCGGATGTGGCTGCGCATGCCCGATGAGGTGGACAGAAGGCCGC
TGGACGGGTATTTCAGCGCGCTGGGATTTGGCGAGGATGACGGCCTCTGGCCTGAAGATGGCCGCAGTTTTCGCGGTTAC
CAGCTGCTGCTGGAGTATTTTACCTTCCGCGAAAAGTTCATGTTCATCGATCTGCGCGGGCTGGAGACGGTGGCTTTTCC
GGCCGGACTGGCGTGGTTTGAAATCGACGTCGTGCTGGCGGAACGCTGGGAACATGACTTCCGCTTCAGCGAAAAGCAGC
TGCGCCTGCACTGCGTGCCAGTGATCAACCTGTTTCCGCTGGAGTCCGATCCGCTGACCATCAATTCCCTGCAGACCGAA
TACCCGCTGCGCCCGATGCGCGTGCAGGACGGCCACACCGAAATTTACACCGTCGATTCCGTGATCTCCTCACACCAGCA
GGTTTACGCGCCGTTCTCAAGTTTTCGCCACAAAGGCGGCATGATGCGTCATGACGCGGCGGACTATTACTATCATACCC
GGGTGCGCCGTGGCCCCTCCGGGCTGTACAACACCTGGCTTATCGTCGGCGGAGAAGCCTTTGATAATCATACCGTACCG
GAAGATGAAAGCCTGTCGCTGACCCTCACCGGAACCAACGGCCAGCTGCCGCGTCGCGCGCTGCAGAGCACCGTGCTCGA
TACGGTGATGAAAACCACTTCCGCCAGTATTGCAGTGCGTAACCTCTGCGCGCCGACGCTGCCGTGCTATCCCCCCGCCC
AGGACCGTTTTCACTGGCGGGTGCTGAGCCATCTGGGCAGCAGTTTTCTTTCCCTGATGGATAACGCGGAGGTCCTGCGC
GGCACCCTGGCGCTGTATGAATGGACCGACAGCGAGATGAATCGTCGGCGTCTGGAAGCCATCCTCGACGTGAAGCACCG
CGCAACAGAGCGCTTTGCACAGGGCCATCTGGTGCGCGGCGTACAGATTGAAGTCACCCTCGACAGTCACGGCTTTGCCG
GACGAGGCGATATATGCCTGTTTGGCGAGATGCTTAGCCGCTTCTTCGCGCTCTACACCGACATCTACTTGTTCAACCGC
CTGATTATCATTCTGCAACCAACCGGAGAACGACTGGAATGGGAAGAGAAGCACAGCCGCCGCATTCCCGGCTGA