Detailed information of component protein


Summary

Component ID T6CP015839
Component protein type TssI
T6SS ID (Type) T6SS01274 experimental (Type i2)
Strain Klebsiella pneumoniae subsp. pneumoniae ATCC 43816
Replicon chromosome
Sequence Protein sequence (394 a.a.); Nucleotide sequence (1182 bp)
Reference
experimental Experimental investigation has been performed on this T6SS
External database links

Locus tag (Gene) IT767_RS08540
Coordinate (Strand) 1767488..1768669 (-)
NCBI ID WP_021440008.1
RefSeq NZ_CP064352
Uniprot ID A0A331W0E5_KLEPN, A0A377ZTV1_KLEPN
KEGG ID kpt:VK055_1094
PDB ID -
Pfam domain hit(s)

Domain Pfam ID E-value Aligned region
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Outside 1-36 MWLHAGEFQPRLQGCAVRAIPTFPRYRLAKPPVAKR
Transmembrane helix 37-56 WLGGGAALVLLSGIIAAMAG
Inside 57-62 KSDANT
Transmembrane helix 63-82 SIILICMVGMVLLGGVVWFL
Outside 83-393 RTIFFRLSVHHSHTWEREAENERRHWWEIHRRQFALKDIVLIGPAGAELSDWLRVIKREHQAPLVRQESLGKSLRIARSFSSALIEREKQLAQMLVLQWKRQRGKELFVSPEKYFWQGSPEAWQAFVAQLIESFPGITAPELPELWQGEKTLSVLANVLADKKQLANFLIAGCQSLSPASDSTRPAGECAVLWLAGNQGDVTLSRGEFFEPSDSESLRHVALRAEKQSELNESPERCILFSHPEQPELADCGWNVTHNIQDDYWGDPGKLDALVVISLAAITAKTEAKPCGWIASDPLHTLALGIVKPNGN


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.8439 - -


  Protein sequence: 394 a.a.    

>T6CP015839 NZ_CP064352:c1768669-1767488 [Klebsiella pneumoniae subsp. pneumoniae ATCC 43816] [TssI]
MWLHAGEFQPRLQGCAVRAIPTFPRYRLAKPPVAKRWLGGGAALVLLSGIIAAMAGKSDANTSIILICMVGMVLLGGVVW
FLRTIFFRLSVHHSHTWEREAENERRHWWEIHRRQFALKDIVLIGPAGAELSDWLRVIKREHQAPLVRQESLGKSLRIAR
SFSSALIEREKQLAQMLVLQWKRQRGKELFVSPEKYFWQGSPEAWQAFVAQLIESFPGITAPELPELWQGEKTLSVLANV
LADKKQLANFLIAGCQSLSPASDSTRPAGECAVLWLAGNQGDVTLSRGEFFEPSDSESLRHVALRAEKQSELNESPERCI
LFSHPEQPELADCGWNVTHNIQDDYWGDPGKLDALVVISLAAITAKTEAKPCGWIASDPLHTLALGIVKPNGN*

  Nucleotide sequence: 1182 bp    

>T6CP015839 NZ_CP064352:c1768669-1767488 [Klebsiella pneumoniae subsp. pneumoniae ATCC 43816] [TssI]
ATGTGGTTGCACGCTGGTGAGTTCCAACCCCGATTGCAGGGTTGCGCAGTGAGAGCTATTCCTACATTTCCTCGCTATCG
TCTTGCGAAACCGCCAGTTGCAAAGCGCTGGTTAGGAGGAGGTGCCGCTCTGGTTTTGCTCTCTGGTATCATCGCGGCAA
TGGCAGGGAAATCCGATGCCAATACCAGTATCATTCTTATCTGCATGGTTGGAATGGTATTACTTGGCGGTGTTGTCTGG
TTTTTACGCACAATCTTTTTTCGCCTTTCAGTTCATCATTCACATACCTGGGAGCGCGAAGCAGAAAATGAGCGCAGGCA
TTGGTGGGAAATCCATCGGCGTCAGTTTGCCCTGAAAGATATTGTCCTGATTGGCCCGGCAGGCGCTGAACTTTCTGACT
GGCTGCGTGTGATTAAGCGAGAGCATCAGGCTCCATTAGTCAGGCAGGAATCCCTGGGGAAATCGTTGCGTATTGCCAGA
AGCTTCTCTTCTGCTCTTATTGAACGTGAAAAACAACTGGCTCAAATGCTGGTATTGCAATGGAAAAGGCAGCGAGGTAA
GGAATTATTCGTTTCTCCGGAGAAATATTTCTGGCAGGGGAGTCCTGAAGCCTGGCAAGCCTTTGTGGCACAGCTCATTG
AGAGTTTTCCGGGAATTACAGCTCCTGAATTACCTGAGTTATGGCAAGGGGAGAAAACATTATCCGTACTGGCTAATGTT
CTTGCGGACAAGAAACAGCTGGCTAATTTTTTGATTGCCGGGTGCCAGTCTTTATCTCCTGCTTCTGACTCTACTCGTCC
TGCTGGTGAATGCGCAGTACTGTGGCTGGCTGGAAACCAGGGGGACGTCACATTATCCCGTGGTGAATTTTTTGAGCCTT
CTGATAGTGAGTCCCTGCGGCACGTCGCCTTGCGAGCCGAAAAACAGAGCGAACTTAATGAGTCACCCGAACGGTGCATT
CTCTTCTCACACCCGGAACAACCTGAACTCGCCGATTGTGGCTGGAATGTGACCCACAATATCCAGGATGACTACTGGGG
CGATCCTGGAAAGCTTGATGCGCTGGTTGTGATATCGCTCGCTGCAATTACCGCTAAGACTGAAGCAAAACCCTGCGGCT
GGATAGCGTCAGACCCCCTTCATACTTTAGCTCTTGGGATCGTAAAACCAAATGGAAACTGA